| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Meloxicam_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.118571 |
| PLEC | plectin | 0.0780617 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0755483 |
| FBN1 | fibrillin 1 | 0.0673439 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0621307 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0453814 |
| CANX | calnexin | 0.0383889 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383439 |
| AHNAK | AHNAK nucleoprotein | 0.0380426 |
| ARRDC3 | arrestin domain containing 3 | 0.0373403 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0338013 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0315926 |
| LOXL2 | lysyl oxidase-like 2 | 0.0307935 |
| VCAN | versican | 0.0306833 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0303789 |
| COL1A2 | collagen, type I, alpha 2 | 0.02834 |
| COL5A1 | collagen, type V, alpha 1 | 0.0281816 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0276749 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0255368 |
| APP | amyloid beta (A4) precursor protein | 0.0235358 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0234714 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.022322 |
| FAM20C | family with sequence similarity 20, member C | 0.0214425 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0210578 |
| DST | dystonin | 0.0210313 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0203737 |
| FAT1 | FAT atypical cadherin 1 | 0.0201637 |
| COL3A1 | collagen, type III, alpha 1 | 0.0201312 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0195363 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0193414 |
| CAVIN1 | caveolae associated protein 1 | 0.0189283 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0186011 |
| COL5A2 | collagen, type V, alpha 2 | 0.0177595 |
| TNS1 | tensin 1 | 0.0175263 |
| SMAD3 | SMAD family member 3 | 0.0171652 |
| LIPG | lipase, endothelial | 0.0170818 |
| MCL1 | myeloid cell leukemia 1 | 0.0170682 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0170045 |
| PFKP | phosphofructokinase, platelet | 0.0165105 |
| RPL3 | ribosomal protein L3 | 0.0162946 |
| AFAP1 | actin filament associated protein 1 | 0.0156389 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0154553 |
| YEATS2 | YEATS domain containing 2 | 0.0152823 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.0151959 |
| DSPP | dentin sialophosphoprotein | 0.0151762 |
| CCND1 | cyclin D1 | 0.0150788 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0148255 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0146969 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0143365 |
| MTSS1 | metastasis suppressor 1 | 0.0143142 |
| MLF1 | myeloid leukemia factor 1 | 0.0142537 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0136978 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0136898 |
| CALU | calumenin | 0.0134833 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0132102 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0131728 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0131705 |
| TPM4 | tropomyosin 4 | 0.0131652 |
| PLAU | plasminogen activator, urokinase | 0.0131131 |
| SULF1 | sulfatase 1 | 0.0128884 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0128602 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0127519 |
| TBX3 | T-box 3 | 0.0127392 |
| TMF1 | TATA element modulatory factor 1 | 0.0127339 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.01271 |
| USP34 | ubiquitin specific peptidase 34 | 0.0123688 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0123558 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.01233 |
| INHBA | inhibin, beta A | 0.0121315 |
| HDLBP | high density lipoprotein binding protein | 0.0120183 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0119418 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0117772 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0117556 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0117154 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0116337 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0116284 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0114516 |
| CMIP | c-Maf inducing protein | 0.0113496 |
| PLSCR1 | phospholipid scramblase 1 | 0.0112433 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0111302 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0111106 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0110372 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0110075 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0109926 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 0.0109745 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0109538 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0109102 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.010879 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0108335 |
| TNS3 | tensin 3 | 0.010707 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0106704 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0105812 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0105424 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0104165 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0104125 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0103878 |
