| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Meloxicam_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.14818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.138833 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.138492 |
| INHBA | inhibin, beta A | 0.138367 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.13403 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.121799 |
| EGFR | epidermal growth factor receptor | 0.112891 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.112737 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.111849 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.101698 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.100937 |
| USP34 | ubiquitin specific peptidase 34 | 0.0936954 |
| PDE10A | phosphodiesterase 10A | 0.0918797 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0831554 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0814602 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0795452 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0777596 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0773261 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0759616 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0718436 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0691187 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0673281 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.060842 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0602394 |
| PDS5A | PDS5 cohesin associated factor A | 0.0601956 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0578668 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0573318 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.0559148 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0555685 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0555383 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0551786 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0550608 |
| ZNF654 | zinc finger protein 654 | 0.0537463 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0530134 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0524773 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0518995 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0512418 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0512288 |
| RHEB | Ras homolog enriched in brain | 0.0508003 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.050145 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.047773 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0465274 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0453811 |
| VIM | vimentin | 0.0441488 |
| GOLGA4 | golgin A4 | 0.0441328 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0434934 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0425002 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0419515 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0408992 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0405845 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0401799 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.039699 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0389779 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.038139 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0375392 |
| PKM | pyruvate kinase, muscle | 0.0372576 |
| ASPH | aspartate beta-hydroxylase | 0.0364159 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0353424 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0342477 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0340389 |
| SMAD3 | SMAD family member 3 | 0.0338304 |
| MED13 | mediator complex subunit 13 | 0.033522 |
| SETD5 | SET domain containing 5 | 0.0334046 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0333602 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0319684 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0318813 |
| PDE8A | phosphodiesterase 8A | 0.0318705 |
| ZNF148 | zinc finger protein 148 | 0.0316217 |
| FTL | ferritin, light polypeptide | 0.030823 |
| USP53 | ubiquitin specific peptidase 53 | 0.0295728 |
| GPC6 | glypican 6 | 0.0282403 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0260453 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0247802 |
| NFIA | nuclear factor I/A | 0.0236612 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.02344 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0234301 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0228446 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0216471 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0215372 |
| ENO1 | enolase 1, (alpha) | 0.021442 |
| HELZ | helicase with zinc finger | 0.021107 |
| TPI1 | triosephosphate isomerase 1 | 0.0198975 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.017609 |
| DST | dystonin | 0.0170666 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0163314 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0159004 |
| ZNF292 | zinc finger protein 292 | 0.0149868 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0140265 |
| NUP58 | nucleoporin 58 | 0.013986 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0130006 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0126712 |
| RPL37A | ribosomal protein L37a | 0.0126337 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0119358 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0113186 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0108335 |
| MYO9B | myosin IXB | 0.0101433 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00931661 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00906289 |
| ANKRD17 | ankyrin repeat domain 17 | 0.00890306 |
| MT2A | metallothionein 2A | 0.00859253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261071 |
| PTMA | prothymosin, alpha | -0.155731 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.134411 |
| UBC | ubiquitin C | -0.128918 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.123749 |
| SNX9 | sorting nexin 9 | -0.101308 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.100362 |
| ANXA2 | annexin A2 | -0.092196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0890524 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0874306 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.085352 |
| RPLP1 | ribosomal protein, large, P1 | -0.082627 |
| LMO7 | LIM domain 7 | -0.0815139 |
| RPL23 | ribosomal protein L23 | -0.0802301 |
| ITGA6 | integrin, alpha 6 | -0.0798432 |
| TMSB10 | thymosin beta 10 | -0.0796455 |
| RPS16 | ribosomal protein S16 | -0.0729706 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0725083 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0657509 |
| PGK1 | phosphoglycerate kinase 1 | -0.0656645 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.065636 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0652284 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0650106 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0631217 |
| RPS3 | ribosomal protein S3 | -0.0611612 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0611285 |
| STAG2 | stromal antigen 2 | -0.0609743 |
| SP100 | SP100 nuclear antigen | -0.0599932 |
| MAP4 | microtubule-associated protein 4 | -0.057315 |
| LAMB3 | laminin, beta 3 | -0.0562098 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0560475 |
| RLF | rearranged L-myc fusion | -0.0556565 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0556425 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0538728 |
| RPLP2 | ribosomal protein, large, P2 | -0.0534077 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0527548 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0525421 |
| FLNB | filamin B, beta | -0.0519017 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0516404 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0509771 |
| RPS8 | ribosomal protein S8 | -0.0503501 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0497859 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0484792 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0480004 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0459797 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0454866 |
| RBM25 | RNA binding motif protein 25 | -0.0445882 |
| SPATA13 | spermatogenesis associated 13 | -0.0431431 |
| NAV2 | neuron navigator 2 | -0.0423121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0410276 |
| JMJD1C | jumonji domain containing 1C | -0.0405763 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0402805 |
| RTN4 | reticulon 4 | -0.0397107 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0392074 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0379228 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0375388 |
| EGR1 | early growth response 1 | -0.0362683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0357791 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0351636 |
| PTK2 | protein tyrosine kinase 2 | -0.0349572 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.034648 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0332187 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322103 |
| RPS6 | ribosomal protein S6 | -0.0317846 |
| WASF2 | WAS protein family, member 2 | -0.0311501 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0310244 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0308505 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0301664 |
| RPL37 | ribosomal protein L37 | -0.028828 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0278769 |
| MYOF | myoferlin | -0.0271432 |
| ACTG1 | actin gamma 1 | -0.0257545 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0252978 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0251679 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0245266 |
| FN1 | fibronectin 1 | -0.0241082 |
| RPL31 | ribosomal protein L31 | -0.0222218 |
| ACTN4 | actinin, alpha 4 | -0.0210741 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0205409 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0199475 |
| CDK6 | cyclin-dependent kinase 6 | -0.0197866 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0194756 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0179169 |
| LDHA | lactate dehydrogenase A | -0.0177029 |
| MCL1 | myeloid cell leukemia 1 | -0.0174738 |
| PARD3 | par-3 family cell polarity regulator | -0.017383 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0173811 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0164628 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.016071 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0157238 |
| MXD1 | MAX dimerization protein 1 | -0.0145017 |
| SRPK2 | SRSF protein kinase 2 | -0.0136269 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0132967 |
| NDRG1 | N-myc downstream regulated 1 | -0.0127938 |
| RPL26 | ribosomal protein L26 | -0.0124928 |
| NF1 | neurofibromin 1 | -0.012392 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0119869 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0113223 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0112235 |
| COG5 | component of oligomeric golgi complex 5 | -0.0110473 |
