| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/54677470 |
| Similar Terms | |
| Downloads & Tools |
198 proteins with high or low expression in Meloxicam relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZG16B | zymogen granule protein 16B | 4.54 |
| PIP | prolactin-induced protein | 2.08 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.9 |
| RNF4 | ring finger protein 4 | 0.8 |
| WDR20 | WD repeat domain 20 | 0.66 |
| BCOR | BCL6 corepressor | 0.55 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.54 |
| BRK1 | BRICK1, SCAR/WAVE actin-nucleating complex subunit | 0.47 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.44 |
| FAM171A2 | family with sequence similarity 171, member A2 | 0.44 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | 0.43 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.43 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.43 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.4 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.39 |
| SET | SET nuclear proto-oncogene | 0.35 |
| KLHL29 | kelch-like family member 29 | 0.35 |
| DDN | dendrin | 0.34 |
| DUSP7 | dual specificity phosphatase 7 | 0.34 |
| TEP1 | telomerase-associated protein 1 | 0.34 |
| SLC25A44 | solute carrier family 25, member 44 | 0.32 |
| FAM161A | family with sequence similarity 161, member A | 0.32 |
| CCDC77 | coiled-coil domain containing 77 | 0.32 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.32 |
| AXIN2 | axin 2 | 0.31 |
| CCDC57 | coiled-coil domain containing 57 | 0.3 |
| ETV6 | ets variant 6 | 0.3 |
| ZNF92 | zinc finger protein 92 | 0.3 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.29 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | 0.29 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.28 |
| CADPS | Ca++-dependent secretion activator | 0.28 |
| ZNF566 | zinc finger protein 566 | 0.28 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.27 |
| RNF220 | ring finger protein 220 | 0.27 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.27 |
| FAR1 | fatty acyl CoA reductase 1 | 0.27 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.27 |
| GTF3C6 | general transcription factor IIIC, polypeptide 6, alpha 35kDa | 0.27 |
| ZNF692 | zinc finger protein 692 | 0.26 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.26 |
| KIAA1210 | KIAA1210 | 0.26 |
| PUM1 | pumilio RNA-binding family member 1 | 0.25 |
| SLC25A39 | solute carrier family 25, member 39 | 0.25 |
| ZGRF1 | zinc finger, GRF-type containing 1 | 0.25 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.25 |
| ACE | angiotensin I converting enzyme | 0.25 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.24 |
| IL17RB | interleukin 17 receptor B | 0.24 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.24 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.24 |
| CALU | calumenin | 0.23 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.23 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.23 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.23 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.22 |
| GUCD1 | guanylyl cyclase domain containing 1 | 0.22 |
| RNF166 | ring finger protein 166 | 0.22 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.22 |
| CCDC170 | coiled-coil domain containing 170 | 0.22 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.22 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.22 |
| CD320 | CD320 molecule | 0.22 |
| OBSL1 | obscurin-like 1 | 0.22 |
| POLQ | polymerase (DNA directed), theta | 0.22 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.22 |
| PRDM4 | PR domain containing 4 | 0.22 |
| ZNF584 | zinc finger protein 584 | 0.21 |
| PKNOX1 | PBX/knotted 1 homeobox 1 | 0.21 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.21 |
| GYG1 | glycogenin 1 | 0.21 |
| PEX12 | peroxisomal biogenesis factor 12 | 0.21 |
| L1RE1 | LINE1 retrotransposable element 1 | 0.21 |
| ZNF597 | zinc finger protein 597 | 0.21 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.21 |
| MRAS | muscle RAS oncogene homolog | 0.21 |
| ZNF536 | zinc finger protein 536 | 0.21 |
| PRR36 | proline rich 36 | 0.21 |
| CENPH | centromere protein H | 0.21 |
| MDM4 | MDM4, p53 regulator | 0.21 |
| CSNK1D | casein kinase 1, delta | 0.21 |
| ZNF428 | zinc finger protein 428 | 0.2 |
| TBC1D31 | TBC1 domain family, member 31 | 0.2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 0.2 |
| CDC34 | cell division cycle 34 | 0.2 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.2 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.2 |
| NAF1 | nuclear assembly factor 1 ribonucleoprotein | 0.2 |
| TMEM104 | transmembrane protein 104 | 0.2 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.2 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.2 |
| ZSCAN21 | zinc finger and SCAN domain containing 21 | 0.2 |
| TPM2 | tropomyosin 2 (beta) | 0.2 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.2 |
| CCNI | cyclin I | 0.2 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | 0.2 |
| C1ORF43 | chromosome 1 open reading frame 43 | 0.2 |
