Meningitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Meningitis is a nervous system infectious disease characterized as an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells. Meningitis is a diffuse infection caused by a variety of different agents. (Human Disease Ontology, DOID_9471)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008581
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Genes

41 genes/proteins associated with the disease Meningitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
C8A complement component 8, alpha polypeptide 2.88009
C8B complement component 8, beta polypeptide 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
IL10 interleukin 10 1.63899
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.60221
TNF tumor necrosis factor 1.55304
IL6 interleukin 6 1.39952
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.3716
IL1B interleukin 1, beta 1.34227
MMP3 matrix metallopeptidase 3 1.30208
POMC proopiomelanocortin 1.28333
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.26052
VEGFA vascular endothelial growth factor A 1.25338
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.2437
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.22979
IFNG interferon, gamma 1.2137
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.20784
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.19835
CCL3 chemokine (C-C motif) ligand 3 1.19179
MMP13 matrix metallopeptidase 13 1.18456
CCL2 chemokine (C-C motif) ligand 2 1.18391
TGFB1 transforming growth factor, beta 1 1.17134
JUN jun proto-oncogene 1.14064
CAT catalase 1.12151
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.12151
BAX BCL2-associated X protein 1.11151
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.10769
VCAM1 vascular cell adhesion molecule 1 1.10282
ICAM1 intercellular adhesion molecule 1 1.09786
IGFBP5 insulin-like growth factor binding protein 5 1.09611
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.09471
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.08055
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.07269
CXCL8 chemokine (C-X-C motif) ligand 8 1.06734
CCNG1 cyclin G1 1.06225
COL3A1 collagen, type III, alpha 1 1.04721
NPY neuropeptide Y 1.04574
IL4 interleukin 4 1.03419
F3 coagulation factor III (thromboplastin, tissue factor) 1.03159
RGS4 regulator of G-protein signaling 4 1.02634
INS insulin 1.02225