Melioidosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain. (Human Disease Ontology, DOID_5052)
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Genes

172 genes co-occuring with the disease Melioidosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
IFNG interferon, gamma 2.483
TLR5 toll-like receptor 5 2.247
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.204
SAMM50 SAMM50 sorting and assembly machinery component 2.132
IL18 interleukin 18 2.109
IL1B interleukin 1, beta 2.099
NLRC4 NLR family, CARD domain containing 4 2.093
TLR4 toll-like receptor 4 2.088
TLR2 toll-like receptor 2 2.074
TNF tumor necrosis factor 2.037
IL10 interleukin 10 2.019
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.01
IL6 interleukin 6 2.008
NCAPD3 non-SMC condensin II complex, subunit D3 1.973
MXI1 MAX interactor 1, dimerization protein 1.953
TFCP2 transcription factor CP2 1.942
CD4 CD4 molecule 1.93
CALHM6 calcium homeostasis modulator family member 6 1.889
CRP C-reactive protein, pentraxin-related 1.837
CD8A CD8a molecule 1.825
LY96 lymphocyte antigen 96 1.801
RAD51 RAD51 recombinase 1.793
ASPHD2 aspartate beta-hydroxylase domain containing 2 1.781
MYD88 myeloid differentiation primary response 88 1.776
CSF3 colony stimulating factor 3 (granulocyte) 1.704
TLR1 toll-like receptor 1 1.699
CAMP cathelicidin antimicrobial peptide 1.644
PAQR7 progestin and adipoQ receptor family member VII 1.639
GSDMD gasdermin D 1.623
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.622
LTF lactotransferrin 1.612
IL17A interleukin 17A 1.606
ALB albumin 1.6
IL1A interleukin 1, alpha 1.594
CXCL8 chemokine (C-X-C motif) ligand 8 1.587
VWA1 von Willebrand factor A domain containing 1 1.546
IFNB1 interferon, beta 1, fibroblast 1.543
VIPR1 vasoactive intestinal peptide receptor 1 1.532
SARM1 sterile alpha and TIR motif containing 1 1.519
TLR6 toll-like receptor 6 1.514
NAIP NLR family, apoptosis inhibitory protein 1.505
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.503
FOXL2 forkhead box L2 1.489
IL4 interleukin 4 1.486
SEC11C SEC11 homolog C (S. cerevisiae) 1.47
ARID4B AT rich interactive domain 4B (RBP1-like) 1.463
TLR10 toll-like receptor 10 1.451
TREM1 triggering receptor expressed on myeloid cells 1 1.45
CTSA cathepsin A 1.438
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.428
LAMP1 lysosomal-associated membrane protein 1 1.426
SEC11A SEC11 homolog A (S. cerevisiae) 1.422
AIM2 absent in melanoma 2 1.414
ERVW-1 endogenous retrovirus group W, member 1 1.413
PCDH8 protocadherin 8 1.404
CCL2 chemokine (C-C motif) ligand 2 1.401
CXCL9 chemokine (C-X-C motif) ligand 9 1.39
IL15 interleukin 15 1.385
SPI1 Spi-1 proto-oncogene 1.381
RAB32 RAB32, member RAS oncogene family 1.378
ERV3-1 endogenous retrovirus group 3, member 1 1.371
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.371
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.368
IL2 interleukin 2 1.365
NOD2 nucleotide-binding oligomerization domain containing 2 1.364
IRAK3 interleukin-1 receptor-associated kinase 3 1.363
ELANE elastase, neutrophil expressed 1.351
INS insulin 1.351
R3HCC1L R3H domain and coiled-coil containing 1-like 1.346
IL1R1 interleukin 1 receptor, type I 1.343
SLC22A18 solute carrier family 22, member 18 1.341
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.312
C3 complement component 3 1.31
NOD1 nucleotide-binding oligomerization domain containing 1 1.293
TLR9 toll-like receptor 9 1.29
PPP4R3C protein phosphatase 4 regulatory subunit 3C 1.289
GNG8 guanine nucleotide binding protein (G protein), gamma 8 1.278
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.278
IL18R1 interleukin 18 receptor 1 1.275
SOCS3 suppressor of cytokine signaling 3 1.269
CXCL10 chemokine (C-X-C motif) ligand 10 1.263
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.253
CCL3 chemokine (C-C motif) ligand 3 1.244
MPO myeloperoxidase 1.244
STAT1 signal transducer and activator of transcription 1, 91kDa 1.242
