| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Menadione perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Menadione_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.233898 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.144576 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.140542 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.138918 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.137499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.113052 |
| STC2 | stanniocalcin 2 | 0.108658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.104677 |
| CD109 | CD109 molecule | 0.0982811 |
| NRG1 | neuregulin 1 | 0.0938088 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.091578 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0835852 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.072485 |
| CADM1 | cell adhesion molecule 1 | 0.0665092 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0641886 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0637223 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0627425 |
| POTEF | POTE ankyrin domain family, member F | 0.0627213 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0586821 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0582684 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0536191 |
| FBN1 | fibrillin 1 | 0.0526488 |
| EREG | epiregulin | 0.0526374 |
| TXNRD1 | thioredoxin reductase 1 | 0.0519284 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0511608 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0477506 |
| FAM13A | family with sequence similarity 13, member A | 0.0454931 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0431583 |
| PLIN2 | perilipin 2 | 0.0425255 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0425131 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0417752 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0412486 |
| RUNX2 | runt-related transcription factor 2 | 0.0407496 |
| TPM3 | tropomyosin 3 | 0.0402096 |
| MYOF | myoferlin | 0.0391231 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0382955 |
| PTK2 | protein tyrosine kinase 2 | 0.0380032 |
| ENO1 | enolase 1, (alpha) | 0.0376212 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0375192 |
| VEGFA | vascular endothelial growth factor A | 0.0374451 |
| B2M | beta-2-microglobulin | 0.0373746 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0365758 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0363249 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0359641 |
| PKM | pyruvate kinase, muscle | 0.0350251 |
| ZNF292 | zinc finger protein 292 | 0.0349808 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0348917 |
| GOLGA4 | golgin A4 | 0.0337839 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.033094 |
| FAT1 | FAT atypical cadherin 1 | 0.0330338 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0325558 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0324323 |
| SUCO | SUN domain containing ossification factor | 0.032239 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0319352 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0317028 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0316691 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0316057 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0307168 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0303222 |
| FLNB | filamin B, beta | 0.0299034 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0293407 |
| MEF2A | myocyte enhancer factor 2A | 0.0280974 |
| TRAM1 | translocation associated membrane protein 1 | 0.0274932 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0274461 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0274372 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0273042 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0271066 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267953 |
| TXNIP | thioredoxin interacting protein | 0.0266822 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0260426 |
| HDGF | hepatoma-derived growth factor | 0.0259109 |
| ANXA5 | annexin A5 | 0.025817 |
| ZNF638 | zinc finger protein 638 | 0.0256515 |
| LYST | lysosomal trafficking regulator | 0.0256136 |
| RNF145 | ring finger protein 145 | 0.0254766 |
| INSIG2 | insulin induced gene 2 | 0.0254248 |
| DENND5B | DENN/MADD domain containing 5B | 0.0254235 |
| NDRG1 | N-myc downstream regulated 1 | 0.0253718 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0253341 |
| SECISBP2L | SECIS binding protein 2-like | 0.025265 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0250135 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0247169 |
| ARRDC3 | arrestin domain containing 3 | 0.0245487 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0244362 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.023993 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0239574 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0237774 |
| CCNL1 | cyclin L1 | 0.023716 |
| CENPF | centromere protein F, 350/400kDa | 0.0236889 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0236623 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0232925 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0231374 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.023122 |
| TMF1 | TATA element modulatory factor 1 | 0.0230254 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0230071 |
| ATL2 | atlastin GTPase 2 | 0.0227996 |
| RIOK3 | RIO kinase 3 | 0.022493 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0222673 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0220838 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.022032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.398247 |
| FN1 | fibronectin 1 | -0.168217 |
| EXT1 | exostosin glycosyltransferase 1 | -0.105094 |
| VCL | vinculin | -0.0991399 |
| NTN4 | netrin 4 | -0.0797578 |
| OSMR | oncostatin M receptor | -0.0702377 |
| TMSB10 | thymosin beta 10 | -0.0681584 |
| MT2A | metallothionein 2A | -0.06685 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0599124 |
| HLA-B | major histocompatibility complex, class I, B | -0.057535 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0556959 |
| GLIS3 | GLIS family zinc finger 3 | -0.0541655 |
| RAB31 | RAB31, member RAS oncogene family | -0.0504172 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0449797 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0449348 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0405519 |
| TOP1 | topoisomerase (DNA) I | -0.0402288 |
| PALLD | palladin, cytoskeletal associated protein | -0.0395037 |
| KSR1 | kinase suppressor of ras 1 | -0.0393613 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0377699 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0373667 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0366769 |
| ACTN4 | actinin, alpha 4 | -0.0365481 |
| NRP1 | neuropilin 1 | -0.0364851 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.035198 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0345561 |
| CD44 | CD44 molecule (Indian blood group) | -0.0334272 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0332721 |
| FOXP1 | forkhead box P1 | -0.0332591 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0330333 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0322694 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0322223 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0321032 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.031288 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0305626 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0304869 |
| SEPTIN9 | septin 9 | -0.0299192 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.029741 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284395 |
| FHL2 | four and a half LIM domains 2 | -0.0284135 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0282119 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0276732 |
| RPL35A | ribosomal protein L35a | -0.0274552 |
| ASPH | aspartate beta-hydroxylase | -0.0273747 |
| ETV1 | ets variant 1 | -0.0269178 |
| MYO10 | myosin X | -0.0262615 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262594 |
| RIGI | RNA sensor RIG-I | -0.0258765 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0256709 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0253694 |
| EGR1 | early growth response 1 | -0.0253177 |
| TNNC1 | troponin C type 1 (slow) | -0.0245758 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0245065 |
| GLCCI1 | glucocorticoid induced 1 | -0.0243116 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0241967 |
| RPS19 | ribosomal protein S19 | -0.0240518 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0240296 |
| FTL | ferritin, light polypeptide | -0.0240049 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0238403 |
| AOPEP | aminopeptidase O (putative) | -0.0233496 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0231347 |
| PELO | pelota homolog (Drosophila) | -0.0230753 |
| RRBP1 | ribosome binding protein 1 | -0.0227747 |
| YBX3 | Y box binding protein 3 | -0.0227382 |
| SDC2 | syndecan 2 | -0.0226177 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0226041 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0225388 |
| PTMA | prothymosin, alpha | -0.022446 |
| SMOX | spermine oxidase | -0.0222818 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0221705 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0219108 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0218301 |
| SYT1 | synaptotagmin I | -0.0212127 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0209504 |
| NXN | nucleoredoxin | -0.0208384 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0205683 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0204907 |
| RPS21 | ribosomal protein S21 | -0.0203888 |
| TGFB2 | transforming growth factor, beta 2 | -0.0202409 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0201129 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0199185 |
| ARF1 | ADP-ribosylation factor 1 | -0.0197008 |
| RAB10 | RAB10, member RAS oncogene family | -0.0195791 |
| RNF213 | ring finger protein 213 | -0.0194623 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0194028 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.019283 |
| NAV1 | neuron navigator 1 | -0.0191419 |
| MX2 | MX dynamin-like GTPase 2 | -0.0189283 |
| IER3 | immediate early response 3 | -0.0187198 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0186129 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0184631 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.018334 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0182864 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0182364 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0179184 |
| ITGB5 | integrin, beta 5 | -0.0178926 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0177689 |
| TMEM263 | transmembrane protein 263 | -0.0177099 |
| KLF10 | Kruppel-like factor 10 | -0.0177061 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0176375 |