| ZNF668 | zinc finger protein 668 | 0.2 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.19 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -1.03 |
| ITGA1 | integrin, alpha 1 | -0.74 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.63 |
| SLC41A3 | solute carrier family 41, member 3 | -0.6 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.54 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.5 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.49 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.46 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.46 |
| TCEA2 | transcription elongation factor A (SII), 2 | -0.45 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.43 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.43 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.41 |
| ZFP36 | ZFP36 ring finger protein | -0.4 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | -0.39 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | -0.38 |
| SARDH | sarcosine dehydrogenase | -0.38 |
| MT1X | metallothionein 1X | -0.38 |
| MT1L | metallothionein 1L (gene/pseudogene) | -0.38 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -0.36 |
| RPE | ribulose-5-phosphate-3-epimerase | -0.36 |
| ANGPTL4 | angiopoietin-like 4 | -0.36 |
| ADIRF | adipogenesis regulatory factor | -0.34 |
| GID8 | GID complex subunit 8 | -0.34 |
| DCLRE1C | DNA cross-link repair 1C | -0.34 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.34 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | -0.34 |
| MIIP | migration and invasion inhibitory protein | -0.34 |
| RNF13 | ring finger protein 13 | -0.33 |
| ZNF165 | zinc finger protein 165 | -0.33 |
| ADCY10 | adenylate cyclase 10 (soluble) | -0.33 |
| AKNA | AT-hook transcription factor | -0.33 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.31 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.31 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.31 |
| PEX19 | peroxisomal biogenesis factor 19 | -0.31 |
| GGACT | gamma-glutamylamine cyclotransferase | -0.3 |
| FN1 | fibronectin 1 | -0.3 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.3 |
| CLDN3 | claudin 3 | -0.3 |
| SF1 | splicing factor 1 | -0.3 |
| MEGF8 | multiple EGF-like-domains 8 | -0.3 |
| ARHGAP28 | Rho GTPase activating protein 28 | -0.29 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.29 |
| ZDHHC21 | zinc finger, DHHC-type containing 21 | -0.29 |
| PXDN | peroxidasin | -0.29 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.29 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.28 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.28 |
| MATR3 | matrin 3 | -0.27 |
| NENF | neudesin neurotrophic factor | -0.27 |
| CCDC158 | coiled-coil domain containing 158 | -0.27 |
| NMNAT3 | nicotinamide nucleotide adenylyltransferase 3 | -0.27 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.26 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | -0.26 |
| SERF2 | small EDRK-rich factor 2 | -0.26 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | -0.26 |
| ARG2 | arginase 2 | -0.26 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | -0.26 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -0.25 |
| CTHRC1 | collagen triple helix repeat containing 1 | -0.25 |
| PRMT6 | protein arginine methyltransferase 6 | -0.25 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.25 |
| SLC38A7 | solute carrier family 38, member 7 | -0.25 |
| MFAP3 | microfibrillar-associated protein 3 | -0.25 |
| SERINC5 | serine incorporator 5 | -0.25 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -0.24 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | -0.24 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.24 |
| RHOD | ras homolog family member D | -0.24 |
| ACVR1B | activin A receptor, type IB | -0.24 |
| MPZL2 | myelin protein zero-like 2 | -0.24 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.24 |
| HTD2 | hydroxyacyl-thioester dehydratase type 2 | -0.24 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.24 |
| BAK1 | BCL2-antagonist/killer 1 | -0.24 |
| TMEM199 | transmembrane protein 199 | -0.24 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.23 |
| ARMC7 | armadillo repeat containing 7 | -0.23 |
| RPAIN | RPA interacting protein | -0.23 |
| FANCL | Fanconi anemia, complementation group L | -0.23 |
| PNPLA2 | patatin-like phospholipase domain containing 2 | -0.23 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -0.23 |
| POLH | polymerase (DNA directed), eta | -0.23 |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | -0.23 |
| FUT10 | fucosyltransferase 10 (alpha (1,3) fucosyltransferase) | -0.23 |
| TTN | titin | -0.23 |
| CDK18 | cyclin-dependent kinase 18 | -0.23 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -0.23 |
| CHRD | chordin | -0.23 |
| FAM89A | family with sequence similarity 89, member A | -0.22 |
| CAB39L | calcium binding protein 39-like | -0.22 |
| ITM2C | integral membrane protein 2C | -0.22 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -0.22 |
| ABHD3 | abhydrolase domain containing 3 | -0.22 |
| LETMD1 | LETM1 domain containing 1 | -0.22 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.22 |
| CPA4 | carboxypeptidase A4 | -0.22 |
