Meloxicam_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Meloxicam perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Meloxicam_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0864963
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0748059
MACC1 metastasis associated in colon cancer 1 0.0674684
ITGA6 integrin, alpha 6 0.061715
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0611829
RNF213 ring finger protein 213 0.0609933
EPHB2 EPH receptor B2 0.0603441
EPSTI1 epithelial stromal interaction 1 (breast) 0.0491319
STK24 serine/threonine kinase 24 0.0441555
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0432196
MX1 MX dynamin-like GTPase 1 0.0386823
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0351891
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0351808
MSI2 musashi RNA-binding protein 2 0.0326581
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0314181
RABGAP1L RAB GTPase activating protein 1-like 0.029252
HDAC4 histone deacetylase 4 0.0292368
ZNRF3 zinc and ring finger 3 0.0286111
NAMPT nicotinamide phosphoribosyltransferase 0.0282936
ARHGAP26 Rho GTPase activating protein 26 0.0280406
ATP11A ATPase, class VI, type 11A 0.027648
SFPQ splicing factor proline/glutamine-rich 0.0274572
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0273754
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0253406
OCLN occludin 0.0248776
DIAPH3 diaphanous-related formin 3 0.0240978
MYH9 myosin, heavy chain 9, non-muscle 0.0238321
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0233632
DMBT1 deleted in malignant brain tumors 1 0.0231669
RIGI RNA sensor RIG-I 0.023099
RUNX1 runt-related transcription factor 1 0.0228214
CDHR2 cadherin-related family member 2 0.0226488
SPATA13 spermatogenesis associated 13 0.0220038
DSCAM Down syndrome cell adhesion molecule 0.0219948
TRIM2 tripartite motif containing 2 0.0219036
SREBF2 sterol regulatory element binding transcription factor 2 0.0217357
EREG epiregulin 0.0209197
ETNK1 ethanolamine kinase 1 0.0203998
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0203513
CENPF centromere protein F, 350/400kDa 0.0202335
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0200608
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0194982
SEPTIN9 septin 9 0.0193768
BRCA2 breast cancer 2, early onset 0.0192812
CTBP2 C-terminal binding protein 2 0.0192731
MX2 MX dynamin-like GTPase 2 0.0190438
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0188904
SAMHD1 SAM domain and HD domain 1 0.0181153
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0180415
LNPEP leucyl/cystinyl aminopeptidase 0.0180378
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.0180084
TRAF5 TNF receptor-associated factor 5 0.0179433
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.017864
CANX calnexin 0.0177485
CFB complement factor B 0.017435
SMC4 structural maintenance of chromosomes 4 0.0173326
GMDS GDP-mannose 4,6-dehydratase 0.0172066
ACTN4 actinin, alpha 4 0.0171576
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.0170575
GSK3B glycogen synthase kinase 3 beta 0.0170282
VMP1 vacuole membrane protein 1 0.0166301
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.0165432
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0163306
ARHGAP11A Rho GTPase activating protein 11A 0.0162001
OSBPL10 oxysterol binding protein-like 10 0.0159736
PDE4D phosphodiesterase 4D, cAMP-specific 0.0159141
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0158324
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0157973
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0157817
CHD6 chromodomain helicase DNA binding protein 6 0.0157671
STARD4 StAR-related lipid transfer (START) domain containing 4 0.0157301
GSDMB gasdermin B 0.0157161
ARL5B ADP-ribosylation factor-like 5B 0.0156432
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0155295
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0153907
HMGB2 high mobility group box 2 0.0153686
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0153655
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.015273
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.0152728
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0151803
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0150556
ITGB8 integrin, beta 8 0.015022
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.0148822
RPL3 ribosomal protein L3 0.0148677
ETV6 ets variant 6 0.0148631
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.0143397
WARS1 tryptophanyl-tRNA synthetase 1 0.0143197
STIL SCL/TAL1 interrupting locus 0.0142961
PRSS22 protease, serine, 22 0.0141909
RFC3 replication factor C (activator 1) 3, 38kDa 0.0141112
LYZ lysozyme 0.0140667
HP1BP3 heterochromatin protein 1, binding protein 3 0.0140606
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0140233
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.0137114
HYOU1 hypoxia up-regulated 1 0.0137025
PHF11 PHD finger protein 11 0.0136499
PLEC plectin 0.0136484
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0135913
