| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.330458 |
| PODXL | podocalyxin-like | 0.160384 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.152753 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.132524 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.103153 |
| LOXL2 | lysyl oxidase-like 2 | 0.098342 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0916593 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0875946 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.082274 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0814196 |
| VEGFA | vascular endothelial growth factor A | 0.07719 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.076868 |
| COL5A1 | collagen, type V, alpha 1 | 0.0701756 |
| COPA | coatomer protein complex, subunit alpha | 0.0701046 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0677014 |
| CALR | calreticulin | 0.0648232 |
| AHNAK | AHNAK nucleoprotein | 0.054454 |
| MSI2 | musashi RNA-binding protein 2 | 0.051582 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0503201 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0463833 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0441643 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0429037 |
| AUTS2 | autism susceptibility candidate 2 | 0.0420477 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.04157 |
| C1D | C1D nuclear receptor corepressor | 0.0385325 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0369759 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0362917 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0359376 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0355917 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0350641 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0346687 |
| EGFR | epidermal growth factor receptor | 0.0346666 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.03358 |
| GOLGA4 | golgin A4 | 0.0328771 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0324012 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0322151 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0321836 |
| CD109 | CD109 molecule | 0.0319198 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0316074 |
| DENND5A | DENN/MADD domain containing 5A | 0.0313407 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291836 |
| OGA | O-GlcNAcase | 0.0288794 |
| GOLGA2 | golgin A2 | 0.0286927 |
| APP | amyloid beta (A4) precursor protein | 0.0284735 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0283978 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0282605 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0280682 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0280046 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0278437 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0276806 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0271441 |
| B2M | beta-2-microglobulin | 0.0264211 |
| INSIG1 | insulin induced gene 1 | 0.0262341 |
| CDH13 | cadherin 13 | 0.026225 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0260822 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0260445 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0259341 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0258488 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.025655 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0253274 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0252873 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0252565 |
| RNF145 | ring finger protein 145 | 0.0249952 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0246887 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0242134 |
| ARF4 | ADP-ribosylation factor 4 | 0.0241838 |
| HELZ | helicase with zinc finger | 0.0241325 |
| RAB18 | RAB18, member RAS oncogene family | 0.0233793 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0232454 |
| SETD5 | SET domain containing 5 | 0.023244 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.023128 |
| UBTD2 | ubiquitin domain containing 2 | 0.0229896 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0229171 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0226329 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0224807 |
| AXL | AXL receptor tyrosine kinase | 0.022429 |
| CALU | calumenin | 0.0220487 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0220477 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0220294 |
| RREB1 | ras responsive element binding protein 1 | 0.021812 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0217617 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0216042 |
| RHOA | ras homolog family member A | 0.0214311 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0213063 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0213043 |
| DST | dystonin | 0.0212677 |
| CANX | calnexin | 0.0209993 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0208441 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0206737 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.020631 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0205629 |
| NID1 | nidogen 1 | 0.0204719 |
| NUP58 | nucleoporin 58 | 0.0204384 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0203054 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0202988 |
| SNX13 | sorting nexin 13 | 0.0198132 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0197468 |
| HDAC9 | histone deacetylase 9 | 0.0196713 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0195462 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0194313 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246996 |
| MT2A | metallothionein 2A | -0.183702 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.180604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112111 |
| TMSB10 | thymosin beta 10 | -0.103384 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.091144 |
| NDRG1 | N-myc downstream regulated 1 | -0.0844967 |
| LOX | lysyl oxidase | -0.0800138 |
| PLAT | plasminogen activator, tissue | -0.065665 |
| COL5A2 | collagen, type V, alpha 2 | -0.0653033 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0639056 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0632935 |
| S100A10 | S100 calcium binding protein A10 | -0.0628192 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0619644 |
| COL3A1 | collagen, type III, alpha 1 | -0.0571372 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0539241 |
| STC1 | stanniocalcin 1 | -0.0526304 |
| CD44 | CD44 molecule (Indian blood group) | -0.0520634 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.049773 |
| CENPF | centromere protein F, 350/400kDa | -0.0493015 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0482947 |
| COL1A2 | collagen, type I, alpha 2 | -0.0469605 |
| S100A6 | S100 calcium binding protein A6 | -0.0467446 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0458429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0447708 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0446103 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0442985 |
| SVIL | supervillin | -0.0420198 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.040669 |
| SQSTM1 | sequestosome 1 | -0.0396574 |
| SEPTIN7 | septin 7 | -0.0386757 |
| MT1X | metallothionein 1X | -0.0385699 |
| RPS2 | ribosomal protein S2 | -0.0384335 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.038218 |
| LMNA | lamin A/C | -0.037364 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0369946 |
| RPS24 | ribosomal protein S24 | -0.0369904 |
| FSTL1 | follistatin-like 1 | -0.0369264 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0365182 |
| RPS8 | ribosomal protein S8 | -0.0361537 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0357619 |
| TRIM56 | tripartite motif containing 56 | -0.0353666 |
| ASPH | aspartate beta-hydroxylase | -0.0350627 |
| SMYD3 | SET and MYND domain containing 3 | -0.0348393 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0339228 |
| RPL28 | ribosomal protein L28 | -0.0336775 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0335729 |
| CD99 | CD99 molecule | -0.0334375 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0317608 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0306451 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0303105 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300186 |
| EFNA5 | ephrin-A5 | -0.0296361 |
| IL6ST | interleukin 6 signal transducer | -0.0294538 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0294503 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0291067 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0290444 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0287729 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0285558 |
| RPL23 | ribosomal protein L23 | -0.0283112 |
| CSTB | cystatin B (stefin B) | -0.0282453 |
| RPL37A | ribosomal protein L37a | -0.0278645 |
| MPZL1 | myelin protein zero-like 1 | -0.0278307 |
| S100A4 | S100 calcium binding protein A4 | -0.0276569 |
| LDHA | lactate dehydrogenase A | -0.0276391 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0275115 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0274698 |
| ZNF207 | zinc finger protein 207 | -0.0273172 |
| SDC4 | syndecan 4 | -0.0272315 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0272044 |
| PKM | pyruvate kinase, muscle | -0.0269468 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0266082 |
| HLA-C | major histocompatibility complex, class I, C | -0.0263382 |
| TDRD7 | tudor domain containing 7 | -0.0262517 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0262297 |
| RPL12 | ribosomal protein L12 | -0.025874 |
| RPL34 | ribosomal protein L34 | -0.0258337 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0258241 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0257853 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.025693 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0256671 |
| TAGLN2 | transgelin 2 | -0.0256146 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0254646 |
| PLSCR1 | phospholipid scramblase 1 | -0.0253894 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0252827 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0252288 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0251347 |
| RNF213 | ring finger protein 213 | -0.0248285 |
| RIGI | RNA sensor RIG-I | -0.0246397 |
| ACTG1 | actin gamma 1 | -0.024558 |
| RPL36 | ribosomal protein L36 | -0.0244986 |
| RPL9 | ribosomal protein L9 | -0.0241255 |
| SP3 | Sp3 transcription factor | -0.0236926 |
| PRELID2 | PRELI domain containing 2 | -0.0235017 |
| OSMR | oncostatin M receptor | -0.0233484 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0233025 |
| MX2 | MX dynamin-like GTPase 2 | -0.0232046 |
| RPL38 | ribosomal protein L38 | -0.0231829 |
| KLF6 | Kruppel-like factor 6 | -0.0230894 |
| RPL32 | ribosomal protein L32 | -0.0230564 |
