Metastatic Renal Cell Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0278678
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Genes

138 genes associated with the disease Metastatic Renal Cell Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACLY ATP citrate lyase
ACVRL1 activin A receptor type II-like 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ANXA1 annexin A1
ANXA6 annexin A6
APOB apolipoprotein B
APRT adenine phosphoribosyltransferase
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
AZIN2 antizyme inhibitor 2
C5AR1 complement component 5a receptor 1
CA9 carbonic anhydrase IX
CCL21 chemokine (C-C motif) ligand 21
CCR7 chemokine (C-C motif) receptor 7
CD274 CD274 molecule
CD80 CD80 molecule
COL18A1 collagen, type XVIII, alpha 1
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2IP DAB2 interacting protein
DCTN6 dynactin 6
DLC1 DLC1 Rho GTPase activating protein
DLEC1 deleted in lung and esophageal cancer 1
DYNLL1 dynein, light chain, LC8-type 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EOMES eomesodermin
EPHA2 EPH receptor A2
EPHB2 EPH receptor B2
FBXO11 F-box protein 11
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXP3 forkhead box P3
GADL1 glutamate decarboxylase-like 1
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GJB1 gap junction protein, beta 1, 32kDa
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HILPDA hypoxia inducible lipid droplet-associated
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFI27 interferon, alpha-inducible protein 27
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IL13 interleukin 13
IL15 interleukin 15
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
ISG20 interferon stimulated exonuclease gene 20kDa
JAG1 jagged 1
KDR kinase insert domain receptor
KRT20 keratin 20, type I
MAPK1 mitogen-activated protein kinase 1
MET MET proto-oncogene, receptor tyrosine kinase
MFAP1 microfibrillar-associated protein 1
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NRP2 neuropilin 2
NTN1 netrin 1
NUCLEOLIN nucleolin multifunctional protein
PAX8 paired box 8
PBRM1 polybromo 1
PDCD1 programmed cell death 1
PDGFD platelet derived growth factor D
PEG3 paternally expressed 3
PELI1 pellino E3 ubiquitin protein ligase 1
PER2 period circadian clock 2
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PITX1 paired-like homeodomain 1
PKLR pyruvate kinase, liver and RBC
PRDM6 PR domain containing 6
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RBM45 RNA binding motif protein 45
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATA2 spermatogenesis associated 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFE3 transcription factor binding to IGHM enhancer 3
TICAM2 toll-like receptor adaptor molecule 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TP53 tumor protein p53
TSC2 tuberous sclerosis 2
TTR transthyretin
TYMS thymidylate synthetase
UBASH3B ubiquitin associated and SH3 domain containing B
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
ULK1 unc-51 like autophagy activating kinase 1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VNN2 vanin 2