Metabolism of amino acids and derivatives Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-71291
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Genes

352 proteins participating in the Metabolism of amino acids and derivatives pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AADAT aminoadipate aminotransferase
AANAT aralkylamine N-acetyltransferase
AASS aminoadipate-semialdehyde synthase
ACAD8 acyl-CoA dehydrogenase family, member 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACAT1 acetyl-CoA acetyltransferase 1
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ADI1 acireductone dioxygenase 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRM1 adhesion regulating molecule 1
AFMID arylformamidase
AGMAT agmatine ureohydrolase (agmatinase)
AGXT alanine-glyoxylate aminotransferase
AGXT2 alanine--glyoxylate aminotransferase 2
AHCY adenosylhomocysteinase
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
AMD1 adenosylmethionine decarboxylase 1
AMDHD1 amidohydrolase domain containing 1
AMT aminomethyltransferase
APIP APAF1 interacting protein
ARG1 arginase 1
ARG2 arginase 2
ASL argininosuccinate lyase
ASMT acetylserotonin O-methyltransferase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPA aspartoacylase
ASPG asparaginase
ASPNAT aspartate N-acetyltransferase
ASRGL1 asparaginase like 1
ASS1 argininosuccinate synthase 1
AUH AU RNA binding protein/enoyl-CoA hydratase
AZIN1 antizyme inhibitor 1
AZIN2 antizyme inhibitor 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCKDK branched chain ketoacid dehydrogenase kinase
BHMT betaine--homocysteine S-methyltransferase
BHMT2 betaine--homocysteine S-methyltransferase 2
CARNMT1 carnosine N-methyltransferase 1
CARNS1 carnosine synthase 1
CBS cystathionine-beta-synthase
CDO1 cysteine dioxygenase type 1
CGA glycoprotein hormones, alpha polypeptide
CHDH choline dehydrogenase
CKB creatine kinase, brain
CKM creatine kinase, muscle
CKMT1A creatine kinase, mitochondrial 1A
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRYM crystallin, mu
CSAD cysteine sulfinic acid decarboxylase
CTH cystathionine gamma-lyase
DAO D-amino-acid oxidase
DARS1 aspartyl-tRNA synthetase 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DBT dihydrolipoamide branched chain transacylase E2
DCT dopachrome tautomerase
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDO D-aspartate oxidase
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIO1 deiodinase, iodothyronine, type I
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMGDH dimethylglycine dehydrogenase
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific
ENOPH1 enolase-phosphatase 1
EPRS1 glutamyl-prolyl-tRNA synthetase 1
ETHE1 ethylmalonic encephalopathy 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FMO1 flavin containing monooxygenase 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FTCD formimidoyltransferase cyclodeaminase
GADL1 glutamate decarboxylase-like 1
GAMT guanidinoacetate N-methyltransferase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCAT glycine C-acetyltransferase
GCDH glutaryl-CoA dehydrogenase
GCSH glycine cleavage system protein H (aminomethyl carrier)
GLDC glycine dehydrogenase (decarboxylating)
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GLUL glutamate-ammonia ligase
GNMT glycine N-methyltransferase
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSR glutathione reductase
GSTZ1 glutathione S-transferase zeta 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAL histidine ammonia-lyase
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HDC histidine decarboxylase
HGD homogentisate 1,2-dioxygenase
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HNMT histamine N-methyltransferase
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HPD 4-hydroxyphenylpyruvate dioxygenase
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HYKK hydroxylysine kinase
IARS1 isoleucyl-tRNA synthetase 1
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IL4I1 interleukin 4 induced 1
INMT indolethylamine N-methyltransferase
IVD isovaleryl-CoA dehydrogenase
IYD iodotyrosine deiodinase
KARS1 lysyl-tRNA synthetase 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KYAT1 kynurenine aminotransferase 1
KYAT3 kynurenine aminotransferase 3
KYNU kynureninase
LARS1 leucyl-tRNA synthetase 1
MARS1 methionyl-tRNA synthetase 1
MAT1A methionine adenosyltransferase I, alpha
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MPST mercaptopyruvate sulfurtransferase
