| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Meloxicam perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Meloxicam_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0447673 |
| MCL1 | myeloid cell leukemia 1 | 0.0403456 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.038234 |
| INTS6 | integrator complex subunit 6 | 0.0377506 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0369405 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0344071 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0343379 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0316657 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0300165 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0298804 |
| CPNE1 | copine I | 0.0287485 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0278226 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0271943 |
| GOLGB1 | golgin B1 | 0.0269212 |
| NPTN | neuroplastin | 0.02678 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0264957 |
| GOLGA2 | golgin A2 | 0.0260731 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0243363 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0243295 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0241921 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0234201 |
| PLEC | plectin | 0.0231289 |
| COG6 | component of oligomeric golgi complex 6 | 0.0225597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0217876 |
| CALU | calumenin | 0.0217636 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0216752 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0214695 |
| RPL23 | ribosomal protein L23 | 0.0209243 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.020831 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0208234 |
| KIF1B | kinesin family member 1B | 0.0206608 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.0205992 |
| RPL3 | ribosomal protein L3 | 0.0199102 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0196556 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0195905 |
| EXT1 | exostosin glycosyltransferase 1 | 0.019572 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0192782 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0191265 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0189179 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0188568 |
| YBX1 | Y box binding protein 1 | 0.0187595 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0187125 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0186005 |
| MORF4L2 | mortality factor 4 like 2 | 0.0184891 |
| CEP192 | centrosomal protein 192kDa | 0.0184217 |
| COG5 | component of oligomeric golgi complex 5 | 0.0183701 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0181476 |
| ZNF451 | zinc finger protein 451 | 0.0181117 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0178834 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0175616 |
| PNN | pinin, desmosome associated protein | 0.017131 |
| NABP1 | nucleic acid binding protein 1 | 0.0168597 |
| R3HDM2 | R3H domain containing 2 | 0.0168542 |
| ASPH | aspartate beta-hydroxylase | 0.0168406 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.016812 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0165992 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0164049 |
| CRTAP | cartilage associated protein | 0.016258 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0162228 |
| FANCC | Fanconi anemia, complementation group C | 0.0159966 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0159946 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0159573 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0159182 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.0159108 |
| SENP1 | SUMO1/sentrin specific peptidase 1 | 0.0158923 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0158806 |
| TAOK1 | TAO kinase 1 | 0.0158443 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0158372 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158067 |
| GAK | cyclin G associated kinase | 0.0156395 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0156093 |
| RO60 | Ro60, Y RNA binding protein | 0.0156054 |
| MELTF | melanotransferrin | 0.0155982 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0155687 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0154689 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.015239 |
| TULP3 | tubby like protein 3 | 0.0151961 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0150047 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | 0.0149221 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0148113 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0146568 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0145993 |
| SELENOI | selenoprotein I | 0.0145468 |
| CCNL1 | cyclin L1 | 0.0145139 |
| DBF4B | DBF4 zinc finger B | 0.0143938 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0143588 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.014351 |
| TPD52L2 | tumor protein D52-like 2 | 0.0142648 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0141864 |
| RPL9 | ribosomal protein L9 | 0.0141612 |
| CIP2A | cellular inhibitor of PP2A | 0.0139249 |
| CREM | cAMP responsive element modulator | 0.0138985 |
| SYF2 | SYF2 pre-mRNA-splicing factor | 0.0138899 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0138647 |
| SLFN11 | schlafen family member 11 | 0.0138608 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.0138416 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0137935 |
| ERGIC3 | ERGIC and golgi 3 | 0.0137868 |
| PTEN | phosphatase and tensin homolog | 0.0137827 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0137507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180691 |
| FNDC3B | fibronectin type III domain containing 3B | -0.155831 |
| VIM | vimentin | -0.0928393 |
| TMSB10 | thymosin beta 10 | -0.0922497 |
| LDHA | lactate dehydrogenase A | -0.0806233 |
| PRKCA | protein kinase C, alpha | -0.0789706 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0771488 |
| CD44 | CD44 molecule (Indian blood group) | -0.0768417 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0744357 |
| PTMA | prothymosin, alpha | -0.0701164 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0636795 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0589822 |
| ANXA2 | annexin A2 | -0.0551304 |
| IER3 | immediate early response 3 | -0.0533923 |
| PKM | pyruvate kinase, muscle | -0.0525956 |
| SVIL | supervillin | -0.0515551 |
| AHNAK | AHNAK nucleoprotein | -0.0508673 |
| FMNL2 | formin-like 2 | -0.0502379 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0499155 |
| YBX3 | Y box binding protein 3 | -0.0490402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0485761 |
| HMGA2 | high mobility group AT-hook 2 | -0.0472352 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.046676 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0457914 |
| NAV2 | neuron navigator 2 | -0.0452593 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0451629 |
| DST | dystonin | -0.0432874 |
| PTK2 | protein tyrosine kinase 2 | -0.0416402 |
| IGF2 | insulin-like growth factor 2 | -0.0401741 |
| RBM39 | RNA binding motif protein 39 | -0.0393618 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0373519 |
| JAK1 | Janus kinase 1 | -0.0372276 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0367418 |
| PARD3 | par-3 family cell polarity regulator | -0.0363946 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0363609 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0361899 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0361074 |
| SPAG9 | sperm associated antigen 9 | -0.035742 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0351801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034969 |
| ATXN1 | ataxin 1 | -0.0349357 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0346738 |
| SMYD3 | SET and MYND domain containing 3 | -0.0344434 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0343515 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0342465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0342008 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0340533 |
| DEK | DEK proto-oncogene | -0.0333526 |
| VCL | vinculin | -0.0333518 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0331879 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0330526 |
| FMN1 | formin 1 | -0.0327546 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0326711 |
| RIGI | RNA sensor RIG-I | -0.0323386 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308506 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0302209 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300165 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0298525 |
| POTEF | POTE ankyrin domain family, member F | -0.0298371 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0295707 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0291492 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0291214 |
| BBX | bobby sox homolog (Drosophila) | -0.0290555 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0283414 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0281946 |
| PRR16 | proline rich 16 | -0.0280355 |
| IL6ST | interleukin 6 signal transducer | -0.0278997 |
| FLNB | filamin B, beta | -0.0277515 |
| OGA | O-GlcNAcase | -0.0271434 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0270454 |
| ANGPTL4 | angiopoietin-like 4 | -0.0270381 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0268897 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0267861 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0264214 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0263458 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0262677 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0261257 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0260674 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0260224 |
| CANX | calnexin | -0.0259119 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0258891 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0258835 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0258709 |
| TCF12 | transcription factor 12 | -0.0257223 |
| CYTH1 | cytohesin 1 | -0.0256758 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0256 |
| MAP1B | microtubule-associated protein 1B | -0.0255901 |
| RORA | RAR-related orphan receptor A | -0.0253967 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0253962 |
| PFN1 | profilin 1 | -0.0251704 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0251377 |
| COL5A1 | collagen, type V, alpha 1 | -0.0248981 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0247701 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0247465 |
| RNF145 | ring finger protein 145 | -0.0246703 |
| RTN4 | reticulon 4 | -0.0244564 |
| HLA-A | major histocompatibility complex, class I, A | -0.0244178 |
| ERBIN | erbb2 interacting protein | -0.024319 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0242818 |
| PHIP | pleckstrin homology domain interacting protein | -0.024156 |
