| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Meloxicam_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.154828 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0949042 |
| AREG | amphiregulin | 0.0773493 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0766627 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0701277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0637423 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0551411 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0519507 |
| TMEM41B | transmembrane protein 41B | 0.0459216 |
| TXNRD1 | thioredoxin reductase 1 | 0.0413564 |
| CPOX | coproporphyrinogen oxidase | 0.0376411 |
| ATP11A | ATPase, class VI, type 11A | 0.0365274 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.034223 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0327388 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0311827 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308864 |
| HLTF | helicase-like transcription factor | 0.0300256 |
| CCNL1 | cyclin L1 | 0.0291754 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0290862 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0288411 |
| EDN1 | endothelin 1 | 0.0280934 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0280887 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0279138 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0278873 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0272772 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.02679 |
| VMP1 | vacuole membrane protein 1 | 0.0264967 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264815 |
| ARRDC3 | arrestin domain containing 3 | 0.02632 |
| PCBP2 | poly(rC) binding protein 2 | 0.0255194 |
| PLEC | plectin | 0.024863 |
| TPM3 | tropomyosin 3 | 0.02446 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0241987 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0238439 |
| RPL3 | ribosomal protein L3 | 0.0235801 |
| KIF5B | kinesin family member 5B | 0.0234834 |
| CCDC200 | coiled-coil domain containing 200 | 0.0232916 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0229614 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0227339 |
| CDK17 | cyclin-dependent kinase 17 | 0.02219 |
| ANXA1 | annexin A1 | 0.021009 |
| EZR | ezrin | 0.0201498 |
| RRM2 | ribonucleotide reductase M2 | 0.0197036 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0195982 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0193097 |
| CLDND1 | claudin domain containing 1 | 0.0188658 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0186559 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.0185879 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0184508 |
| EXOC6B | exocyst complex component 6B | 0.0184078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0183189 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0182217 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0178589 |
| LMO7 | LIM domain 7 | 0.0175984 |
| TFG | TRK-fused gene | 0.0173295 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0173075 |
| WWOX | WW domain containing oxidoreductase | 0.017073 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0167683 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0165622 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0165099 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0163334 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0163304 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0163195 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0160805 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0160486 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0159692 |
| CEP192 | centrosomal protein 192kDa | 0.0159306 |
| CALR | calreticulin | 0.0158939 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0157395 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0156454 |
| MSH6 | mutS homolog 6 | 0.0156388 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0155396 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0153195 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0152533 |
| SFTPA2 | surfactant protein A2 | 0.0152145 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0150584 |
| SERINC1 | serine incorporator 1 | 0.0150572 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0148335 |
| OGA | O-GlcNAcase | 0.0146899 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0146825 |
| TJP1 | tight junction protein 1 | 0.0145907 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.014569 |
| NBEA | neurobeachin | 0.0143635 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0143493 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0139321 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0137879 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0137017 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0136802 |
| ITGA6 | integrin, alpha 6 | 0.0135382 |
| HLA-A | major histocompatibility complex, class I, A | 0.0134857 |
| CCND1 | cyclin D1 | 0.0133701 |
| CLPTM1L | CLPTM1-like | 0.0133226 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0131927 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0131842 |
| CD164 | CD164 molecule, sialomucin | 0.0131776 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.0131545 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0130552 |
| SSRP1 | structure specific recognition protein 1 | 0.0128942 |
