Menopause Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. (Experimental Factor Ontology, EFO_0003922)
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Genes

31 genes associated with the trait Menopause in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
MCM8 minichromosome maintenance complex component 8 2.06459
TMEM150B transmembrane protein 150B 1.99044
UIMC1 ubiquitin interaction motif containing 1 1.70488
HELQ helicase, POLQ-like 1.37626
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.37626
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 1.27842
PRRC2A proline-rich coiled-coil 2A 1.26538
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.1806
TLK1 tousled-like kinase 1 1.16559
POLG polymerase (DNA directed), gamma 1.09623
FNDC4 fibronectin type III domain containing 4 1.0562
SYCP2L synaptonemal complex protein 2-like 1.02102
BRSK1 BR serine/threonine kinase 1 0.960111
TDRD3 tudor domain containing 3 0.944178
SLC35F3 solute carrier family 35, member F3 0.87362
EXO1 exonuclease 1 0.870981
NLRP11 NLR family, pyrin domain containing 11 0.866561
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1 0.70194
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.654022
SARDH sarcosine dehydrogenase 0.619418
BANP BTG3 associated nuclear protein 0.609816
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.60625
AGBL1 ATP/GTP binding protein-like 1 0.592255
ADGRA2 adhesion G protein-coupled receptor A2 0.585749
SLC44A4 solute carrier family 44, member 4 0.552134
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.443956
LRRN4 leucine rich repeat neuronal 4 0.443956
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.406869
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.33862
RNF44 ring finger protein 44 0.33862
THSD4 thrombospondin, type I, domain containing 4 0.100542