Methadone Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4. (Chemical Entities of Biological Interest Ontology, CHEBI_6807)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008691
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Genes

28 genes/proteins interacting with the chemical Methadone from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
BAX BCL2-associated X protein
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYCS cytochrome c, somatic
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
INS insulin
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LEP leptin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
ORM2 orosomucoid 2
PLD2 phospholipase D2
PRL prolactin
TLR4 toll-like receptor 4
TNF tumor necrosis factor