| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.140778 |
| MYOF | myoferlin | 0.106375 |
| TXNRD1 | thioredoxin reductase 1 | 0.105456 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0991267 |
| ASPH | aspartate beta-hydroxylase | 0.0924959 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0880822 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0730433 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0729775 |
| NRCAM | neuronal cell adhesion molecule | 0.0666352 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0659757 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0653213 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0644757 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0606664 |
| EFNA5 | ephrin-A5 | 0.0577151 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0560511 |
| KYNU | kynureninase | 0.0559119 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.055223 |
| CD109 | CD109 molecule | 0.0539378 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0460464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0417011 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0384737 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0379254 |
| STC2 | stanniocalcin 2 | 0.0371889 |
| NEK7 | NIMA-related kinase 7 | 0.0364177 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0352048 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0340627 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0326817 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0317527 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0308679 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.030065 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0296106 |
| ATXN1 | ataxin 1 | 0.0289075 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0285024 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0284865 |
| VMP1 | vacuole membrane protein 1 | 0.0280287 |
| PTEN | phosphatase and tensin homolog | 0.02793 |
| CTSC | cathepsin C | 0.0274664 |
| TNPO1 | transportin 1 | 0.0268183 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0267059 |
| FMNL2 | formin-like 2 | 0.0256837 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250456 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0248497 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0246561 |
| NRG1 | neuregulin 1 | 0.0244591 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0240896 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0237833 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0233197 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0229375 |
| MB21D2 | Mab-21 domain containing 2 | 0.0227557 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0223753 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0223569 |
| NHSL1 | NHS-like 1 | 0.021857 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0216852 |
| PCBP3 | poly(rC) binding protein 3 | 0.0216192 |
| ANO6 | anoctamin 6 | 0.0213317 |
| RTN4 | reticulon 4 | 0.0210344 |
| MEF2A | myocyte enhancer factor 2A | 0.0210029 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0207799 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0204603 |
| TUSC3 | tumor suppressor candidate 3 | 0.0199956 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196456 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.019515 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0193267 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0191684 |
| ENAH | enabled homolog (Drosophila) | 0.0190394 |
| AUTS2 | autism susceptibility candidate 2 | 0.0187963 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0186559 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0183891 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0181458 |
| EPGN | epithelial mitogen | 0.0180865 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0180367 |
| DST | dystonin | 0.0179829 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0178442 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0176609 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0175723 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0173105 |
| TENM3 | teneurin transmembrane protein 3 | 0.0170794 |
| AHR | aryl hydrocarbon receptor | 0.0170767 |
| NTN4 | netrin 4 | 0.0170707 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0170384 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0168773 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0167971 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0167434 |
| MSN | moesin | 0.0167314 |
| KIF16B | kinesin family member 16B | 0.0162915 |
| SNX9 | sorting nexin 9 | 0.0160486 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0159412 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 | 0.0155903 |
| NCKAP1 | NCK-associated protein 1 | 0.0155608 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0154165 |
| VCL | vinculin | 0.0154027 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0152348 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0152028 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0149793 |
| SEPTIN10 | septin 10 | 0.0149648 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0149322 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0148525 |
| CDH13 | cadherin 13 | 0.0147589 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0147405 |