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.24
GALP galanin-like peptide 1.24
TSSK4 testis-specific serine kinase 4 1.239
TLR3 toll-like receptor 3 1.231
IL27 interleukin 27 1.229
TBL1X transducin (beta)-like 1X-linked 1.224
PXDNL peroxidasin-like 1.217
PXDN peroxidasin 1.216
CCL5 chemokine (C-C motif) ligand 5 1.212
ATP5PF ATP synthase peripheral stalk subunit F6 1.199
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1.196
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.194
TLR7 toll-like receptor 7 1.193
IL27RA interleukin 27 receptor, alpha 1.192
CENPC centromere protein C 1.187
NLRP3 NLR family, pyrin domain containing 3 1.183
EIF4A1 eukaryotic translation initiation factor 4A1 1.179
UGDH UDP-glucose 6-dehydrogenase 1.174
EIF4A2 eukaryotic translation initiation factor 4A2 1.173
DEFB103A defensin, beta 103A 1.168
IL12RB1 interleukin 12 receptor, beta 1 1.167
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.166
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.162
VASP vasodilator-stimulated phosphoprotein 1.162
TSPO translocator protein (18kDa) 1.146
ESX1 ESX homeobox 1 1.141
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.138
PTAFR platelet-activating factor receptor 1.136
IRAK1 interleukin-1 receptor-associated kinase 1 1.136
IFNA1 interferon, alpha 1 1.134
ATG10 autophagy related 10 1.129
TRAF3 TNF receptor-associated factor 3 1.113
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.11
HSPE1 heat shock 10kDa protein 1 1.11
CYBB cytochrome b-245, beta polypeptide 1.104
NCF1 neutrophil cytosolic factor 1 1.104
PET100 PET100 homolog (S. cerevisiae) 1.104
CA5B carbonic anhydrase VB, mitochondrial 1.103
TLR8 toll-like receptor 8 1.101
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.099
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 1.097
CA8 carbonic anhydrase VIII 1.096
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 1.096
GBP5 guanylate binding protein 5 1.096
IL1R2 interleukin 1 receptor, type II 1.095
GBP1 guanylate binding protein 1, interferon-inducible 1.089
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.089
IL5 interleukin 5 1.087
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.084
CD160 CD160 molecule 1.084
PLG plasminogen 1.083
CGAS cyclic GMP-AMP synthase 1.082
CA13 carbonic anhydrase XIII 1.082
U2SURP U2 snRNP-associated SURP domain containing 1.076
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.07
RABIF RAB interacting factor 1.062
CA14 carbonic anhydrase XIV 1.06
HLA-DOB major histocompatibility complex, class II, DO beta 1.052
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.051
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.05
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.049
NBR1 neighbor of BRCA1 gene 1 1.048
MTG2 mitochondrial ribosome-associated GTPase 2 1.044
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.044
METAP1 methionyl aminopeptidase 1 1.039
NASP nuclear autoantigenic sperm protein (histone-binding) 1.039
STAP2 signal transducing adaptor family member 2 1.038
IFNGR1 interferon gamma receptor 1 1.037
WDR11 WD repeat domain 11 1.028
IL13 interleukin 13 1.025
LARS1 leucyl-tRNA synthetase 1 1.023
DEFB4A defensin, beta 4A 1.022
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.022
HTN3 histatin 3 1.022
ACTA1 actin, alpha 1, skeletal muscle 1.022
CA5A carbonic anhydrase VA, mitochondrial 1.02
HLA-C major histocompatibility complex, class I, C 1.019
HABP2 hyaluronan binding protein 2 1.019
RAB34 RAB34, member RAS oncogene family 1.018
ADCY10 adenylate cyclase 10 (soluble) 1.015
NLRP1 NLR family, pyrin domain containing 1 1.012
WARS1 tryptophanyl-tRNA synthetase 1 1.011
JUN jun proto-oncogene 1.009
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.004
CA6 carbonic anhydrase VI 1.003
HLA-DOA major histocompatibility complex, class II, DO alpha 1.002
CBS cystathionine-beta-synthase 1.001