| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Meloxicam_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | 0.141927 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.137183 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.115451 |
| DSPP | dentin sialophosphoprotein | 0.105597 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0940361 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0825411 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0638401 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0621931 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0603545 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0555655 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0554425 |
| CFB | complement factor B | 0.0507471 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0488011 |
| ITGA1 | integrin, alpha 1 | 0.0480944 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476284 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0467108 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0464575 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0435741 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0421177 |
| C3 | complement component 3 | 0.0417787 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0406617 |
| PLEC | plectin | 0.0385985 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0370623 |
| MCL1 | myeloid cell leukemia 1 | 0.0361609 |
| GPC6 | glypican 6 | 0.0359638 |
| FOXP1 | forkhead box P1 | 0.034575 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0331035 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0328216 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0313132 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0309586 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0290224 |
| PEG3 | paternally expressed 3 | 0.0286756 |
| OSMR | oncostatin M receptor | 0.028399 |
| TMEM181 | transmembrane protein 181 | 0.0280666 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0276813 |
| TNS3 | tensin 3 | 0.0273252 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0271025 |
| SKI | SKI proto-oncogene | 0.0262422 |
| TF | transferrin | 0.0257398 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0253979 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0250282 |
| RELL1 | RELT-like 1 | 0.0247678 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0247585 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0246167 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0239394 |
| OAF | OAF homolog (Drosophila) | 0.0237384 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.023563 |
| SDC4 | syndecan 4 | 0.0235398 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0234451 |
| TCIM | transcriptional and immune response regulator | 0.022985 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0227722 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0224848 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0224466 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0224081 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0223763 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0217246 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.02155 |
| SEPTIN9 | septin 9 | 0.0214825 |
| SMAD3 | SMAD family member 3 | 0.0212942 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.021258 |
| RNF213 | ring finger protein 213 | 0.021113 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0209942 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0209288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0207665 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0204216 |
| EXT1 | exostosin glycosyltransferase 1 | 0.020297 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0201102 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.0199899 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0199298 |
| SYN3 | synapsin III | 0.0197417 |
| PLAC8 | placenta-specific 8 | 0.0196126 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0194147 |
| FILIP1L | filamin A interacting protein 1-like | 0.0189366 |
| CTSB | cathepsin B | 0.0189307 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0188018 |
| RIGI | RNA sensor RIG-I | 0.0187614 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0187391 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0187329 |
| ITGB5 | integrin, beta 5 | 0.0183421 |
| EGR1 | early growth response 1 | 0.0183017 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0182603 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0179882 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0177393 |
| CPE | carboxypeptidase E | 0.0176792 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0176402 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0176092 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0172975 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.017248 |
| IL4R | interleukin 4 receptor | 0.0172394 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0171913 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0171764 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0170675 |
| FGL1 | fibrinogen-like 1 | 0.0169666 |
| PLXDC2 | plexin domain containing 2 | 0.0169107 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.0167233 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0167128 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.016632 |
| HDAC4 | histone deacetylase 4 | 0.0164309 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.016332 |
| RPL3 | ribosomal protein L3 | 0.0163164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.421346 |
| MT2A | metallothionein 2A | -0.12604 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0994547 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0789696 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0664439 |
| HMGA1 | high mobility group AT-hook 1 | -0.0592915 |
| FTL | ferritin, light polypeptide | -0.0573161 |
| DTNA | dystrobrevin, alpha | -0.0565152 |
| NDRG1 | N-myc downstream regulated 1 | -0.0527706 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0513183 |
| APOA2 | apolipoprotein A-II | -0.0507863 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0485477 |
| TMSB10 | thymosin beta 10 | -0.0481331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0478701 |
| RPS6 | ribosomal protein S6 | -0.0441789 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0441464 |
| GOLGA4 | golgin A4 | -0.0415705 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0403029 |
| RPL11 | ribosomal protein L11 | -0.0393194 |
| RPL34 | ribosomal protein L34 | -0.0391559 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0382696 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.037925 |
| RPL35A | ribosomal protein L35a | -0.0372945 |
| INSIG2 | insulin induced gene 2 | -0.0358448 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0348587 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0341588 |
| RPL19 | ribosomal protein L19 | -0.0339013 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336398 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0335896 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.033151 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0328687 |
| PLIN2 | perilipin 2 | -0.0328226 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0326666 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.03208 |
| RPS24 | ribosomal protein S24 | -0.0318211 |
| RPS8 | ribosomal protein S8 | -0.0317022 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0315796 |
| WDR45B | WD repeat domain 45B | -0.031565 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.030718 |
| RBM39 | RNA binding motif protein 39 | -0.0304866 |
| HELZ | helicase with zinc finger | -0.0301998 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0300949 |
| RPS25 | ribosomal protein S25 | -0.0293596 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0284979 |
| ENO1 | enolase 1, (alpha) | -0.0284319 |
| FMNL2 | formin-like 2 | -0.0273874 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0270084 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0269283 |
| NPR2 | natriuretic peptide receptor 2 | -0.0268449 |
| RPS27A | ribosomal protein S27a | -0.0266372 |
| RPL37A | ribosomal protein L37a | -0.0265872 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.026561 |
| RPS3 | ribosomal protein S3 | -0.0261361 |
| TOP1 | topoisomerase (DNA) I | -0.0259103 |
| RPLP2 | ribosomal protein, large, P2 | -0.0256094 |
| RPL28 | ribosomal protein L28 | -0.0255293 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.025446 |
| VEGFA | vascular endothelial growth factor A | -0.0251469 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0248 |
| BRD4 | bromodomain containing 4 | -0.0247586 |
| RPS17 | ribosomal protein S17 | -0.0246446 |
| RPLP1 | ribosomal protein, large, P1 | -0.0246023 |
| ARFGEF3 | ARFGEF family member 3 | -0.0243269 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0242084 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0242025 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0240497 |
| WWC2 | WW and C2 domain containing 2 | -0.0240055 |
| RPL23 | ribosomal protein L23 | -0.023884 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.023843 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.023824 |
| SIK3 | SIK family kinase 3 | -0.023509 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.023457 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0234394 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0233623 |
| TBC1D22A | TBC1 domain family, member 22A | -0.023287 |
| RYBP | RING1 and YY1 binding protein | -0.0232323 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0231317 |
| RACK1 | receptor for activated C kinase 1 | -0.0231157 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0230522 |
| RPS21 | ribosomal protein S21 | -0.0229794 |
| MED13L | mediator complex subunit 13-like | -0.0228414 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0223867 |
| RPL12 | ribosomal protein L12 | -0.0223806 |
| SMAP1 | small ArfGAP 1 | -0.0220518 |
| BBX | bobby sox homolog (Drosophila) | -0.0219845 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0215969 |
| RPL8 | ribosomal protein L8 | -0.021351 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.021334 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0212312 |
| APOA1 | apolipoprotein A-I | -0.0212168 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0210805 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0209573 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.020898 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0207794 |
| QKI | QKI, KH domain containing, RNA binding | -0.0207538 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0204859 |
| NFIA | nuclear factor I/A | -0.0204462 |
| RPS29 | ribosomal protein S29 | -0.0204238 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0201859 |
| VCL | vinculin | -0.0201172 |