AARS1 alanyl-tRNA synthetase 1 0.0135768
YAP1 Yes-associated protein 1 0.0135629

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.216741
TPT1 tumor protein, translationally-controlled 1 -0.185322
B2M beta-2-microglobulin -0.171509
HLA-B major histocompatibility complex, class I, B -0.0981942
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0875496
ZMYND8 zinc finger, MYND-type containing 8 -0.0874736
TXNIP thioredoxin interacting protein -0.0809573
FTL ferritin, light polypeptide -0.0800592
C6ORF132 chromosome 6 open reading frame 132 -0.0767634
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0765751
EGR1 early growth response 1 -0.0762951
PTMA prothymosin, alpha -0.0755645
MT2A metallothionein 2A -0.0748176
TMSB10 thymosin beta 10 -0.0711612
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0693628
NCKAP5 NCK-associated protein 5 -0.068435
GOLGB1 golgin B1 -0.068342
NDRG1 N-myc downstream regulated 1 -0.067767
RPL35A ribosomal protein L35a -0.0656379
ANXA2 annexin A2 -0.0654586
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0652194
FTH1 ferritin, heavy polypeptide 1 -0.0638468
P4HB prolyl 4-hydroxylase, beta polypeptide -0.062991
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.0623597
LCN2 lipocalin 2 -0.0608372
IFI6 interferon, alpha-inducible protein 6 -0.0598056
GCC2 GRIP and coiled-coil domain containing 2 -0.0596588
AHI1 Abelson helper integration site 1 -0.0592672
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0590334
MUC20 mucin 20, cell surface associated -0.0573248
RAB7A RAB7A, member RAS oncogene family -0.0567141
RPLP1 ribosomal protein, large, P1 -0.0564753
RPS6 ribosomal protein S6 -0.0564377
RPL23 ribosomal protein L23 -0.0551026
CSTB cystatin B (stefin B) -0.0531552
PHF3 PHD finger protein 3 -0.05289
RPL34 ribosomal protein L34 -0.0525415
PGK1 phosphoglycerate kinase 1 -0.0517909
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0514543
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0487499
LOC112694756 uncharaterized LOC112694756 -0.0484599
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0476494
H1-0 H1.0 linker histone -0.0472314
IFI27 interferon, alpha-inducible protein 27 -0.0466519
AKAP9 A kinase (PRKA) anchor protein 9 -0.0466468
SLC38A1 solute carrier family 38, member 1 -0.0461554
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0452054
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0446379
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0440229
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0436635
RPS8 ribosomal protein S8 -0.0431884
PKM pyruvate kinase, muscle -0.0428618
WSB1 WD repeat and SOCS box containing 1 -0.0425365
PDIA3 protein disulfide isomerase family A, member 3 -0.0419543
TTC3 tetratricopeptide repeat domain 3 -0.0415567
HLA-C major histocompatibility complex, class I, C -0.0412402
EIF1 eukaryotic translation initiation factor 1 -0.0410983
FNDC3B fibronectin type III domain containing 3B -0.0404819
GCLC glutamate-cysteine ligase, catalytic subunit -0.0404521
WDR45B WD repeat domain 45B -0.0403258
RPL31 ribosomal protein L31 -0.0398451
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0398265
XAF1 XIAP associated factor 1 -0.0393232
DSTN destrin (actin depolymerizing factor) -0.0387451
RAB1A RAB1A, member RAS oncogene family -0.0386488
CALR calreticulin -0.038522
BPTF bromodomain PHD finger transcription factor -0.0385049
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0383449
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0383263
RHOBTB3 Rho-related BTB domain containing 3 -0.038296
RBM39 RNA binding motif protein 39 -0.038082
TMPRSS4 transmembrane protease, serine 4 -0.038003
ARF1 ADP-ribosylation factor 1 -0.0376093
PTBP3 polypyrimidine tract binding protein 3 -0.0372263
MBNL2 muscleblind-like splicing regulator 2 -0.0371755
PRKCA protein kinase C, alpha -0.0370618
ENO1 enolase 1, (alpha) -0.0369013
RPL37A ribosomal protein L37a -0.0368139
ACTG1 actin gamma 1 -0.0364147
RPLP2 ribosomal protein, large, P2 -0.0363168
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0363009
GOLGA4 golgin A4 -0.0361021
KRT19 keratin 19, type I -0.0360524
FNDC3A fibronectin type III domain containing 3A -0.0356663
RPL19 ribosomal protein L19 -0.0355136
RPS27 ribosomal protein S27 -0.0352319
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0351879
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0350299
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0349702
STAU1 staufen double-stranded RNA binding protein 1 -0.0348847
BTBD9 BTB (POZ) domain containing 9 -0.034119
NF1 neurofibromin 1 -0.0341178
BLZF1 basic leucine zipper nuclear factor 1 -0.0338564
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0333003
ZCCHC7 zinc finger, CCHC domain containing 7 -0.033282
ENO2 enolase 2 (gamma, neuronal) -0.0332514
RPS19 ribosomal protein S19 -0.0332154
SPDYA speedy/RINGO cell cycle regulator family member A -0.0331524
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0330964
PRRC2C proline-rich coiled-coil 2C -0.0329656