| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Meloxicam_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.21402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.14062 |
| GRB10 | growth factor receptor-bound protein 10 | 0.121185 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111068 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.105445 |
| GPC6 | glypican 6 | 0.105101 |
| VGF | VGF nerve growth factor inducible | 0.104595 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.100431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0956718 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0931402 |
| RIGI | RNA sensor RIG-I | 0.0908854 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0832574 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0812745 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0803857 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0752601 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0751487 |
| LAMA4 | laminin, alpha 4 | 0.073885 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0717085 |
| LDHA | lactate dehydrogenase A | 0.0685994 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0676902 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0663662 |
| FAM13A | family with sequence similarity 13, member A | 0.0649102 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0645679 |
| SSH2 | slingshot protein phosphatase 2 | 0.0632088 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0596476 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0587039 |
| CANX | calnexin | 0.0585234 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.058381 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0568661 |
| CALU | calumenin | 0.0565564 |
| PCBP2 | poly(rC) binding protein 2 | 0.0554667 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0545319 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.053254 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0526423 |
| NUP58 | nucleoporin 58 | 0.0525037 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.052267 |
| PTEN | phosphatase and tensin homolog | 0.0517798 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0514954 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0514569 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.051317 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0505888 |
| PDE10A | phosphodiesterase 10A | 0.0493086 |
| TOP1 | topoisomerase (DNA) I | 0.0490545 |
| MATR3 | matrin 3 | 0.048231 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.048191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0476559 |
| NGLY1 | N-glycanase 1 | 0.0473207 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0469536 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0466035 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0465943 |
| ZNF292 | zinc finger protein 292 | 0.0452588 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0452328 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0447032 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0434815 |
| XPO1 | exportin 1 | 0.0433196 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0430833 |
| MXD1 | MAX dimerization protein 1 | 0.0424754 |
| PRELID2 | PRELI domain containing 2 | 0.04214 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0417206 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.0412325 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0412174 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0411403 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0404999 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.040308 |
| PDE8A | phosphodiesterase 8A | 0.0402566 |
| SPAG9 | sperm associated antigen 9 | 0.0402295 |
| RORA | RAR-related orphan receptor A | 0.0395691 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0395565 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0394523 |
| COG5 | component of oligomeric golgi complex 5 | 0.0394116 |
| CEP350 | centrosomal protein 350kDa | 0.0393641 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.039128 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0391124 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.038356 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.03762 |
| SRPK2 | SRSF protein kinase 2 | 0.036943 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.036339 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360757 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0358564 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0355878 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0353194 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0351203 |
| PGK1 | phosphoglycerate kinase 1 | 0.0338911 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.033834 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0336986 |
| COLEC11 | collectin sub-family member 11 | 0.0336457 |
| COL1A2 | collagen, type I, alpha 2 | 0.0333326 |
| TMEM178B | transmembrane protein 178B | 0.0333301 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0333171 |
| RCOR1 | REST corepressor 1 | 0.0331434 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331084 |
| NBEAL1 | neurobeachin-like 1 | 0.0330675 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0329505 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0323846 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0323442 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0317752 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 0.0317726 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0317198 |
| RUNX1 | runt-related transcription factor 1 | 0.0316833 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0315854 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216988 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.199092 |
| LMO7 | LIM domain 7 | -0.188209 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.127761 |
| MT2A | metallothionein 2A | -0.121414 |
| IGF2 | insulin-like growth factor 2 | -0.114495 |
| ANXA2 | annexin A2 | -0.113531 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.112856 |
| MYO1E | myosin IE | -0.096055 |
| RNF213 | ring finger protein 213 | -0.0911791 |
| POTEF | POTE ankyrin domain family, member F | -0.0881282 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0842553 |
| TMSB10 | thymosin beta 10 | -0.0841701 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0838856 |
| LAMC2 | laminin, gamma 2 | -0.0822326 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.080709 |
| SLC38A1 | solute carrier family 38, member 1 | -0.078371 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0778609 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0750694 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0745861 |
| ERBIN | erbb2 interacting protein | -0.0742882 |
| RBM47 | RNA binding motif protein 47 | -0.0741863 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.074082 |
| SVIL | supervillin | -0.0727061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0696979 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0696753 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0694853 |
| VIM | vimentin | -0.0686757 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0683645 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0680095 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0677426 |
| ATOSA | atos homolog A | -0.0644123 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0641378 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.062916 |
| TXNIP | thioredoxin interacting protein | -0.059562 |
| S100A10 | S100 calcium binding protein A10 | -0.0592767 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0591497 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0591073 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0589001 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0572473 |
| GLIS3 | GLIS family zinc finger 3 | -0.0549436 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0543687 |
| LAMB3 | laminin, beta 3 | -0.054346 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0541578 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0530433 |
| CD44 | CD44 molecule (Indian blood group) | -0.0528264 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0513877 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0502346 |
| S100A9 | S100 calcium binding protein A9 | -0.0501669 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0499837 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0492374 |
| DSG2 | desmoglein 2 | -0.0483153 |
| RRBP1 | ribosome binding protein 1 | -0.0477471 |
| FMN1 | formin 1 | -0.0475388 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0469684 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0468002 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0461339 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0460586 |
| RPS16 | ribosomal protein S16 | -0.0458497 |
| S100A6 | S100 calcium binding protein A6 | -0.0456356 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0450079 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0445755 |
| AHNAK | AHNAK nucleoprotein | -0.0442189 |
| EFNA5 | ephrin-A5 | -0.0441743 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0439257 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0434683 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0433726 |
| OSMR | oncostatin M receptor | -0.04309 |
| BBX | bobby sox homolog (Drosophila) | -0.0425124 |
| LOXL2 | lysyl oxidase-like 2 | -0.041432 |
| BPTF | bromodomain PHD finger transcription factor | -0.0411315 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0401213 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0399328 |
| FBXO11 | F-box protein 11 | -0.0398656 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0395962 |
| RAB10 | RAB10, member RAS oncogene family | -0.0385378 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0373333 |
| VCL | vinculin | -0.0372381 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0367982 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0363414 |
| TMEM87A | transmembrane protein 87A | -0.0351517 |
| H3-3B | H3.3 histone B | -0.0350236 |
| FNIP1 | folliculin interacting protein 1 | -0.0338588 |
| CCND1 | cyclin D1 | -0.0335877 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0334438 |
| B2M | beta-2-microglobulin | -0.0328168 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0326369 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0324419 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0304947 |
| HLA-B | major histocompatibility complex, class I, B | -0.0297914 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0291697 |
| SMAD3 | SMAD family member 3 | -0.0291495 |
| PRKCA | protein kinase C, alpha | -0.0288552 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0286183 |
| RPS14 | ribosomal protein S14 | -0.0282484 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0280201 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0277406 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0276543 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0276188 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273793 |
