Metastatic Intraocular Melanoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4725091
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Genes

52 genes associated with the disease Metastatic Intraocular Melanoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCR7 chemokine (C-C motif) receptor 7
CD163 CD163 molecule
CD274 CD274 molecule
COL11A2 collagen, type XI, alpha 2
CREB1 cAMP responsive element binding protein 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR4 chemokine (C-X-C motif) receptor 4
EPHB2 EPH receptor B2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HDAC9 histone deacetylase 9
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MBD4 methyl-CpG binding domain protein 4
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
PARP1 poly (ADP-ribose) polymerase 1
PDCD1 programmed cell death 1
PHPT1 phosphohistidine phosphatase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PRAME preferentially expressed antigen in melanoma
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRRT2 proline-rich transmembrane protein 2
S100A2 S100 calcium binding protein A2
SETD2 SET domain containing 2
SF3B1 splicing factor 3b, subunit 1, 155kDa
SOX3 SRY (sex determining region Y)-box 3
SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1
SPANXA2 SPANX family, member A2
SPANXC SPANX family, member C
SPANXD SPANX family, member D
SPP1 secreted phosphoprotein 1
TYR tyrosinase
VIM vimentin
WEE1 WEE1 G2 checkpoint kinase