| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Meloxicam_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0548127 |
| GDA | guanine deaminase | 0.0542041 |
| TXNRD1 | thioredoxin reductase 1 | 0.0429161 |
| GRAMD1B | GRAM domain containing 1B | 0.0352641 |
| NEK7 | NIMA-related kinase 7 | 0.0337717 |
| KYNU | kynureninase | 0.0296849 |
| ASPH | aspartate beta-hydroxylase | 0.0261411 |
| DST | dystonin | 0.0259014 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0252333 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.024172 |
| EFNA5 | ephrin-A5 | 0.0234005 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0218699 |
| PTEN | phosphatase and tensin homolog | 0.0214646 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0208521 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.019407 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0194036 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0193571 |
| INTS6 | integrator complex subunit 6 | 0.0193395 |
| VCL | vinculin | 0.0183143 |
| TNPO1 | transportin 1 | 0.0178792 |
| ENAH | enabled homolog (Drosophila) | 0.0178406 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0167831 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0166705 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0161351 |
| RPL3 | ribosomal protein L3 | 0.0159168 |
| MED13L | mediator complex subunit 13-like | 0.015653 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0146527 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.014614 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0144732 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0130863 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0129571 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0128242 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0127903 |
| PLEC | plectin | 0.0126914 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0126336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0125789 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.012514 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0123624 |
| PLCB4 | phospholipase C, beta 4 | 0.0120611 |
| HDAC4 | histone deacetylase 4 | 0.011809 |
| PTK2 | protein tyrosine kinase 2 | 0.011353 |
| SETX | senataxin | 0.0110054 |
| GPHN | gephyrin | 0.01092 |
| METTL15 | methyltransferase like 15 | 0.0106552 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0106148 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0105625 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0104958 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0103301 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0102272 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0102096 |
| EXOC4 | exocyst complex component 4 | 0.0100471 |
| TUSC3 | tumor suppressor candidate 3 | 0.00991125 |
| EXOC6B | exocyst complex component 6B | 0.00990483 |
| CTSC | cathepsin C | 0.00980076 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.00972068 |
| NABP1 | nucleic acid binding protein 1 | 0.00961251 |
| WDR43 | WD repeat domain 43 | 0.00957326 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00944884 |
| PKP4 | plakophilin 4 | 0.00924628 |
| SELENOI | selenoprotein I | 0.00919588 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0091886 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.00916853 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00915146 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0089928 |
| PCNX2 | pecanex 2 | 0.00893971 |
| IPO7 | importin 7 | 0.00891533 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.00887699 |
| PHF14 | PHD finger protein 14 | 0.0087305 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0086588 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.00864497 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.00860254 |
| MED13 | mediator complex subunit 13 | 0.00846086 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0084202 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00838583 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.00826724 |
| ZNF207 | zinc finger protein 207 | 0.00820741 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.00807518 |
| CCDC138 | coiled-coil domain containing 138 | 0.00806073 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00805709 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.00802318 |
| GLCCI1 | glucocorticoid induced 1 | 0.00801102 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00800705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00800277 |
| EVI5 | ecotropic viral integration site 5 | 0.00790207 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00782514 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00781298 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.00779773 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00779529 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00779319 |
| PSPC1 | paraspeckle component 1 | 0.00776496 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.00776468 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00767851 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.00767401 |
| NCKAP1 | NCK-associated protein 1 | 0.00766877 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00766802 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00766364 |
| KIFC3 | kinesin family member C3 | 0.00763195 |
| FANCL | Fanconi anemia, complementation group L | 0.00761857 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0075943 |
| MEMO1 | mediator of cell motility 1 | 0.00758351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.324038 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.262472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.174636 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.169882 |
| VIM | vimentin | -0.109719 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0977243 |
| TMSB10 | thymosin beta 10 | -0.0812433 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0702467 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.062084 |
| FTL | ferritin, light polypeptide | -0.0615563 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0594092 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0591427 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.058499 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.056793 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0521584 |
| SPAG9 | sperm associated antigen 9 | -0.0510958 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0508294 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.050389 |
| CANX | calnexin | -0.0499307 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0493175 |
| S100A6 | S100 calcium binding protein A6 | -0.0492089 |
| RPS6 | ribosomal protein S6 | -0.0477848 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0472553 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.047086 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0470675 |
| GNAS | GNAS complex locus | -0.0467953 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0461534 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0460367 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.045982 |
| COL5A2 | collagen, type V, alpha 2 | -0.0450739 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0450007 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0446647 |
| STC1 | stanniocalcin 1 | -0.0440976 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426811 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0418791 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413768 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0408148 |
| RGS2 | regulator of G-protein signaling 2 | -0.0407673 |
| PGK1 | phosphoglycerate kinase 1 | -0.0403561 |
| MAP7 | microtubule-associated protein 7 | -0.0397063 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0394589 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0386589 |
| MYOF | myoferlin | -0.0386138 |
| B2M | beta-2-microglobulin | -0.0381282 |
| ENO1 | enolase 1, (alpha) | -0.0380486 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.037346 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0352629 |
| LSAMP | limbic system-associated membrane protein | -0.0350337 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.034106 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0340363 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0339262 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.033454 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.03333 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0327722 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0324841 |
| CDH13 | cadherin 13 | -0.0319486 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0313865 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0311528 |
| PTMA | prothymosin, alpha | -0.0311343 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0306114 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0302346 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299738 |
| NDRG1 | N-myc downstream regulated 1 | -0.029966 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0297787 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0295872 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.029385 |
| RPL26 | ribosomal protein L26 | -0.0292844 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0291236 |
| RPLP0 | ribosomal protein, large, P0 | -0.029035 |
| FAM13A | family with sequence similarity 13, member A | -0.0289943 |
| RPS3 | ribosomal protein S3 | -0.0289586 |
| INHBA | inhibin, beta A | -0.0289344 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0287441 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0286562 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0286175 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0283276 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0276461 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0272967 |
| MT2A | metallothionein 2A | -0.0272195 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0270292 |
| YBX3 | Y box binding protein 3 | -0.0270192 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0267445 |
| TENM3 | teneurin transmembrane protein 3 | -0.0267072 |
| RPL12 | ribosomal protein L12 | -0.0265514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265391 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264931 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0261479 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0259197 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0257567 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0256883 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0254953 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.025387 |
| IER3 | immediate early response 3 | -0.0251398 |
| EGR1 | early growth response 1 | -0.0250454 |
| IL6 | interleukin 6 | -0.0243293 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0243112 |
| LDHA | lactate dehydrogenase A | -0.0237966 |
| TMSB4X | thymosin beta 4, X-linked | -0.0232232 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0232138 |
| RPL19 | ribosomal protein L19 | -0.0231598 |
