| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0412899 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0311379 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0276369 |
| ANLN | anillin, actin binding protein | 0.0219599 |
| ECT2 | epithelial cell transforming 2 | 0.0209206 |
| QKI | QKI, KH domain containing, RNA binding | 0.0204021 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0196327 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0192132 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0192064 |
| USP3 | ubiquitin specific peptidase 3 | 0.0189281 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0188201 |
| USP12 | ubiquitin specific peptidase 12 | 0.0185742 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0177624 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0167856 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0159461 |
| MTF2 | metal response element binding transcription factor 2 | 0.0153985 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.015327 |
| CFL2 | cofilin 2 (muscle) | 0.0152129 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0151505 |
| LDHD | lactate dehydrogenase D | 0.0151063 |
| USP28 | ubiquitin specific peptidase 28 | 0.0149049 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0145718 |
| ANXA5 | annexin A5 | 0.0145357 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0143671 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0143072 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0142547 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.0141136 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0138964 |
| RPL3 | ribosomal protein L3 | 0.0134753 |
| NCKAP1 | NCK-associated protein 1 | 0.0134382 |
| MTMR3 | myotubularin related protein 3 | 0.0134295 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0132732 |
| PDS5B | PDS5 cohesin associated factor B | 0.0132279 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.013185 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0130547 |
| HSF2 | heat shock transcription factor 2 | 0.0129096 |
| MITF | microphthalmia-associated transcription factor | 0.0129043 |
| TWF1 | twinfilin actin binding protein 1 | 0.0128752 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0128244 |
| KNTC1 | kinetochore associated 1 | 0.0128077 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0126639 |
| NLGN1 | neuroligin 1 | 0.0125335 |
| POTEF | POTE ankyrin domain family, member F | 0.0123294 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0123277 |
| KIF13A | kinesin family member 13A | 0.0122485 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 0.0121969 |
| ATG5 | autophagy related 5 | 0.0120799 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0120462 |
| H1-5 | H1.5 linker histone, cluster member | 0.01201 |
| RBL1 | retinoblastoma-like 1 | 0.0119445 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0118419 |
| PBK | PDZ binding kinase | 0.0116829 |
| RANBP9 | RAN binding protein 9 | 0.0116821 |
| CERT1 | ceramide transporter 1 | 0.0116798 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0116461 |
| UBQLN1 | ubiquilin 1 | 0.011627 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.011496 |
| SGO2 | shugoshin 2 | 0.0114704 |
| RIOK3 | RIO kinase 3 | 0.0114698 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 0.0114419 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.0114419 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0113762 |
| FAT1 | FAT atypical cadherin 1 | 0.0113729 |
| NUP58 | nucleoporin 58 | 0.0113201 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0112541 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0112536 |
| PTEN | phosphatase and tensin homolog | 0.0112386 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0112335 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0111831 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0111342 |
| DMXL1 | Dmx-like 1 | 0.0111271 |
| NBAS | neuroblastoma amplified sequence | 0.0111207 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0110569 |
| DSEL | dermatan sulfate epimerase-like | 0.0110536 |
| STK26 | serine/threonine protein kinase 26 | 0.0109644 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.0109504 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0109355 |
| CENPC | centromere protein C | 0.0109199 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0109156 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0109016 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0108995 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0108794 |
| NUP153 | nucleoporin 153kDa | 0.0108551 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.0107454 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.0107355 |
| WDR43 | WD repeat domain 43 | 0.0106878 |
| RBBP7 | retinoblastoma binding protein 7 | 0.0106767 |
| AAK1 | AP2 associated kinase 1 | 0.0106213 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.0106069 |
| CEP70 | centrosomal protein 70kDa | 0.0105448 |
| RPP30 | ribonuclease P/MRP 30kDa subunit | 0.0105111 |
| LSM12 | LSM12 homolog (S. cerevisiae) | 0.0105097 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0103689 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0103665 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0103114 |
| MTO1 | mitochondrial tRNA translation optimization 1 | 0.0103059 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0103017 |