MRI1 methylthioribose-1-phosphate isomerase 1
MRPS36 mitochondrial ribosomal protein S36
MTAP methylthioadenosine phosphorylase
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAGS N-acetylglutamate synthase
NMRAL1 NmrA-like family domain containing 1
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
OAT ornithine aminotransferase
OAZ1 ornithine decarboxylase antizyme 1
OAZ2 ornithine decarboxylase antizyme 2
OAZ3 ornithine decarboxylase antizyme 3
OCA2 oculocutaneous albinism II
ODC1 ornithine decarboxylase 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OTC ornithine carbamoyltransferase
PAH phenylalanine hydroxylase
PAOX polyamine oxidase (exo-N4-amino)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PHGDH phosphoglycerate dehydrogenase
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PIPOX pipecolic acid oxidase
PNMT phenylethanolamine N-methyltransferase
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PRODH proline dehydrogenase (oxidase) 1
PRODH2 proline dehydrogenase (oxidase) 2
PSAT1 phosphoserine aminotransferase 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSPH phosphoserine phosphatase
PSTK phosphoseryl-tRNA kinase
PXMP2 peroxisomal membrane protein 2, 22kDa
PYCR1 pyrroline-5-carboxylate reductase 1
PYCR2 pyrroline-5-carboxylate reductase family, member 2
PYCR3 pyrroline-5-carboxylate reductase 3
QARS1 glutaminyl-tRNA synthetase 1
QDPR quinoid dihydropteridine reductase
RARS1 arginyl-tRNA synthetase 1
RIDA reactive intermediate imine deaminase A homolog
RIMKLA ribosomal modification protein rimK-like family member A
RIMKLB ribosomal modification protein rimK-like family member B
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL10L ribosomal protein L10-like
RPL11 ribosomal protein L11
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL13A ribosomal protein L13a
RPL14 ribosomal protein L14
RPL15 ribosomal protein L15
RPL17 ribosomal protein L17
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL19 ribosomal protein L19
RPL21 ribosomal protein L21
RPL22 ribosomal protein L22
RPL22L1 ribosomal protein L22-like 1
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL26L1 ribosomal protein L26-like 1
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL28 ribosomal protein L28
RPL29 ribosomal protein L29
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL34 ribosomal protein L34
RPL35 ribosomal protein L35
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL36A ribosomal protein L36a
RPL36AL ribosomal protein L36a-like
RPL37 ribosomal protein L37
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPL39 ribosomal protein L39
RPL39L ribosomal protein L39-like
RPL3L ribosomal protein L3-like
RPL4 ribosomal protein L4
RPL41 ribosomal protein L41
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPL9 ribosomal protein L9
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15 ribosomal protein S15
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS21 ribosomal protein S21
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27 ribosomal protein S27
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RPSA ribosomal protein SA
SARDH sarcosine dehydrogenase
SARS1 seryl-tRNA synthetase 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCLY selenocysteine lyase
SDS serine dehydratase
SDSL serine dehydratase-like
SECISBP2 SECIS binding protein 2
SEM1 SEM1 26S proteasome subunit
SEPHS2 selenophosphate synthetase 2
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
SERINC1 serine incorporator 1
SERINC2 serine incorporator 2
SERINC3 serine incorporator 3
SERINC4 serine incorporator 4
SERINC5 serine incorporator 5
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A44 solute carrier family 25, member 44
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC45A2 solute carrier family 45, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMOX spermine oxidase
SMS spermine synthase
SQOR sulfide quinone oxidoreductase
SRM spermidine synthase
SRR serine racemase
SUOX sulfite oxidase
TAT tyrosine aminotransferase
TDO2 tryptophan 2,3-dioxygenase
TH tyrosine hydroxylase
TMLHE trimethyllysine hydroxylase, epsilon
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TPO thyroid peroxidase
TSHB thyroid stimulating hormone, beta
TST thiosulfate sulfurtransferase (rhodanese)
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TXN2 thioredoxin 2
TXNRD1 thioredoxin reductase 1
TYR tyrosinase
TYRP1 tyrosinase-related protein 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UROC1 urocanate hydratase 1