| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.120251 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.114894 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0995056 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0774518 |
| TMSB10 | thymosin beta 10 | 0.0728789 |
| CPOX | coproporphyrinogen oxidase | 0.0724679 |
| XPO1 | exportin 1 | 0.0691608 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0669879 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0639203 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0601264 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0599714 |
| CCNL1 | cyclin L1 | 0.0597352 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0560764 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0533819 |
| VMP1 | vacuole membrane protein 1 | 0.052767 |
| TMEM41B | transmembrane protein 41B | 0.0519263 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0510003 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0506518 |
| NCKAP1 | NCK-associated protein 1 | 0.0505529 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0501311 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0494582 |
| PCBP2 | poly(rC) binding protein 2 | 0.0493583 |
| TFG | TRK-fused gene | 0.0482696 |
| RPS23 | ribosomal protein S23 | 0.0469165 |
| AHR | aryl hydrocarbon receptor | 0.0463633 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0461957 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045454 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0453938 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0451849 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0437346 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0432898 |
| NRXN3 | neurexin 3 | 0.0431085 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0420414 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0418695 |
| NEGR1 | neuronal growth regulator 1 | 0.0412071 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0410079 |
| NEK7 | NIMA-related kinase 7 | 0.0404653 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0399533 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0399462 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0399379 |
| POTEF | POTE ankyrin domain family, member F | 0.0397958 |
| MATR3 | matrin 3 | 0.0397452 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0391606 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0386142 |
| ECT2 | epithelial cell transforming 2 | 0.0383298 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0381988 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0381199 |
| TENM3 | teneurin transmembrane protein 3 | 0.0380831 |
| TRIM37 | tripartite motif containing 37 | 0.0374399 |
| KIF5B | kinesin family member 5B | 0.0363249 |
| RPL37 | ribosomal protein L37 | 0.0363106 |
| USP34 | ubiquitin specific peptidase 34 | 0.0360565 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0360353 |
| NHSL1 | NHS-like 1 | 0.0356629 |
| ASPH | aspartate beta-hydroxylase | 0.0356075 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0343594 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0343269 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.034217 |
| MEMO1 | mediator of cell motility 1 | 0.0342139 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0340778 |
| CLDND1 | claudin domain containing 1 | 0.0339938 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0336471 |
| CDK17 | cyclin-dependent kinase 17 | 0.0334591 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0328838 |
| SYT1 | synaptotagmin I | 0.0325882 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0323367 |
| RPL19 | ribosomal protein L19 | 0.0317261 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0314989 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0313668 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0313046 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0312934 |
| QKI | QKI, KH domain containing, RNA binding | 0.031172 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0311434 |
| RYK | receptor-like tyrosine kinase | 0.0310441 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0310076 |
| RTN4 | reticulon 4 | 0.030937 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0307814 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0306612 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0301979 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0301388 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0300986 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0298038 |
| RPLP2 | ribosomal protein, large, P2 | 0.0297975 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0297844 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.029756 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0297375 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0296982 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0292759 |
| RPS4X | ribosomal protein S4, X-linked | 0.0291535 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290592 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0289891 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0286664 |
| TNPO1 | transportin 1 | 0.02863 |
| CEP192 | centrosomal protein 192kDa | 0.0285108 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0282021 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0280166 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0279888 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.027952 |
| LMO7 | LIM domain 7 | 0.0279153 |
| RPL7A | ribosomal protein L7a | 0.027874 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.126437 |
| PCDH7 | protocadherin 7 | -0.0882534 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0702524 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0677314 |
| PTMA | prothymosin, alpha | -0.06581 |
| EDARADD | EDAR-associated death domain | -0.0570007 |
| EHBP1 | EH domain binding protein 1 | -0.0564948 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0553429 |
| VIM | vimentin | -0.0496144 |
| DST | dystonin | -0.0478208 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0440808 |
| HMGA1 | high mobility group AT-hook 1 | -0.0424641 |
| MMP12 | matrix metallopeptidase 12 | -0.0423784 |
| H1-0 | H1.0 linker histone | -0.0412501 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0411263 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0405267 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0391497 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0369862 |
| CENPF | centromere protein F, 350/400kDa | -0.0359436 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.034892 |
| RASAL2 | RAS protein activator like 2 | -0.0340293 |
| NEBL | nebulette | -0.0339784 |
| YBX3 | Y box binding protein 3 | -0.0321623 |
| CMIP | c-Maf inducing protein | -0.0314901 |
| CCND1 | cyclin D1 | -0.0312754 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.031176 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0306838 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0306151 |
| ZNF804A | zinc finger protein 804A | -0.0300857 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0297169 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0282583 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0281666 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0274925 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274823 |
| SUMF1 | sulfatase modifying factor 1 | -0.0269516 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0253835 |
| RPS27A | ribosomal protein S27a | -0.0243796 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0243083 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0242631 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0242543 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0242026 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0235357 |
| PFN1 | profilin 1 | -0.0234947 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0234625 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0232008 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0230509 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0229775 |
| PHF14 | PHD finger protein 14 | -0.0225012 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0223423 |
| TPM4 | tropomyosin 4 | -0.0218865 |
| PARD3 | par-3 family cell polarity regulator | -0.0218214 |
| RPS6 | ribosomal protein S6 | -0.0215967 |
| HMGA2 | high mobility group AT-hook 2 | -0.0214038 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.021221 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0210683 |
| GOLGA4 | golgin A4 | -0.0203597 |
| MPG | N-methylpurine-DNA glycosylase | -0.0202869 |
| ENOSF1 | enolase superfamily member 1 | -0.0199173 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0193449 |
| ETV6 | ets variant 6 | -0.0191551 |
| VCAN | versican | -0.0182289 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0180858 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0177249 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.0177144 |
| ATP11A | ATPase, class VI, type 11A | -0.0177005 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.017697 |
| ATAD5 | ATPase family, AAA domain containing 5 | -0.0176361 |
| MECOM | MDS1 and EVI1 complex locus | -0.0175504 |
| HMGB1 | high mobility group box 1 | -0.0173569 |
| TP53 | tumor protein p53 | -0.0171709 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0171506 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0169284 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0168661 |
| CUX1 | cut-like homeobox 1 | -0.0168206 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0167397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.016735 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0166153 |
| ZNF281 | zinc finger protein 281 | -0.0166069 |
| USP40 | ubiquitin specific peptidase 40 | -0.0165937 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0165918 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0165809 |
| RPL26 | ribosomal protein L26 | -0.0165798 |
| WWOX | WW domain containing oxidoreductase | -0.0164055 |
| ATG10 | autophagy related 10 | -0.0163767 |
| FOXN3 | forkhead box N3 | -0.0162658 |
| GANAB | glucosidase, alpha; neutral AB | -0.0162013 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0161787 |
| CANX | calnexin | -0.0160357 |
| ANK2 | ankyrin 2, neuronal | -0.015974 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0159703 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.015911 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0158666 |
| DIAPH3 | diaphanous-related formin 3 | -0.015852 |
| PRR11 | proline rich 11 | -0.0157571 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0157543 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0157301 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0157128 |
| RNF216 | ring finger protein 216 | -0.0157058 |
| CDC42 | cell division cycle 42 | -0.0157007 |
| CUL4B | cullin 4B | -0.0156966 |