| USP34 | ubiquitin specific peptidase 34 | 0.0145387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.163447 |
| TMSB10 | thymosin beta 10 | -0.162156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139541 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.123535 |
| PTMA | prothymosin, alpha | -0.122051 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.108237 |
| RPS6 | ribosomal protein S6 | -0.106828 |
| VIM | vimentin | -0.104755 |
| FN1 | fibronectin 1 | -0.0919084 |
| RPLP1 | ribosomal protein, large, P1 | -0.0887078 |
| RPS12 | ribosomal protein S12 | -0.0799868 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0788515 |
| RPL26 | ribosomal protein L26 | -0.0778342 |
| FTL | ferritin, light polypeptide | -0.0743553 |
| RPL37A | ribosomal protein L37a | -0.0742737 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0709475 |
| PDE10A | phosphodiesterase 10A | -0.0694531 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0658106 |
| RPS19 | ribosomal protein S19 | -0.0651326 |
| RPL12 | ribosomal protein L12 | -0.0630686 |
| RPL23 | ribosomal protein L23 | -0.0607886 |
| RPS8 | ribosomal protein S8 | -0.0604684 |
| RPS3 | ribosomal protein S3 | -0.059946 |
| S100A6 | S100 calcium binding protein A6 | -0.0577629 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0574899 |
| RPL35A | ribosomal protein L35a | -0.0565473 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0555199 |
| MT2A | metallothionein 2A | -0.0542011 |
| RPL31 | ribosomal protein L31 | -0.0541568 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0525076 |
| B2M | beta-2-microglobulin | -0.049732 |
| RPL19 | ribosomal protein L19 | -0.0489799 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0463035 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0453008 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0452116 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0449914 |
| RPL9 | ribosomal protein L9 | -0.0447058 |
| RPL36 | ribosomal protein L36 | -0.0436869 |
| RPS27 | ribosomal protein S27 | -0.0418967 |
| RGS2 | regulator of G-protein signaling 2 | -0.0412885 |
| RACK1 | receptor for activated C kinase 1 | -0.0385409 |
| GNAS | GNAS complex locus | -0.0378622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0374675 |
| RPL13A | ribosomal protein L13a | -0.036639 |
| RPS27A | ribosomal protein S27a | -0.036107 |
| RPL34 | ribosomal protein L34 | -0.0360939 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.035224 |
| RPLP0 | ribosomal protein, large, P0 | -0.034798 |
| RPS29 | ribosomal protein S29 | -0.0345631 |
| RPL11 | ribosomal protein L11 | -0.0341991 |
| RPS4X | ribosomal protein S4, X-linked | -0.0341549 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0338755 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0337162 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0334957 |
| RPS14 | ribosomal protein S14 | -0.0330105 |
| RPL35 | ribosomal protein L35 | -0.0321644 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0320901 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.031851 |
| RPL37 | ribosomal protein L37 | -0.031812 |
| YBX3 | Y box binding protein 3 | -0.031642 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0315076 |
| TBXT | T-box transcription factor T | -0.0313454 |
| GRAMD1B | GRAM domain containing 1B | -0.0312898 |
| RPS24 | ribosomal protein S24 | -0.0311344 |
| KIAA0825 | KIAA0825 | -0.0309922 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.03038 |
| RPS23 | ribosomal protein S23 | -0.0300883 |
| RPLP2 | ribosomal protein, large, P2 | -0.0297237 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0294652 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0291533 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0291371 |
| SRGN | serglycin | -0.0290314 |
| CANX | calnexin | -0.0289256 |
| RPL7A | ribosomal protein L7a | -0.0287302 |
| RPS17 | ribosomal protein S17 | -0.0283681 |
| RPL18 | ribosomal protein L18 | -0.0283041 |
| RPS2 | ribosomal protein S2 | -0.0273559 |
| RPL36A | ribosomal protein L36a | -0.0271425 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0269888 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.026948 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0268258 |
| HLA-A | major histocompatibility complex, class I, A | -0.0264753 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0263586 |
| ACTG1 | actin gamma 1 | -0.026075 |
| RPS16 | ribosomal protein S16 | -0.0258431 |
| RPL32 | ribosomal protein L32 | -0.0256147 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0252726 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0251611 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0250771 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0250045 |
| RPL5 | ribosomal protein L5 | -0.0248678 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0248631 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0247265 |
| HLA-B | major histocompatibility complex, class I, B | -0.0246308 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0246243 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0244292 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0241099 |
| RPL7 | ribosomal protein L7 | -0.0240273 |
| TPI1 | triosephosphate isomerase 1 | -0.0239885 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0239881 |