| NEK2 | NIMA-related kinase 2 | 0.0102766 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0102565 |
| SELENOI | selenoprotein I | 0.0102333 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.301545 |
| TMSB10 | thymosin beta 10 | -0.187617 |
| COL11A1 | collagen, type XI, alpha 1 | -0.18433 |
| PTMA | prothymosin, alpha | -0.166149 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.126534 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124779 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.115821 |
| CADM2 | cell adhesion molecule 2 | -0.0970441 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.092501 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0910321 |
| RPS16 | ribosomal protein S16 | -0.0901724 |
| PCDH9 | protocadherin 9 | -0.086592 |
| COL3A1 | collagen, type III, alpha 1 | -0.0841939 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0806755 |
| GPC3 | glypican 3 | -0.0787057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.077341 |
| COL1A2 | collagen, type I, alpha 2 | -0.0773184 |
| ITGAV | integrin, alpha V | -0.0761125 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0755682 |
| RPS8 | ribosomal protein S8 | -0.0736244 |
| RPS27A | ribosomal protein S27a | -0.0734633 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0728429 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0693589 |
| ACTG1 | actin gamma 1 | -0.0671365 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.06489 |
| RPLP1 | ribosomal protein, large, P1 | -0.0611883 |
| RPS6 | ribosomal protein S6 | -0.0607994 |
| RPL23 | ribosomal protein L23 | -0.0583262 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0574049 |
| ENO1 | enolase 1, (alpha) | -0.057043 |
| CALR | calreticulin | -0.0567267 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0565797 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0557848 |
| UBC | ubiquitin C | -0.0555702 |
| RPL5 | ribosomal protein L5 | -0.0530025 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0522349 |
| RPL35A | ribosomal protein L35a | -0.0519256 |
| PEG10 | paternally expressed 10 | -0.05166 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0493788 |
| B2M | beta-2-microglobulin | -0.0487904 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0481726 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0479716 |
| RPS12 | ribosomal protein S12 | -0.0479553 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0477948 |
| RPL26 | ribosomal protein L26 | -0.0475021 |
| PARD3B | par-3 family cell polarity regulator beta | -0.046403 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.046399 |
| S100A10 | S100 calcium binding protein A10 | -0.0461245 |
| RPL37A | ribosomal protein L37a | -0.0449963 |
| PHIP | pleckstrin homology domain interacting protein | -0.0445331 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0443137 |
| RPS19 | ribosomal protein S19 | -0.0437687 |
| TENM3 | teneurin transmembrane protein 3 | -0.0412271 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0407575 |
| RPS3 | ribosomal protein S3 | -0.0400334 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0395107 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0389642 |
| LRRC4C | leucine rich repeat containing 4C | -0.0386635 |
| RPL19 | ribosomal protein L19 | -0.0386162 |
| GNAS | GNAS complex locus | -0.0379047 |
| THBS1 | thrombospondin 1 | -0.0378568 |
| RPS13 | ribosomal protein S13 | -0.0370299 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0368783 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0363913 |
| RPL31 | ribosomal protein L31 | -0.0362944 |
| RPL12 | ribosomal protein L12 | -0.0362566 |
| EMP1 | epithelial membrane protein 1 | -0.0361932 |
| RPL37 | ribosomal protein L37 | -0.0361387 |
| RPLP2 | ribosomal protein, large, P2 | -0.0360566 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0359726 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0357213 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0356898 |
| PGK1 | phosphoglycerate kinase 1 | -0.0356682 |
| RPL36A | ribosomal protein L36a | -0.0346199 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0345299 |
| LDHA | lactate dehydrogenase A | -0.034528 |
| AHNAK | AHNAK nucleoprotein | -0.03369 |
| RPL11 | ribosomal protein L11 | -0.0335472 |
| SET | SET nuclear proto-oncogene | -0.0335426 |
| HMGB2 | high mobility group box 2 | -0.0335143 |
| PFN1 | profilin 1 | -0.0332693 |
| COL5A2 | collagen, type V, alpha 2 | -0.033001 |
| CDH19 | cadherin 19, type 2 | -0.0329285 |
| YBX1 | Y box binding protein 1 | -0.0321908 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0319484 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0311737 |
| RPS21 | ribosomal protein S21 | -0.0310713 |
| HMGB1 | high mobility group box 1 | -0.0305143 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0303702 |
| TMSB4X | thymosin beta 4, X-linked | -0.0299969 |
| RACK1 | receptor for activated C kinase 1 | -0.0298051 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0298026 |
| CALU | calumenin | -0.0297002 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0293967 |
| RAD51B | RAD51 paralog B | -0.0293322 |
| RPL32 | ribosomal protein L32 | -0.0293081 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0292539 |
| RPS25 | ribosomal protein S25 | -0.0291814 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0291497 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0291294 |
