Methemoglobinemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

134 genes co-occuring with the disease Methemoglobinemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CYB5R3 cytochrome b5 reductase 3 3.778
CYB5RL cytochrome b5 reductase-like 3.605
CYB5R4 cytochrome b5 reductase 4 3.575
CYB5R2 cytochrome b5 reductase 2 3.557
CYB5R1 cytochrome b5 reductase 1 3.551
CYB5A cytochrome b5 type A (microsomal) 3.121
G6PD glucose-6-phosphate dehydrogenase 3.117
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 2.957
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.942
HP haptoglobin 2.078
MB myoglobin 2.056
BLVRB biliverdin reductase B 2.055
MAOA monoamine oxidase A 1.937
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.869
HBB hemoglobin, beta 1.837
ALB albumin 1.832
XDH xanthine dehydrogenase 1.826
NQO1 NAD(P)H dehydrogenase, quinone 1 1.814
CYCS cytochrome c, somatic 1.8
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.732
MAOB monoamine oxidase B 1.722
GSR glutathione reductase 1.712
NOS3 nitric oxide synthase 3 (endothelial cell) 1.693
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.676
HBG1 hemoglobin, gamma A 1.666
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.664
COL17A1 collagen, type XVII, alpha 1 1.655
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.644
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.634
HBG2 hemoglobin, gamma G 1.593
TNF tumor necrosis factor 1.566
PDE5A phosphodiesterase 5A, cGMP-specific 1.561
CYGB cytoglobin 1.536
IL6 interleukin 6 1.529
F2 coagulation factor II (thrombin) 1.522
EPO erythropoietin 1.52
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.513
ACE2 angiotensin I converting enzyme 2 1.512
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.507
BCHE butyrylcholinesterase 1.501
HBA2 hemoglobin, alpha 2 1.491
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.483
PHC3 polyhomeotic homolog 3 (Drosophila) 1.482
NGB neuroglobin 1.475
IL1B interleukin 1, beta 1.474
BPGM 2,3-bisphosphoglycerate mutase 1.473
DST dystonin 1.472
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.465
GPX2 glutathione peroxidase 2 1.459
GPX7 glutathione peroxidase 7 1.458
TPMT thiopurine S-methyltransferase 1.455
GPX6 glutathione peroxidase 6 1.453
GPX5 glutathione peroxidase 5 1.451
GPX8 glutathione peroxidase 8 (putative) 1.451
HBA1 hemoglobin, alpha 1 1.44
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 1.434
GPX3 glutathione peroxidase 3 1.43
CRP C-reactive protein, pentraxin-related 1.421
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 1.409
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.408
NOS1 nitric oxide synthase 1 (neuronal) 1.383
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 1.377
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.354
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.336
INS insulin 1.336
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.333
HBE1 hemoglobin, epsilon 1 1.309
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.308
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.308
DHFR dihydrofolate reductase 1.296
CXCL8 chemokine (C-X-C motif) ligand 8 1.295
GPKOW G patch domain and KOW motifs 1.282
DHFR2 dihydrofolate reductase 2 1.28
AADAC arylacetamide deacetylase 1.279
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.272
HMOX1 heme oxygenase 1 1.271
ACE angiotensin I converting enzyme 1.266
CLIP4 CAP-GLY domain containing linker protein family, member 4 1.257
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.255
PARP1 poly (ADP-ribose) polymerase 1 1.255
IL1A interleukin 1, alpha 1.251
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.239
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 1.237
F3 coagulation factor III (thromboplastin, tissue factor) 1.234
DIPK1C divergent protein kinase domain 1C 1.229
EPOR erythropoietin receptor 1.223
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.206
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 1.205
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.194
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.191
EDN1 endothelin 1 1.181
TXN thioredoxin 1.176
CD4 CD4 molecule 1.174
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.169
MPO myeloperoxidase 1.169
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 1.165
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.154
HBD hemoglobin, delta 1.145
HPCAL4 hippocalcin like 4 1.133
POR P450 (cytochrome) oxidoreductase 1.127
IFNG interferon, gamma 1.124
SERF1A small EDRK-rich factor 1A (telomeric) 1.112
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.11
REN renin 1.108
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.098
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.097
NOS2 nitric oxide synthase 2, inducible 1.096
EPAS1 endothelial PAS domain protein 1 1.096
TP53 tumor protein p53 1.095
RRM2 ribonucleotide reductase M2 1.087
ABHD10 abhydrolase domain containing 10 1.081
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.07
UFC1 ubiquitin-fold modifier conjugating enzyme 1 1.07
EGLN1 egl-9 family hypoxia-inducible factor 1 1.069
SQOR sulfide quinone oxidoreductase 1.064
WEE2 WEE1 homolog 2 (S. pombe) 1.063
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.054
CKM creatine kinase, muscle 1.054
TMPRSS2 transmembrane protease, serine 2 1.052
IL10 interleukin 10 1.049
NFE2L2 nuclear factor, erythroid 2-like 2 1.041
RRM1 ribonucleotide reductase M1 1.04
CKB creatine kinase, brain 1.037
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.035
KEAP1 kelch-like ECH-associated protein 1 1.029
ZNF407 zinc finger protein 407 1.027
GGT7 gamma-glutamyltransferase 7 1.025
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.022
CKMT1B creatine kinase, mitochondrial 1B 1.021
AOX1 aldehyde oxidase 1 1.019
C11ORF58 chromosome 11 open reading frame 58 1.015
SHB Src homology 2 domain containing adaptor protein B 1.013
MYH14 myosin, heavy chain 14, non-muscle 1.011
PDF peptide deformylase (mitochondrial) 1.01