Metastatic Castration-Resistant Prostate Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4721208
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Genes

126 genes associated with the disease Metastatic Castration-Resistant Prostate Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACP3 acid phosphatase 3
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALPP alkaline phosphatase, placental
AR androgen receptor
ARSG arylsulfatase G
ASRGL1 asparaginase like 1
ATM ATM serine/threonine kinase
ATRNL1 attractin-like 1
BAAT bile acid CoA:amino acid N-acyltransferase
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BID BH3 interacting domain death agonist
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
CCL27 chemokine (C-C motif) ligand 27
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CD274 CD274 molecule
CD46 CD46 molecule, complement regulatory protein
CDC20 cell division cycle 20
CDK12 cyclin-dependent kinase 12
CHGA chromogranin A
CIP2A cellular inhibitor of PP2A
CKS1B CDC28 protein kinase regulatory subunit 1B
CLU clusterin
COL11A2 collagen, type XI, alpha 2
COX5A cytochrome c oxidase subunit Va
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPOX coproporphyrinogen oxidase
CRTC1 CREB regulated transcription coactivator 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DNER delta/notch-like EGF repeat containing
ENDOD1 endonuclease domain containing 1
ENO2 enolase 2 (gamma, neuronal)
EPCAM epithelial cell adhesion molecule
EPHB2 EPH receptor B2
ERCC1 excision repair cross-complementation group 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETFA electron-transfer-flavoprotein, alpha polypeptide
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FASN fatty acid synthase
FERMT2 fermitin family member 2
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GDF15 growth differentiation factor 15
GLI1 GLI family zinc finger 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRPR gastrin-releasing peptide receptor
HAVCR2 hepatitis A virus cellular receptor 2
HDAC3 histone deacetylase 3
HDAC9 histone deacetylase 9
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
HOXB13 homeobox B13
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IL6 interleukin 6
IMPACT impact RWD domain protein
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNIP3 Kv channel interacting protein 3, calsenilin
KLK3 kallikrein-related peptidase 3
LDHA lactate dehydrogenase A
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
LMNA lamin A/C
MAPK1 mitogen-activated protein kinase 1
MED12 mediator complex subunit 12
MED12L mediator complex subunit 12-like
MIP major intrinsic protein of lens fiber
MMRN1 multimerin 1
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT10 N-acetyltransferase 10 (GCN5-related)
NCAPH non-SMC condensin I complex, subunit H
NKX3-1 NK3 homeobox 1
NPEPPS aminopeptidase puromycin sensitive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRP1 neuropilin 1
ONECUT2 one cut homeobox 2
PARP1 poly (ADP-ribose) polymerase 1
PDLIM3 PDZ and LIM domain 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIMREG PICALM interacting mitotic regulator
PLAG1 pleiomorphic adenoma gene 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POSTN periostin, osteoblast specific factor
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PTEN phosphatase and tensin homolog
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
REST RE1-silencing transcription factor
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RUNX2 runt-related transcription factor 2
SEPTIN1 septin 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC44A4 solute carrier family 44, member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD4 SMAD family member 4
SOX5 SRY (sex determining region Y)-box 5
SPP1 secreted phosphoprotein 1
SPRTN SprT-like N-terminal domain
SST somatostatin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TET2 tet methylcytosine dioxygenase 2
TLE5 TLE family member 5, transcriptional modulator
TMPRSS2 transmembrane protease, serine 2
TP53 tumor protein p53
TRIM24 tripartite motif containing 24
TUBB3 tubulin, beta 3 class III
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFP36 ZFP36 ring finger protein