| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Menadione_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.136592 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.133195 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.129176 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.107479 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0881159 |
| PTMA | prothymosin, alpha | 0.0805102 |
| POTEF | POTE ankyrin domain family, member F | 0.0674635 |
| TMSB4X | thymosin beta 4, X-linked | 0.0639169 |
| CANX | calnexin | 0.0562493 |
| DST | dystonin | 0.0535661 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0499405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0489242 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0487657 |
| AHNAK | AHNAK nucleoprotein | 0.0473743 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0471116 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0440461 |
| SPAG9 | sperm associated antigen 9 | 0.04385 |
| PLK2 | polo-like kinase 2 | 0.0436434 |
| SET | SET nuclear proto-oncogene | 0.0434278 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0433719 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0427221 |
| APP | amyloid beta (A4) precursor protein | 0.0421444 |
| CENPF | centromere protein F, 350/400kDa | 0.0409209 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0396816 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0389676 |
| ZNF292 | zinc finger protein 292 | 0.0336365 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0334753 |
| FNIP1 | folliculin interacting protein 1 | 0.0319348 |
| RBM39 | RNA binding motif protein 39 | 0.0319274 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.031783 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.031695 |
| MATR3 | matrin 3 | 0.0316674 |
| TOP1 | topoisomerase (DNA) I | 0.0313527 |
| NUP58 | nucleoporin 58 | 0.0312794 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0312462 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.030814 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0307849 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0307317 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0306618 |
| ANLN | anillin, actin binding protein | 0.0306326 |
| RAI1 | retinoic acid induced 1 | 0.030277 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0297332 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0294569 |
| XPO1 | exportin 1 | 0.0290107 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0289706 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0289325 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0286047 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0282634 |
| PGK1 | phosphoglycerate kinase 1 | 0.0282048 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.027854 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276066 |
| OGA | O-GlcNAcase | 0.0272836 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271219 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0270304 |
| FMNL2 | formin-like 2 | 0.0269711 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.026737 |
| IPO7 | importin 7 | 0.0267313 |
| CALR | calreticulin | 0.0266594 |
| SERINC1 | serine incorporator 1 | 0.0261027 |
| LDHA | lactate dehydrogenase A | 0.0260772 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0258365 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.025675 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0254848 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0254641 |
| WDR43 | WD repeat domain 43 | 0.0248425 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0247043 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0246795 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0245276 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0242391 |
| TNPO1 | transportin 1 | 0.0241524 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.023958 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0234773 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0234626 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0232842 |
| QKI | QKI, KH domain containing, RNA binding | 0.0232195 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0232067 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0230446 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0229741 |
| RNF145 | ring finger protein 145 | 0.0229657 |
| ZNF217 | zinc finger protein 217 | 0.0227277 |
| STAG2 | stromal antigen 2 | 0.0227079 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0226311 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0225994 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0224671 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0224628 |
| MKI67 | marker of proliferation Ki-67 | 0.0220766 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0220667 |
| YBX1 | Y box binding protein 1 | 0.0220287 |
| SUCO | SUN domain containing ossification factor | 0.0219919 |
| PTK2 | protein tyrosine kinase 2 | 0.0218858 |
| EFNA5 | ephrin-A5 | 0.0218442 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0216873 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215663 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0214955 |
| HMGB2 | high mobility group box 2 | 0.0214112 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0213827 |
| TMEM123 | transmembrane protein 123 | 0.0213663 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0212433 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0210393 |
