| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.156139 |
| ASPH | aspartate beta-hydroxylase | 0.0833401 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.074295 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0709546 |
| TOP1 | topoisomerase (DNA) I | 0.0629654 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0600095 |
| RNF145 | ring finger protein 145 | 0.056588 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0559694 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0499758 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0495714 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0483594 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0477565 |
| NCKAP1 | NCK-associated protein 1 | 0.0470776 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0438388 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0428882 |
| NUP58 | nucleoporin 58 | 0.0418683 |
| MED13L | mediator complex subunit 13-like | 0.0413708 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0394198 |
| ATP13A3 | ATPase type 13A3 | 0.0382804 |
| LAMC2 | laminin, gamma 2 | 0.0372315 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.035554 |
| TFG | TRK-fused gene | 0.0350483 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.034991 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0346944 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.034562 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0338709 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0333032 |
| SLMAP | sarcolemma associated protein | 0.0328482 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0325839 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0324278 |
| CES1 | carboxylesterase 1 | 0.0309474 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0308823 |
| SMAD3 | SMAD family member 3 | 0.030575 |
| RAB10 | RAB10, member RAS oncogene family | 0.0304742 |
| MSN | moesin | 0.0304054 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0303449 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0302974 |
| RCOR1 | REST corepressor 1 | 0.030281 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0301758 |
| PTK2 | protein tyrosine kinase 2 | 0.0299601 |
| UVRAG | UV radiation resistance associated | 0.0288408 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0286453 |
| LMO7 | LIM domain 7 | 0.0285807 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0284707 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0284228 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0270741 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0270427 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0264844 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0263079 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0260699 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0260454 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256824 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0255257 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254081 |
| PTEN | phosphatase and tensin homolog | 0.0250538 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.024826 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0248146 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0246085 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0237443 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0234778 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0232876 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0232199 |
| CCNL1 | cyclin L1 | 0.0230878 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0228966 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0227132 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0222132 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0221335 |
| CUL3 | cullin 3 | 0.0221045 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0220463 |
| PCBP2 | poly(rC) binding protein 2 | 0.0220427 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0219213 |
| MYOF | myoferlin | 0.0218987 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0218972 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0217747 |
| HYOU1 | hypoxia up-regulated 1 | 0.0216423 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0214409 |
| MYO5B | myosin VB | 0.020905 |
| TJP1 | tight junction protein 1 | 0.0207918 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0206777 |
| TBK1 | TANK-binding kinase 1 | 0.020432 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.020275 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0193833 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0193631 |
| ANXA5 | annexin A5 | 0.019184 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0191343 |
| SETD5 | SET domain containing 5 | 0.0190616 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0189839 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0188946 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0188666 |
| POTEF | POTE ankyrin domain family, member F | 0.018769 |
| ARRDC3 | arrestin domain containing 3 | 0.0182011 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0181691 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.018132 |
| USP3 | ubiquitin specific peptidase 3 | 0.0181043 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0180739 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0180179 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0179746 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0177534 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0175369 |
| RASA2 | RAS p21 protein activator 2 | 0.0175173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.425354 |
| TMSB10 | thymosin beta 10 | -0.154801 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.143707 |
| MT2A | metallothionein 2A | -0.127067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0952226 |
| PTMA | prothymosin, alpha | -0.090867 |
| RPLP1 | ribosomal protein, large, P1 | -0.0771159 |
| RPL35A | ribosomal protein L35a | -0.0720525 |
| RPS3 | ribosomal protein S3 | -0.068358 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0661762 |
| NDRG1 | N-myc downstream regulated 1 | -0.0648241 |
| RPS8 | ribosomal protein S8 | -0.0587078 |
| H1-0 | H1.0 linker histone | -0.0571098 |
| RPL34 | ribosomal protein L34 | -0.0550517 |
| SEC61G | Sec61 gamma subunit | -0.0510695 |
| RPS24 | ribosomal protein S24 | -0.0500732 |
| HDLBP | high density lipoprotein binding protein | -0.0497097 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0481668 |
| FTL | ferritin, light polypeptide | -0.0461344 |
| RPS25 | ribosomal protein S25 | -0.0458988 |
| S100A10 | S100 calcium binding protein A10 | -0.045453 |
| STC1 | stanniocalcin 1 | -0.0453921 |
| ANXA2 | annexin A2 | -0.0450626 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0449766 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0442658 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0437614 |
| CANX | calnexin | -0.0437541 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0434463 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0427772 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.041935 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.041805 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.040978 |
| RPL37A | ribosomal protein L37a | -0.039967 |
| ACTG1 | actin gamma 1 | -0.0398004 |
| RPLP0 | ribosomal protein, large, P0 | -0.0394534 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0391499 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0383278 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0382692 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0374968 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.037034 |
| EMP1 | epithelial membrane protein 1 | -0.0366 |
| RPS27A | ribosomal protein S27a | -0.0365198 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0356554 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.035556 |
| LAMB3 | laminin, beta 3 | -0.035469 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0347891 |
| ENO1 | enolase 1, (alpha) | -0.0345648 |
| HLA-B | major histocompatibility complex, class I, B | -0.0343215 |
| RPS29 | ribosomal protein S29 | -0.0341869 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0338251 |
| EGR1 | early growth response 1 | -0.0332498 |
| GOLGB1 | golgin B1 | -0.032859 |
| RACK1 | receptor for activated C kinase 1 | -0.0328278 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.03261 |
| GM2A | GM2 ganglioside activator | -0.0324898 |
| UBC | ubiquitin C | -0.0324584 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0324489 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322845 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0322552 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0322133 |
| RPL31 | ribosomal protein L31 | -0.0322112 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0321893 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0316353 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0313395 |
| RPL19 | ribosomal protein L19 | -0.0311897 |
| RPL8 | ribosomal protein L8 | -0.0311585 |
| ABLIM1 | actin binding LIM protein 1 | -0.0310255 |
| MT1X | metallothionein 1X | -0.0305162 |
| RPL12 | ribosomal protein L12 | -0.0303133 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299117 |
| GNAS | GNAS complex locus | -0.0297355 |
| B2M | beta-2-microglobulin | -0.0296438 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0293968 |
| RPL11 | ribosomal protein L11 | -0.0293011 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0291981 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0290643 |
| MORF4L2 | mortality factor 4 like 2 | -0.0290489 |
| INTS6 | integrator complex subunit 6 | -0.0285099 |
| RPS19 | ribosomal protein S19 | -0.0276804 |
| ARF1 | ADP-ribosylation factor 1 | -0.0276346 |
| S100P | S100 calcium binding protein P | -0.0274358 |
| IER3 | immediate early response 3 | -0.0271424 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0270643 |
| RPL7 | ribosomal protein L7 | -0.0270472 |
| CCNI | cyclin I | -0.027029 |
| RPL30 | ribosomal protein L30 | -0.0269853 |
| RPS21 | ribosomal protein S21 | -0.0269453 |
| LAMA4 | laminin, alpha 4 | -0.0268808 |
| RPS23 | ribosomal protein S23 | -0.0267011 |
| HBP1 | HMG-box transcription factor 1 | -0.026217 |
| MKI67 | marker of proliferation Ki-67 | -0.0262075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258419 |
| AHNAK | AHNAK nucleoprotein | -0.0257887 |
| CSTB | cystatin B (stefin B) | -0.0257802 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0256276 |
| FAM13A | family with sequence similarity 13, member A | -0.0253327 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0250825 |
| RPL23 | ribosomal protein L23 | -0.0246915 |
| RPL37 | ribosomal protein L37 | -0.0244837 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0241765 |
