| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0914185 |
| POTEF | POTE ankyrin domain family, member F | 0.0858394 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0809125 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0695168 |
| SPAG9 | sperm associated antigen 9 | 0.0667181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0666335 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.065918 |
| NAV2 | neuron navigator 2 | 0.0615213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0609899 |
| TXNRD1 | thioredoxin reductase 1 | 0.0604745 |
| CCNB1 | cyclin B1 | 0.0573777 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0561051 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0528618 |
| TPX2 | TPX2, microtubule-associated | 0.0527234 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.049268 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0475368 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0469241 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0466752 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0464612 |
| TFG | TRK-fused gene | 0.0459352 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0457641 |
| SET | SET nuclear proto-oncogene | 0.0452893 |
| SQSTM1 | sequestosome 1 | 0.0452115 |
| CENPF | centromere protein F, 350/400kDa | 0.0446792 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0444316 |
| CEP170 | centrosomal protein 170kDa | 0.0437666 |
| PKM | pyruvate kinase, muscle | 0.0434936 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0426025 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0409507 |
| RBM25 | RNA binding motif protein 25 | 0.0407197 |
| MSN | moesin | 0.0400827 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0390308 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0381605 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0371818 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0370908 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0361919 |
| SYNJ2 | synaptojanin 2 | 0.0361298 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0361039 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0356662 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0356029 |
| SETD5 | SET domain containing 5 | 0.0352637 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.03465 |
| CALU | calumenin | 0.0346169 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0343825 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0343743 |
| MKI67 | marker of proliferation Ki-67 | 0.0341797 |
| NUP58 | nucleoporin 58 | 0.0337215 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0337114 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0333874 |
| MIS18BP1 | MIS18 binding protein 1 | 0.033239 |
| CD44 | CD44 molecule (Indian blood group) | 0.0329984 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0328483 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0322343 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321641 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0320804 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0314818 |
| KMT5B | lysine methyltransferase 5B | 0.0312962 |
| HBS1L | HBS1-like translational GTPase | 0.031238 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0310764 |
| HPCAL1 | hippocalcin-like 1 | 0.0310151 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0309616 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0309412 |
| MMP1 | matrix metallopeptidase 1 | 0.0304777 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0303419 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.030297 |
| KIF5B | kinesin family member 5B | 0.0302754 |
| DNER | delta/notch-like EGF repeat containing | 0.0302311 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300304 |
| FAM168A | family with sequence similarity 168, member A | 0.0299243 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0298551 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0298464 |
| GOLM2 | golgi membrane protein 2 | 0.0296948 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0296861 |
| MEF2A | myocyte enhancer factor 2A | 0.0296444 |
| SLMAP | sarcolemma associated protein | 0.029625 |
| LMO7 | LIM domain 7 | 0.0293361 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0289756 |
| CDK17 | cyclin-dependent kinase 17 | 0.0288971 |
| HJURP | Holliday junction recognition protein | 0.0287983 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0285514 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0284841 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0280797 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0280639 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0279985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0279567 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0279002 |
| MAP1B | microtubule-associated protein 1B | 0.027836 |
| MORF4L1 | mortality factor 4 like 1 | 0.0277071 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.027591 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0274957 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0273966 |
| CCNK | cyclin K | 0.027192 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0271883 |
| BBX | bobby sox homolog (Drosophila) | 0.0270327 |
| RPL3 | ribosomal protein L3 | 0.0270313 |
| PTMS | parathymosin | 0.0268746 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0265612 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0264715 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0264219 |
| ITGA6 | integrin, alpha 6 | 0.0263272 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.0971071 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0919117 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0751247 |
| YBX3 | Y box binding protein 3 | -0.0678198 |
| LDHA | lactate dehydrogenase A | -0.067334 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0573759 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0522327 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0509162 |
| TMSB10 | thymosin beta 10 | -0.0507021 |
| JMJD1C | jumonji domain containing 1C | -0.0505427 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0505425 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0502342 |
| EGR1 | early growth response 1 | -0.0476788 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0460643 |
| OSMR | oncostatin M receptor | -0.0459236 |
| GNAS | GNAS complex locus | -0.0455682 |
| RPL35A | ribosomal protein L35a | -0.0443769 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0436521 |
| NDRG1 | N-myc downstream regulated 1 | -0.0421303 |
| RPLP1 | ribosomal protein, large, P1 | -0.0408471 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.040591 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0403394 |
| CENPP | centromere protein P | -0.0396424 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.039415 |
| HDAC9 | histone deacetylase 9 | -0.0393029 |
| HDLBP | high density lipoprotein binding protein | -0.0392091 |
| ZNF609 | zinc finger protein 609 | -0.0389214 |
| KIAA1328 | KIAA1328 | -0.0385973 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0385871 |
| RPL12 | ribosomal protein L12 | -0.0371008 |
| TCF12 | transcription factor 12 | -0.0369539 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0368835 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0368777 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0367442 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0366737 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0365381 |
| BRD4 | bromodomain containing 4 | -0.0360371 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0355351 |
| RPS12 | ribosomal protein S12 | -0.0355204 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0354986 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0351527 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0349783 |
| TP53 | tumor protein p53 | -0.0349529 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0338143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0338073 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0331379 |
| ACER3 | alkaline ceramidase 3 | -0.0322339 |
| SLC38A2 | solute carrier family 38, member 2 | -0.032201 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0321607 |
| RAD51B | RAD51 paralog B | -0.0320717 |
| RPL26 | ribosomal protein L26 | -0.031725 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.031699 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0315765 |
| CFDP1 | craniofacial development protein 1 | -0.03155 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0314913 |
| GPC6 | glypican 6 | -0.0314856 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0312488 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0311145 |
| CERT1 | ceramide transporter 1 | -0.0305564 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | -0.0303196 |
| TMEM245 | transmembrane protein 245 | -0.0302034 |
| ZNF91 | zinc finger protein 91 | -0.0300528 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0299472 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0295755 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0295559 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0293012 |
| AATF | apoptosis antagonizing transcription factor | -0.0292241 |
| FCHO2 | FCH domain only 2 | -0.0291358 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.029133 |
| PHF14 | PHD finger protein 14 | -0.0289854 |
| ETF1 | eukaryotic translation termination factor 1 | -0.0285282 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0285155 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0283238 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0279969 |
| HLA-C | major histocompatibility complex, class I, C | -0.0279286 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0279135 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0278556 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.02755 |
| RPL27A | ribosomal protein L27a | -0.0274965 |
| KIF13A | kinesin family member 13A | -0.0274942 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0272396 |
| RPL7A | ribosomal protein L7a | -0.0269654 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0269286 |
| CREBBP | CREB binding protein | -0.0267774 |
| RPL30 | ribosomal protein L30 | -0.0267074 |
| FMN1 | formin 1 | -0.0266755 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0263386 |
| ANO6 | anoctamin 6 | -0.0263269 |
| CCDC91 | coiled-coil domain containing 91 | -0.0263032 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0261946 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0258964 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.025628 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0255654 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.0255374 |
| PDE8A | phosphodiesterase 8A | -0.0254035 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0252337 |
| TMEM14B | transmembrane protein 14B | -0.0251189 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0250055 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.024927 |
| FANCI | Fanconi anemia, complementation group I | -0.0248034 |