| NCKAP1 | NCK-associated protein 1 | 0.02096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.272158 |
| MT2A | metallothionein 2A | -0.223237 |
| VIM | vimentin | -0.145989 |
| TMSB10 | thymosin beta 10 | -0.069132 |
| MT1X | metallothionein 1X | -0.0583954 |
| MT1E | metallothionein 1E | -0.0577565 |
| TP63 | tumor protein p63 | -0.0563618 |
| FTL | ferritin, light polypeptide | -0.0557044 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.054432 |
| HLA-B | major histocompatibility complex, class I, B | -0.0509796 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0442591 |
| HMGA1 | high mobility group AT-hook 1 | -0.044194 |
| EGR1 | early growth response 1 | -0.0415918 |
| RPS19 | ribosomal protein S19 | -0.0397249 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0391844 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0355599 |
| RPL35A | ribosomal protein L35a | -0.0345283 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0328771 |
| ACTG1 | actin gamma 1 | -0.0323357 |
| RPLP2 | ribosomal protein, large, P2 | -0.0313855 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0307811 |
| ANGPTL4 | angiopoietin-like 4 | -0.0290382 |
| RPL28 | ribosomal protein L28 | -0.0275176 |
| RPS8 | ribosomal protein S8 | -0.0274141 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0260629 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0259653 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0243133 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0241956 |
| RPS23 | ribosomal protein S23 | -0.0240699 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233939 |
| SRGN | serglycin | -0.0231999 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0230113 |
| RPL36 | ribosomal protein L36 | -0.0224918 |
| AREG | amphiregulin | -0.0223343 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216026 |
| S100A10 | S100 calcium binding protein A10 | -0.0215416 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0214604 |
| RPS29 | ribosomal protein S29 | -0.0213022 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0209022 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0207719 |
| FOSL1 | FOS-like antigen 1 | -0.0205761 |
| TXNRD1 | thioredoxin reductase 1 | -0.0202535 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0200973 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0199154 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0195515 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0195361 |
| RPS10 | ribosomal protein S10 | -0.0195163 |
| RPS13 | ribosomal protein S13 | -0.0188991 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.018894 |
| RPL27 | ribosomal protein L27 | -0.0185437 |
| RPS21 | ribosomal protein S21 | -0.0181254 |
| PRDX1 | peroxiredoxin 1 | -0.0178118 |
| RPL36A | ribosomal protein L36a | -0.0176786 |
| S100A6 | S100 calcium binding protein A6 | -0.0175449 |
| EMP1 | epithelial membrane protein 1 | -0.017401 |
| PXDN | peroxidasin | -0.0171978 |
| HLA-A | major histocompatibility complex, class I, A | -0.0170691 |
| CDCP1 | CUB domain containing protein 1 | -0.0166874 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0166366 |
| RPL38 | ribosomal protein L38 | -0.0165902 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0164762 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0164732 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0162364 |
| TGM2 | transglutaminase 2 | -0.0162092 |
| RPS15 | ribosomal protein S15 | -0.0161893 |
| RPL8 | ribosomal protein L8 | -0.0158705 |
| ECE1 | endothelin converting enzyme 1 | -0.0158661 |
| TAPBP | TAP binding protein (tapasin) | -0.0156455 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0155392 |
| S100A11 | S100 calcium binding protein A11 | -0.0152944 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0152428 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0152338 |
| S100A9 | S100 calcium binding protein A9 | -0.0150903 |
| RPS11 | ribosomal protein S11 | -0.014871 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0147838 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0146284 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0145765 |
| UPP1 | uridine phosphorylase 1 | -0.0145564 |
| RPL34 | ribosomal protein L34 | -0.0145337 |
| PDE10A | phosphodiesterase 10A | -0.013998 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0138992 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0135739 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0133907 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0133609 |
| CMIP | c-Maf inducing protein | -0.0132917 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0130398 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.013014 |
| RPS14 | ribosomal protein S14 | -0.0129272 |
| HMOX1 | heme oxygenase 1 | -0.0125962 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0125148 |
| RPS27 | ribosomal protein S27 | -0.0124659 |
| TRIM56 | tripartite motif containing 56 | -0.0123441 |
| RPL37A | ribosomal protein L37a | -0.0122633 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0122598 |
| RPL35 | ribosomal protein L35 | -0.0122528 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0121227 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0121197 |
| RPL7A | ribosomal protein L7a | -0.0119073 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0117661 |
| RPS16 | ribosomal protein S16 | -0.011708 |
