| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Meloxicam_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.280252 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.116344 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.111233 |
| PLEC | plectin | 0.102328 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0693999 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0665938 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0652429 |
| EGFR | epidermal growth factor receptor | 0.0617723 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0616075 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0608813 |
| EFNA5 | ephrin-A5 | 0.0549133 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.052629 |
| LAMC2 | laminin, gamma 2 | 0.052492 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0511986 |
| CPE | carboxypeptidase E | 0.0510565 |
| ASPH | aspartate beta-hydroxylase | 0.0488843 |
| LDHA | lactate dehydrogenase A | 0.0472429 |
| RNF213 | ring finger protein 213 | 0.0451608 |
| LMO7 | LIM domain 7 | 0.0431365 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0419379 |
| B2M | beta-2-microglobulin | 0.0411241 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0406464 |
| CCND1 | cyclin D1 | 0.0396607 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0396507 |
| DSPP | dentin sialophosphoprotein | 0.0378964 |
| LAMA4 | laminin, alpha 4 | 0.0373036 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.037259 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0370897 |
| MCL1 | myeloid cell leukemia 1 | 0.0362004 |
| FOXP1 | forkhead box P1 | 0.0361641 |
| KRT7 | keratin 7, type II | 0.0359205 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0335167 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0325907 |
| KRT18 | keratin 18, type I | 0.0312859 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0311189 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.03105 |
| OSMR | oncostatin M receptor | 0.0307802 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0306447 |
| KYNU | kynureninase | 0.0302427 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.029459 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0293426 |
| AREG | amphiregulin | 0.0292195 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0291831 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0289682 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0287918 |
| CAV2 | caveolin 2 | 0.0286579 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0281834 |
| MYOF | myoferlin | 0.0275522 |
| CTSL | cathepsin L | 0.0274858 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0273443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.027054 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0266828 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0262601 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261484 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0255799 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0247 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0246148 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0245747 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0241866 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0236821 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0236524 |
| GRAMD1B | GRAM domain containing 1B | 0.0235003 |
| SMAD3 | SMAD family member 3 | 0.0232502 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0231387 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0228264 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0224936 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0224707 |
| CST3 | cystatin C | 0.022122 |
| RHOV | ras homolog family member V | 0.0217306 |
| ANXA2 | annexin A2 | 0.021609 |
| TNS3 | tensin 3 | 0.0213943 |
| EGR1 | early growth response 1 | 0.0213006 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0212237 |
| LAMB3 | laminin, beta 3 | 0.0208498 |
| SDC1 | syndecan 1 | 0.0208229 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0206874 |
| DST | dystonin | 0.0204979 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0203962 |
| STC2 | stanniocalcin 2 | 0.0203554 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0203535 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0202911 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0198435 |
| AHR | aryl hydrocarbon receptor | 0.0197612 |
| SLTM | SAFB-like, transcription modulator | 0.0197522 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0196854 |
| RAB10 | RAB10, member RAS oncogene family | 0.0196782 |
| RBM47 | RNA binding motif protein 47 | 0.019502 |
| S100A11 | S100 calcium binding protein A11 | 0.0194479 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.019145 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0191443 |
| SMIM14 | small integral membrane protein 14 | 0.0190052 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0189952 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0189094 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0186717 |
| MYO1E | myosin IE | 0.0184807 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0182899 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0182784 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0182425 |
| MX1 | MX dynamin-like GTPase 1 | 0.0181777 |
| SEPTIN9 | septin 9 | 0.0181543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.47231 |
| UBC | ubiquitin C | -0.131892 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0885211 |
| FAM13A | family with sequence similarity 13, member A | -0.0680999 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0653634 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0629892 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0612887 |
| NGLY1 | N-glycanase 1 | -0.0609955 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0585905 |
| RPS27A | ribosomal protein S27a | -0.0578202 |
| DTNA | dystrobrevin, alpha | -0.0565282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.054511 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.05319 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0531325 |
| PTMA | prothymosin, alpha | -0.0529194 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0518656 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0492777 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0485652 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0473692 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0461515 |
| HELZ | helicase with zinc finger | -0.0447412 |
| SPAG9 | sperm associated antigen 9 | -0.0444884 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.044402 |
| OGA | O-GlcNAcase | -0.0415739 |
| UVRAG | UV radiation resistance associated | -0.0415276 |
| RUNX1 | runt-related transcription factor 1 | -0.04129 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0409575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0398105 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0392828 |
| SEPTIN2 | septin 2 | -0.0392472 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0384051 |
| RPLP1 | ribosomal protein, large, P1 | -0.038178 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0379165 |
| FTL | ferritin, light polypeptide | -0.0377852 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0377171 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0370561 |
| MT2A | metallothionein 2A | -0.0368382 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0361564 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0361153 |
| MORF4L2 | mortality factor 4 like 2 | -0.0359711 |
| JMJD1C | jumonji domain containing 1C | -0.0359122 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0357538 |
| WDR45B | WD repeat domain 45B | -0.0349237 |
| TMSB10 | thymosin beta 10 | -0.0347214 |
| RPS8 | ribosomal protein S8 | -0.0346639 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0345761 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0344636 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0340601 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0336684 |
| TPD52 | tumor protein D52 | -0.0335738 |
| NDRG1 | N-myc downstream regulated 1 | -0.0335393 |
| FNIP1 | folliculin interacting protein 1 | -0.0329194 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0327249 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0324799 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0322409 |
| SRP54 | signal recognition particle 54kDa | -0.0320184 |
| TMEM165 | transmembrane protein 165 | -0.031547 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0310294 |
| RPL37A | ribosomal protein L37a | -0.0308632 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0302318 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0298003 |
| RPS3 | ribosomal protein S3 | -0.0296706 |
| NF1 | neurofibromin 1 | -0.0296646 |
| SEC61G | Sec61 gamma subunit | -0.0294701 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0293056 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0291701 |
| SUCO | SUN domain containing ossification factor | -0.02903 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0289651 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0286517 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0285638 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0283426 |
| PDE8A | phosphodiesterase 8A | -0.0282164 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0277145 |
| RASA2 | RAS p21 protein activator 2 | -0.0276853 |
| MED13 | mediator complex subunit 13 | -0.0275244 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0274474 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0272352 |
| MKI67 | marker of proliferation Ki-67 | -0.0271588 |
| ATP13A3 | ATPase type 13A3 | -0.0271377 |
| CUL4A | cullin 4A | -0.0269838 |
| TOP1 | topoisomerase (DNA) I | -0.0266759 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0266137 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.02655 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.026166 |
| H1-0 | H1.0 linker histone | -0.0260382 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0259953 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0259815 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0259271 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.025818 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257623 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0255992 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0254775 |
| CUL3 | cullin 3 | -0.0254374 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0253678 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0250992 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0250303 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0248727 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0246188 |
| ZNF292 | zinc finger protein 292 | -0.0245289 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0242882 |
