| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Meloxicam_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.122657 |
| COL1A2 | collagen, type I, alpha 2 | 0.117354 |
| COL3A1 | collagen, type III, alpha 1 | 0.105621 |
| FBN1 | fibrillin 1 | 0.0983833 |
| SEPTIN9 | septin 9 | 0.0915906 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0608965 |
| TXNIP | thioredoxin interacting protein | 0.0504181 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0501965 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0499695 |
| B2M | beta-2-microglobulin | 0.0484313 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0482168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0465646 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446432 |
| ARRDC3 | arrestin domain containing 3 | 0.0436185 |
| MYADM | myeloid-associated differentiation marker | 0.0433986 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0426726 |
| STC1 | stanniocalcin 1 | 0.0426143 |
| PLAT | plasminogen activator, tissue | 0.0412012 |
| MT1X | metallothionein 1X | 0.0410949 |
| SFTPA2 | surfactant protein A2 | 0.0405108 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0397714 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0367829 |
| APP | amyloid beta (A4) precursor protein | 0.0367498 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0358892 |
| GLIS3 | GLIS family zinc finger 3 | 0.0355819 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0355237 |
| CLU | clusterin | 0.0352424 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0343174 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0328245 |
| TMSB4X | thymosin beta 4, X-linked | 0.0328099 |
| GSE1 | Gse1 coiled-coil protein | 0.0324315 |
| LOX | lysyl oxidase | 0.0319601 |
| LAMB1 | laminin, beta 1 | 0.0317027 |
| RAB10 | RAB10, member RAS oncogene family | 0.0314663 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0313858 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0309673 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0308496 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0308434 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0305307 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0300081 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0298466 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0296682 |
| THBS2 | thrombospondin 2 | 0.0292614 |
| TPM3 | tropomyosin 3 | 0.0288242 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.028788 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0281594 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0279628 |
| SDC4 | syndecan 4 | 0.0277581 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.02669 |
| FAT1 | FAT atypical cadherin 1 | 0.0263655 |
| TAGLN2 | transgelin 2 | 0.0263589 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0263089 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0260232 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0251822 |
| HLA-A | major histocompatibility complex, class I, A | 0.0249798 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0247796 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0244951 |
| HMGB2 | high mobility group box 2 | 0.0243991 |
| CTSB | cathepsin B | 0.0241609 |
| PFKP | phosphofructokinase, platelet | 0.0240493 |
| PLEC | plectin | 0.0238177 |
| COL5A2 | collagen, type V, alpha 2 | 0.0237853 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237815 |
| CD99 | CD99 molecule | 0.023696 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0236397 |
| NEFL | neurofilament, light polypeptide | 0.0235976 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0235879 |
| UBC | ubiquitin C | 0.0235662 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0234477 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0233076 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0232858 |
| RBM25 | RNA binding motif protein 25 | 0.0231731 |
| HDLBP | high density lipoprotein binding protein | 0.0230786 |
| SMAD3 | SMAD family member 3 | 0.0230564 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224857 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.022329 |
| CD44 | CD44 molecule (Indian blood group) | 0.0219126 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0217209 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0209466 |
| TRIM22 | tripartite motif containing 22 | 0.0208028 |
| SVIL | supervillin | 0.0207963 |
| ATP13A3 | ATPase type 13A3 | 0.0207902 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0207158 |
| AFAP1 | actin filament associated protein 1 | 0.020491 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0203192 |
| HLA-E | major histocompatibility complex, class I, E | 0.020302 |
| CENPF | centromere protein F, 350/400kDa | 0.020165 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0201188 |
| GPC6 | glypican 6 | 0.0201169 |
| DENND2B | DENN domain containing 2B | 0.0199647 |
| SET | SET nuclear proto-oncogene | 0.0198172 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0197784 |
| BPTF | bromodomain PHD finger transcription factor | 0.0197229 |
| IPO7 | importin 7 | 0.0196355 |
| S100A4 | S100 calcium binding protein A4 | 0.0195548 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0195126 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0192598 |
| MAP1B | microtubule-associated protein 1B | 0.0192345 |
| BSG | basigin (Ok blood group) | 0.0189756 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0187664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.18807 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.145686 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.117795 |
| CDH13 | cadherin 13 | -0.107593 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.103051 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0958817 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0948063 |
| S100A10 | S100 calcium binding protein A10 | -0.0808496 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0717334 |
| CSTB | cystatin B (stefin B) | -0.0709785 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0646947 |
| PODXL | podocalyxin-like | -0.0626274 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0620178 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0579609 |
| VIM | vimentin | -0.057861 |
| NDRG1 | N-myc downstream regulated 1 | -0.05742 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0546591 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0532737 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0531869 |
| SQSTM1 | sequestosome 1 | -0.0529778 |
| DST | dystonin | -0.0522677 |
| NAV1 | neuron navigator 1 | -0.0516163 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0515372 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0487617 |
| DCLK2 | doublecortin-like kinase 2 | -0.048458 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0444326 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0441289 |
| MSI2 | musashi RNA-binding protein 2 | -0.0439002 |
| AUTS2 | autism susceptibility candidate 2 | -0.0420814 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.041633 |
| EGFR | epidermal growth factor receptor | -0.0415873 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0407405 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0402807 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0392278 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0385241 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0371638 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0368941 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0363618 |
| RPL35A | ribosomal protein L35a | -0.0358415 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0352352 |
| PTMA | prothymosin, alpha | -0.0344171 |
| ANXA2 | annexin A2 | -0.0343779 |
| SPAG9 | sperm associated antigen 9 | -0.0342047 |
| VCL | vinculin | -0.0333953 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0332228 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0330298 |
| FBXO11 | F-box protein 11 | -0.0326465 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0323492 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0318514 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0318299 |
| FTL | ferritin, light polypeptide | -0.031696 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316258 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308461 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0304165 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0302287 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0300557 |
| SP100 | SP100 nuclear antigen | -0.0298466 |
| RPL37A | ribosomal protein L37a | -0.0291313 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0291193 |
| FN1 | fibronectin 1 | -0.0287958 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0286806 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282987 |
| CUX1 | cut-like homeobox 1 | -0.0279022 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0275579 |
| CANX | calnexin | -0.02744 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0271607 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0271404 |
| ADM | adrenomedullin | -0.0269899 |
| CYTH3 | cytohesin 3 | -0.0265258 |
| GOLGA4 | golgin A4 | -0.0261967 |
| GOLGB1 | golgin B1 | -0.026002 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0257458 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0256857 |
| FAM107B | family with sequence similarity 107, member B | -0.025522 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.02536 |
| SEC61G | Sec61 gamma subunit | -0.0253567 |
| COL5A1 | collagen, type V, alpha 1 | -0.0253121 |
| RASAL2 | RAS protein activator like 2 | -0.0250538 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0249692 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0246526 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0245481 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0245476 |
| CD109 | CD109 molecule | -0.0244774 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0244613 |
| ATXN1 | ataxin 1 | -0.0243664 |
| HELZ | helicase with zinc finger | -0.0241995 |
| RPL36 | ribosomal protein L36 | -0.0240641 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0240498 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0236302 |
| PGK1 | phosphoglycerate kinase 1 | -0.0235427 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0234347 |
| FNIP1 | folliculin interacting protein 1 | -0.0234066 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0233359 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0230688 |
| NAV2 | neuron navigator 2 | -0.0229617 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0229121 |
| RPL28 | ribosomal protein L28 | -0.0227074 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0225572 |
| RUNX1 | runt-related transcription factor 1 | -0.0223535 |
| COPA | coatomer protein complex, subunit alpha | -0.0222422 |