| STYK1 | serine/threonine/tyrosine kinase 1 | 0.0128725 |
| TRIM41 | tripartite motif containing 41 | 0.0128103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.234061 |
| TMSB10 | thymosin beta 10 | -0.166382 |
| ACTG1 | actin gamma 1 | -0.0813093 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0688563 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0678898 |
| RPS8 | ribosomal protein S8 | -0.0592776 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0570049 |
| FTL | ferritin, light polypeptide | -0.0538124 |
| PTMA | prothymosin, alpha | -0.05122 |
| TPI1 | triosephosphate isomerase 1 | -0.0502964 |
| VIM | vimentin | -0.0499931 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0486752 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0470573 |
| RASAL2 | RAS protein activator like 2 | -0.0456791 |
| RPL19 | ribosomal protein L19 | -0.0453765 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0441147 |
| RPS6 | ribosomal protein S6 | -0.0426034 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0420553 |
| HMGA1 | high mobility group AT-hook 1 | -0.0416581 |
| RPL12 | ribosomal protein L12 | -0.0414962 |
| HMGA2 | high mobility group AT-hook 2 | -0.0413414 |
| RPL35A | ribosomal protein L35a | -0.041239 |
| EHBP1 | EH domain binding protein 1 | -0.0397414 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0390904 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0385677 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0378219 |
| BCHE | butyrylcholinesterase | -0.0376951 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.035682 |
| RPL37A | ribosomal protein L37a | -0.0355573 |
| RPL23 | ribosomal protein L23 | -0.0351503 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0348752 |
| S100A10 | S100 calcium binding protein A10 | -0.0348243 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0347924 |
| MKI67 | marker of proliferation Ki-67 | -0.0342036 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336918 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0336417 |
| RPL34 | ribosomal protein L34 | -0.0329148 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0326951 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0322762 |
| RPS3 | ribosomal protein S3 | -0.0320284 |
| RPL11 | ribosomal protein L11 | -0.0316038 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0313003 |
| PFN1 | profilin 1 | -0.03093 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0305268 |
| RPS29 | ribosomal protein S29 | -0.0300483 |
| FNIP1 | folliculin interacting protein 1 | -0.0300181 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299836 |
| SYT1 | synaptotagmin I | -0.0297148 |
| RPLP2 | ribosomal protein, large, P2 | -0.0294575 |
| H1-0 | H1.0 linker histone | -0.0294256 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0286271 |
| RPS12 | ribosomal protein S12 | -0.0282764 |
| RPS16 | ribosomal protein S16 | -0.0278621 |
| EGR1 | early growth response 1 | -0.0275714 |
| ANKRD28 | ankyrin repeat domain 28 | -0.027558 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0275219 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0272079 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0270298 |
| RPL36 | ribosomal protein L36 | -0.0266831 |
| RPL38 | ribosomal protein L38 | -0.0264903 |
| TUBA1B | tubulin, alpha 1b | -0.0264032 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.025847 |
| ZNF804A | zinc finger protein 804A | -0.0257855 |
| RPS14 | ribosomal protein S14 | -0.0255532 |
| RPS25 | ribosomal protein S25 | -0.0251407 |
| CLDN1 | claudin 1 | -0.0250364 |
| RPS23 | ribosomal protein S23 | -0.0250066 |
| PCDH7 | protocadherin 7 | -0.0248591 |
| HMGB1 | high mobility group box 1 | -0.0247545 |
| RPL8 | ribosomal protein L8 | -0.0246573 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.024614 |
| RPL26 | ribosomal protein L26 | -0.0245693 |
| YBX3 | Y box binding protein 3 | -0.0244266 |
| SETD5 | SET domain containing 5 | -0.0241655 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0241408 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0240637 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0239525 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0239336 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0236898 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0236226 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0234446 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0233824 |
| RPS27A | ribosomal protein S27a | -0.0230269 |
| RPL28 | ribosomal protein L28 | -0.0230263 |
| S100A6 | S100 calcium binding protein A6 | -0.0229405 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0227957 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0225543 |
| RPL37 | ribosomal protein L37 | -0.0224236 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0222765 |
| DST | dystonin | -0.0222539 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0222465 |
| RPL31 | ribosomal protein L31 | -0.0217543 |
| NAV3 | neuron navigator 3 | -0.0216214 |
| FAM162A | family with sequence similarity 162, member A | -0.0215933 |
| LDHB | lactate dehydrogenase B | -0.0215681 |
| MAP4 | microtubule-associated protein 4 | -0.0215204 |
| RPS17 | ribosomal protein S17 | -0.0214101 |
| RPS13 | ribosomal protein S13 | -0.021342 |
| RPL27 | ribosomal protein L27 | -0.0213372 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0213221 |