| KIF5B | kinesin family member 5B | 0.0103559 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0103228 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0102625 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0101582 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.35266 |
| MT2A | metallothionein 2A | -0.350432 |
| TMSB10 | thymosin beta 10 | -0.185475 |
| NDRG1 | N-myc downstream regulated 1 | -0.18009 |
| VIM | vimentin | -0.159932 |
| FTL | ferritin, light polypeptide | -0.118313 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.110289 |
| RPS8 | ribosomal protein S8 | -0.0804933 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.069469 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0686731 |
| RPS19 | ribosomal protein S19 | -0.0667985 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0635978 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.062853 |
| RPL35A | ribosomal protein L35a | -0.0626522 |
| RPS6 | ribosomal protein S6 | -0.0590246 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0528708 |
| CD44 | CD44 molecule (Indian blood group) | -0.0525527 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0498832 |
| S100A9 | S100 calcium binding protein A9 | -0.0479919 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0474167 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0470955 |
| RPL28 | ribosomal protein L28 | -0.0459006 |
| PTMA | prothymosin, alpha | -0.0450833 |
| RPLP2 | ribosomal protein, large, P2 | -0.0450465 |
| ENO1 | enolase 1, (alpha) | -0.0444618 |
| HLA-B | major histocompatibility complex, class I, B | -0.0442647 |
| RPL37A | ribosomal protein L37a | -0.0440155 |
| RPL19 | ribosomal protein L19 | -0.043949 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0433691 |
| RPLP1 | ribosomal protein, large, P1 | -0.0430301 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0428992 |
| ACTG1 | actin gamma 1 | -0.0427237 |
| FN1 | fibronectin 1 | -0.0427228 |
| RPL12 | ribosomal protein L12 | -0.0422874 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.042207 |
| RPL11 | ribosomal protein L11 | -0.0414744 |
| RPL36 | ribosomal protein L36 | -0.0407547 |
| RPL23 | ribosomal protein L23 | -0.0393219 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0388238 |
| B2M | beta-2-microglobulin | -0.0378413 |
| RPL9 | ribosomal protein L9 | -0.0372721 |
| MT1X | metallothionein 1X | -0.0364728 |
| RPL8 | ribosomal protein L8 | -0.035439 |
| RPS14 | ribosomal protein S14 | -0.0350046 |
| RPS15 | ribosomal protein S15 | -0.0348704 |
| PFN1 | profilin 1 | -0.0348284 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0347843 |
| RPS23 | ribosomal protein S23 | -0.0342531 |
| EGR1 | early growth response 1 | -0.0339028 |
| RPL26 | ribosomal protein L26 | -0.0324688 |
| RPL37 | ribosomal protein L37 | -0.0323904 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0319591 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0319255 |
| RPL5 | ribosomal protein L5 | -0.0318225 |
| PKM | pyruvate kinase, muscle | -0.0317475 |
| RPL30 | ribosomal protein L30 | -0.0316212 |
| RPL34 | ribosomal protein L34 | -0.0312657 |
| RPS5 | ribosomal protein S5 | -0.0307135 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0302186 |
| RPS20 | ribosomal protein S20 | -0.0299869 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0296942 |
| RPL7 | ribosomal protein L7 | -0.0295829 |
| RPS13 | ribosomal protein S13 | -0.0290704 |
| RPS16 | ribosomal protein S16 | -0.0288235 |
| RPL32 | ribosomal protein L32 | -0.0288001 |
| S100A10 | S100 calcium binding protein A10 | -0.0287185 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0286346 |
| RPS21 | ribosomal protein S21 | -0.0284445 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0281133 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0280777 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0277002 |
| COL1A1 | collagen, type I, alpha 1 | -0.0275477 |
| RPS12 | ribosomal protein S12 | -0.0274227 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0271959 |
| RPL27 | ribosomal protein L27 | -0.0271383 |
| RTN4 | reticulon 4 | -0.0271255 |
| RPL31 | ribosomal protein L31 | -0.0269011 |
| HLA-A | major histocompatibility complex, class I, A | -0.0267676 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0266371 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259072 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0253997 |
| RPS17 | ribosomal protein S17 | -0.0252697 |
| SETD5 | SET domain containing 5 | -0.0251023 |
| FOSL1 | FOS-like antigen 1 | -0.0246514 |
| RPS10 | ribosomal protein S10 | -0.0242579 |
| CADM1 | cell adhesion molecule 1 | -0.0242138 |
| MTDH | metadherin | -0.0242109 |
| RPS11 | ribosomal protein S11 | -0.0240287 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0238906 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0237733 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.023609 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0235961 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.023534 |
| YBX1 | Y box binding protein 1 | -0.0231778 |
| RACK1 | receptor for activated C kinase 1 | -0.0231324 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.023119 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0229176 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0228754 |
| S100A6 | S100 calcium binding protein A6 | -0.022708 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0225867 |
