Meningitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Meningitis is a nervous system infectious disease characterized as an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells. Meningitis is a diffuse infection caused by a variety of different agents. (Human Disease Ontology, DOID_9471)
External Link https://www.disgenet.org/browser/0/1/0/C0497299
Similar Terms
Downloads & Tools

Genes

277 genes associated with the disease Meningitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AADAT aminoadipate aminotransferase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ADAM17 ADAM metallopeptidase domain 17
AGRP agouti related neuropeptide
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APRT adenine phosphoribosyltransferase
AQP4 aquaporin 4
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARTN artemin
ATN1 atrophin 1
AZU1 azurocidin 1
BATF basic leucine zipper transcription factor, ATF-like
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BLNK B-cell linker
BPI bactericidal/permeability-increasing protein
BTK Bruton agammaglobulinemia tyrosine kinase
C17ORF62 chromosome 17 open reading frame 62
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4BPA complement component 4 binding protein, alpha
C5 complement component 5
C5AR1 complement component 5a receptor 1
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C9 complement component 9
CADM1 cell adhesion molecule 1
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CARD14 caspase recruitment domain family, member 14
CARD9 caspase recruitment domain family, member 9
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC33 coiled-coil domain containing 33
CCL3 chemokine (C-C motif) ligand 3
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CD19 CD19 molecule
CD248 CD248 molecule, endosialin
CD274 CD274 molecule
CD276 CD276 molecule
CD47 CD47 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CFH complement factor H
CFP complement factor properdin
CGA glycoprotein hormones, alpha polypeptide
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNTNAP1 contactin associated protein 1
COL11A1 collagen, type XI, alpha 1
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPB2 carboxypeptidase B2 (plasma)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCTN4 dynactin 4 (p62)
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DNASE1L3 deoxyribonuclease I-like 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENOSF1 enolase superfamily member 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EXOC6B exocyst complex component 6B
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FN1 fibronectin 1
FOXP3 forkhead box P3
FST follistatin
GALNS galactosamine (N-acetyl)-6-sulfatase
GAST gastrin
GC group-specific component (vitamin D binding protein)
GDNF glial cell derived neurotrophic factor
GORASP1 golgi reassembly stacking protein 1, 65kDa
GRAP2 GRB2-related adaptor protein 2
GYPC glycophorin C (Gerbich blood group)
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGH immunoglobulin heavy locus
IGLL1 immunoglobulin lambda-like polypeptide 1
IL10 interleukin 10
IL12A interleukin 12A
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL4 interleukin 4
IL6 interleukin 6
IRAK4 interleukin-1 receptor-associated kinase 4
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK3 Janus kinase 3
KLK3 kallikrein-related peptidase 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KYNU kynureninase
LAMC2 laminin, gamma 2
LAMP3 lysosomal-associated membrane protein 3
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LRG1 leucine-rich alpha-2-glycoprotein 1
LRRC8A leucine rich repeat containing 8 family, member A
LSAMP limbic system-associated membrane protein
LYZ lysozyme
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPT microtubule-associated protein tau
MARCH9 membrane-associated ring finger (C3HC4) 9
MARCO macrophage receptor with collagenous structure
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MDK midkine (neurite growth-promoting factor 2)
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MFAP1 microfibrillar-associated protein 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSC musculin
MYD88 myeloid differentiation primary response 88
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOA6 nuclear receptor coactivator 6
NDE1 nudE neurodevelopment protein 1
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NGF nerve growth factor (beta polypeptide)
NLRC4 NLR family, CARD domain containing 4
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NTF3 neurotrophin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGG1 8-oxoguanine DNA glycosylase
OMP olfactory marker protein
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP1 poly (ADP-ribose) polymerase 1
PDE7A phosphodiesterase 7A
PECAM1 platelet/endothelial cell adhesion molecule 1
PER2 period circadian clock 2
PIGR polymeric immunoglobulin receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PMP2 peripheral myelin protein 2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRDX2 peroxiredoxin 2
PRF1 perforin 1 (pore forming protein)
PRMT1 protein arginine methyltransferase 1
PRNP prion protein
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PYCARD PYD and CARD domain containing
RAET1E retinoic acid early transcript 1E
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RECQL4 RecQ protein-like 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOF ras homolog family member F (in filopodia)
RIPK2 receptor-interacting serine-threonine kinase 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAMM50 SAMM50 sorting and assembly machinery component
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SH2D1A SH2 domain containing 1A
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
STAG2 stromal antigen 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STK32C serine/threonine kinase 32C
STS steroid sulfatase (microsomal), isozyme S
SUMF2 sulfatase modifying factor 2
SYT1 synaptotagmin I
TBC1D22A TBC1 domain family, member 22A
TBK1 TANK-binding kinase 1
TCF12 transcription factor 12
TCF3 transcription factor 3
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THPO thrombopoietin
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
UBAC1 UBA domain containing 1
UBAC2 UBA domain containing 2
UROD uroporphyrinogen decarboxylase
VANGL1 VANGL planar cell polarity protein 1
VIM vimentin
WAS Wiskott-Aldrich syndrome
WDHD1 WD repeat and HMG-box DNA binding protein 1
WIPF1 WAS/WASL interacting protein family, member 1
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1