| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Megestrol perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Megestrol_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.21926 |
| COL6A3 | collagen, type VI, alpha 3 | 0.214914 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.155561 |
| FN1 | fibronectin 1 | 0.134467 |
| HMGA2 | high mobility group AT-hook 2 | 0.0848925 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0827833 |
| NRXN3 | neurexin 3 | 0.0807753 |
| GLIS3 | GLIS family zinc finger 3 | 0.071395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0661418 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0630617 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0625804 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0549064 |
| NAV1 | neuron navigator 1 | 0.0539575 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0534023 |
| MAP1B | microtubule-associated protein 1B | 0.0528125 |
| LOXL2 | lysyl oxidase-like 2 | 0.052673 |
| EGFR | epidermal growth factor receptor | 0.0508695 |
| CDH13 | cadherin 13 | 0.0505927 |
| EFNA5 | ephrin-A5 | 0.0504896 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0503032 |
| MKI67 | marker of proliferation Ki-67 | 0.0472261 |
| HIP1 | huntingtin interacting protein 1 | 0.0465939 |
| LAMB1 | laminin, beta 1 | 0.0454528 |
| VCL | vinculin | 0.0452362 |
| VEGFC | vascular endothelial growth factor C | 0.0439186 |
| COL5A1 | collagen, type V, alpha 1 | 0.0436604 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0430258 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0421996 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0418216 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0418159 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0403302 |
| VEGFA | vascular endothelial growth factor A | 0.0397337 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0383755 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0375395 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0369596 |
| PRSS23 | protease, serine, 23 | 0.0368687 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0364955 |
| CD44 | CD44 molecule (Indian blood group) | 0.0360785 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0355744 |
| RAI14 | retinoic acid induced 14 | 0.0348478 |
| DST | dystonin | 0.0341437 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0334651 |
| RAD51B | RAD51 paralog B | 0.0329277 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0320529 |
| RUNX1 | runt-related transcription factor 1 | 0.0318993 |
| CALD1 | caldesmon 1 | 0.0318826 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0308198 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0306019 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0303694 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0300839 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0297274 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0294618 |
| RAB31 | RAB31, member RAS oncogene family | 0.0290318 |
| HDAC9 | histone deacetylase 9 | 0.0289319 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0285314 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0283298 |
| TNS3 | tensin 3 | 0.0281696 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0280368 |
| JPH2 | junctophilin 2 | 0.0275569 |
| GOLGB1 | golgin B1 | 0.0274055 |
| PRELID2 | PRELI domain containing 2 | 0.027144 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0270111 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0268064 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0267658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0266337 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0265958 |
| POTEF | POTE ankyrin domain family, member F | 0.0263432 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0258056 |
| RRM2 | ribonucleotide reductase M2 | 0.0254934 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0253027 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0251772 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0250453 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0247248 |
| MYOF | myoferlin | 0.0247123 |
| FNIP1 | folliculin interacting protein 1 | 0.0247007 |
| FMNL2 | formin-like 2 | 0.0246952 |
| LOX | lysyl oxidase | 0.0246435 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0238841 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0238527 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0236656 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0235579 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0229155 |
| ANLN | anillin, actin binding protein | 0.0228314 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0227347 |
| SYNPO | synaptopodin | 0.0226246 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0226158 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0223634 |
| RIN2 | Ras and Rab interactor 2 | 0.022078 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0220433 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.022042 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0219587 |
| NRP1 | neuropilin 1 | 0.0217729 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0216825 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0216332 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0211648 |
| FHIT | fragile histidine triad | 0.0211551 |
| OXR1 | oxidation resistance 1 | 0.021098 |
| FRMD4A | FERM domain containing 4A | 0.0210223 |
| TPM1 | tropomyosin 1 (alpha) | 0.0209789 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0209733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.121413 |
| UBC | ubiquitin C | -0.0961776 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0878994 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0800217 |
| SDC4 | syndecan 4 | -0.0791647 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0696375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0672821 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0637006 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0625018 |
| COL1A2 | collagen, type I, alpha 2 | -0.0591968 |
| CCNI | cyclin I | -0.0586434 |
| TXNIP | thioredoxin interacting protein | -0.0566841 |
| SPAG9 | sperm associated antigen 9 | -0.0565267 |
| PTMA | prothymosin, alpha | -0.0555284 |
| ANXA5 | annexin A5 | -0.0476046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0460152 |
| WTAP | Wilms tumor 1 associated protein | -0.0456272 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0431887 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0431464 |
| ZNF207 | zinc finger protein 207 | -0.0429093 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0419254 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0417668 |
| MT2A | metallothionein 2A | -0.0412728 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0376227 |
| ENO1 | enolase 1, (alpha) | -0.0370866 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.036959 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0366613 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361829 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.035457 |
| FLNB | filamin B, beta | -0.0345197 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0337739 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0335543 |
| JUN | jun proto-oncogene | -0.0328139 |
| IL6 | interleukin 6 | -0.0324315 |
| B2M | beta-2-microglobulin | -0.0320544 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0318813 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0318562 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0309393 |
| RTN4 | reticulon 4 | -0.0304359 |
| SEC24D | SEC24 family member D | -0.0301311 |
| H3-3B | H3.3 histone B | -0.0296176 |
| GANAB | glucosidase, alpha; neutral AB | -0.0294101 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0292336 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0290904 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0286417 |
| PCBP2 | poly(rC) binding protein 2 | -0.0277801 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276109 |
| SRPK2 | SRSF protein kinase 2 | -0.0273907 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0272526 |
| RPS11 | ribosomal protein S11 | -0.0270912 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0270679 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0270236 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0269264 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263865 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.026341 |
| DSCAM | Down syndrome cell adhesion molecule | -0.026299 |
| FAM3C | family with sequence similarity 3, member C | -0.0262657 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0262018 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0252995 |
| RPL32 | ribosomal protein L32 | -0.025294 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0252303 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0251238 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250782 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0250287 |
| CDK7 | cyclin-dependent kinase 7 | -0.0250208 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0248223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0247085 |
| ZNF292 | zinc finger protein 292 | -0.0246707 |
| RPL23 | ribosomal protein L23 | -0.0246376 |
| HDLBP | high density lipoprotein binding protein | -0.0245548 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0242446 |
| ABI1 | abl-interactor 1 | -0.0239912 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0238562 |
| RPS27A | ribosomal protein S27a | -0.0238519 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.023808 |
| FTL | ferritin, light polypeptide | -0.0237821 |
| NOP58 | NOP58 ribonucleoprotein | -0.0237042 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0236653 |
| RLIM | ring finger protein, LIM domain interacting | -0.0236025 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0235112 |
| SEM1 | SEM1 26S proteasome subunit | -0.0234475 |
| ITM2B | integral membrane protein 2B | -0.0234266 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0233656 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0231304 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0231016 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0229869 |
| SEC61G | Sec61 gamma subunit | -0.0229205 |
| AHNAK | AHNAK nucleoprotein | -0.0227446 |
| ZNF326 | zinc finger protein 326 | -0.0226579 |
| ACVR1 | activin A receptor, type I | -0.0226292 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0225551 |
| RPS25 | ribosomal protein S25 | -0.0223109 |
| TFG | TRK-fused gene | -0.0222693 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0220656 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0220528 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0220265 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0217824 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0217357 |
| NUCB2 | nucleobindin 2 | -0.0217286 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0217266 |
