Merkel Cell Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0007129
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Genes

215 genes associated with the disease Merkel Cell Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ADAM10 ADAM metallopeptidase domain 10
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15 arachidonate 15-lipoxygenase
APC adenomatous polyposis coli
ARHGAP24 Rho GTPase activating protein 24
ASCL1 achaete-scute family bHLH transcription factor 1
ASXL1 additional sex combs like transcriptional regulator 1
ATN1 atrophin 1
ATOH1 atonal homolog 1 (Drosophila)
AXIN1 axin 1
AXIN2 axin 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD4 bromodomain containing 4
C17ORF97 chromosome 17 open reading frame 97
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC54 coiled-coil domain containing 54
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL17 chemokine (C-C motif) ligand 17
CCND1 cyclin D1
CCR4 chemokine (C-C motif) receptor 4
CD151 CD151 molecule (Raph blood group)
CD163 CD163 molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD274 CD274 molecule
CD276 CD276 molecule
CD68 CD68 molecule
CD9 CD9 molecule
CD99 CD99 molecule
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CHGA chromogranin A
CKAP4 cytoskeleton-associated protein 4
CLIC1 chloride intracellular channel 1
CLIC4 chloride intracellular channel 4
CLTA clathrin, light chain A
COL11A2 collagen, type XI, alpha 2
COMMD3-BMI1 COMMD3-BMI1 readthrough
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DNER delta/notch-like EGF repeat containing
DUSP2 dual specificity phosphatase 2
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
EP400 E1A binding protein p400
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ETFA electron-transfer-flavoprotein, alpha polypeptide
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FOPNL FGFR1OP N-terminal like
FOXP3 forkhead box P3
FZD4 frizzled class receptor 4
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GNLY granulysin
GPC3 glypican 3
GPR132 G protein-coupled receptor 132
GPR151 G protein-coupled receptor 151
GPR4 G protein-coupled receptor 4
GPR65 G protein-coupled receptor 65
GPRC6A G protein-coupled receptor, class C, group 6, member A
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL4 interleukin 4
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INSM1 insulinoma-associated 1
JAG1 jagged 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT8 keratin 8, type II
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LDHB lactate dehydrogenase B
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LMLN leishmanolysin-like (metallopeptidase M8 family)
LPAR3 lysophosphatidic acid receptor 3
MAP2K7 mitogen-activated protein kinase kinase 7
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP26 matrix metallopeptidase 26
MMP28 matrix metallopeptidase 28
MRGPRX1 MAS-related GPR, member X1
MRGPRX3 MAS-related GPR, member X3
MRGPRX4 MAS-related GPR, member X4
MRTFA myocardin related transcription factor A
MRTFB myocardin related transcription factor B
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCAM1 neural cell adhesion molecule 1
NDRG1 N-myc downstream regulated 1
NEUROD1 neuronal differentiation 1
NGF nerve growth factor (beta polypeptide)
NKX2-1 NK2 homeobox 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OXER1 oxoeicosanoid (OXE) receptor 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PDCD1 programmed cell death 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POSTN periostin, osteoblast specific factor
POU3F2 POU class 3 homeobox 2
POU4F3 POU class 4 homeobox 3
PRDX2 peroxiredoxin 2
PRUNE2 prune homolog 2 (Drosophila)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPA protein phosphatase 2 phosphatase activator
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRG protein tyrosine phosphatase, receptor type, G
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
REST RE1-silencing transcription factor
RPE65 retinal pigment epithelium-specific protein 65kDa
RPP14 ribonuclease P/MRP 14kDa subunit
S100A9 S100 calcium binding protein A9
SARDH sarcosine dehydrogenase
SATB2 SATB homeobox 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SDS serine dehydratase
SELE selectin E
SELENBP1 selenium binding protein 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B6 splicing factor 3b, subunit 6, 14kDa
SGSM3 small G protein signaling modulator 3
SH3GLB1 SH3-domain GRB2-like endophilin B1
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLN sarcolipin
SMAD4 SMAD family member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI2 snail family zinc finger 2
SORD sorbitol dehydrogenase
SOX2 SRY (sex determining region Y)-box 2
SPA17 sperm autoantigenic protein 17
SPHK1 sphingosine kinase 1
SPPL2A signal peptide peptidase like 2A
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
SUB1 SUB1 homolog (S. cerevisiae)
SYP synaptophysin
TDO2 tryptophan 2,3-dioxygenase
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS13 transmembrane protease, serine 13
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TTF1 transcription termination factor, RNA polymerase I
TWIST1 twist family bHLH transcription factor 1
TYR tyrosinase
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VIM vimentin
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB24 zinc finger and BTB domain containing 24