| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.192593 |
| TMEM41B | transmembrane protein 41B | 0.0594346 |
| TXNRD1 | thioredoxin reductase 1 | 0.0388264 |
| ECT2 | epithelial cell transforming 2 | 0.0351417 |
| KIF5B | kinesin family member 5B | 0.0327612 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0315304 |
| OXR1 | oxidation resistance 1 | 0.0308006 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0298576 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0286998 |
| YBX1 | Y box binding protein 1 | 0.0281572 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0280165 |
| RTN4 | reticulon 4 | 0.0270146 |
| PNN | pinin, desmosome associated protein | 0.0265871 |
| CEP95 | centrosomal protein 95kDa | 0.0260841 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0256974 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0251408 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0237271 |
| ATP11A | ATPase, class VI, type 11A | 0.0235425 |
| VCL | vinculin | 0.0231279 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.022984 |
| WDR43 | WD repeat domain 43 | 0.0227993 |
| TPR | translocated promoter region, nuclear basket protein | 0.0227221 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0220162 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0216308 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0213968 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0212333 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.021072 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0206053 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0205912 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0202252 |
| MKI67 | marker of proliferation Ki-67 | 0.0200912 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0198021 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0197932 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0197596 |
| TNPO1 | transportin 1 | 0.0190222 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0188691 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0183558 |
| CPOX | coproporphyrinogen oxidase | 0.0182616 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0182371 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0182061 |
| KLC1 | kinesin light chain 1 | 0.0180306 |
| CCNL1 | cyclin L1 | 0.0179027 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0176742 |
| ETNK1 | ethanolamine kinase 1 | 0.0175684 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0170765 |
| CEP192 | centrosomal protein 192kDa | 0.016752 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0166948 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0165954 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0164674 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.0163583 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0162697 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0162675 |
| SSRP1 | structure specific recognition protein 1 | 0.0161955 |
| PRKCI | protein kinase C, iota | 0.016127 |
| CEP70 | centrosomal protein 70kDa | 0.0160441 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0159978 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0159316 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.015878 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0158261 |
| SBF2 | SET binding factor 2 | 0.0156946 |
| THOC1 | THO complex 1 | 0.0156729 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0155869 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0155854 |
| RPL26 | ribosomal protein L26 | 0.0155064 |
| SP3 | Sp3 transcription factor | 0.0153168 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0153096 |
| NEK7 | NIMA-related kinase 7 | 0.0151761 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0151101 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.015087 |
| YME1L1 | YME1-like 1 ATPase | 0.0150018 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0148446 |
| RPS18 | ribosomal protein S18 | 0.0147545 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0142284 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0142234 |
| THOC2 | THO complex 2 | 0.0141886 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0141667 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.014142 |
| BARD1 | BRCA1 associated RING domain 1 | 0.0140234 |
| PTMS | parathymosin | 0.0138744 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0137486 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0137434 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.013684 |
| PCM1 | pericentriolar material 1 | 0.0134737 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0134352 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0133806 |
| MICU3 | mitochondrial calcium uptake family, member 3 | 0.0133031 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0132244 |
| MPG | N-methylpurine-DNA glycosylase | 0.0131204 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0131178 |
| WRN | Werner syndrome, RecQ helicase-like | 0.012981 |
| CENPF | centromere protein F, 350/400kDa | 0.012841 |
| RBM25 | RNA binding motif protein 25 | 0.0127068 |
| CASC3 | cancer susceptibility candidate 3 | 0.0126807 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0126566 |
| DIAPH1 | diaphanous-related formin 1 | 0.01261 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0124524 |
| ETV5 | ets variant 5 | 0.0123921 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0123717 |
| CDCA2 | cell division cycle associated 2 | 0.0123584 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0123551 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.172529 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.155927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152505 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.132738 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.113779 |
| HMGA2 | high mobility group AT-hook 2 | -0.0993625 |
| PCDH7 | protocadherin 7 | -0.0814049 |
| EHBP1 | EH domain binding protein 1 | -0.0764164 |
| ACTG1 | actin gamma 1 | -0.0662293 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0660256 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0587057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0583962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0532656 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0513899 |
| TMSB10 | thymosin beta 10 | -0.0507183 |
| ASPH | aspartate beta-hydroxylase | -0.0492495 |
| NHSL1 | NHS-like 1 | -0.0485647 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0474756 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0467148 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0460211 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0421463 |
| RASAL2 | RAS protein activator like 2 | -0.0417146 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0406356 |
| ADIPOR2 | adiponectin receptor 2 | -0.0403086 |
| INTS6 | integrator complex subunit 6 | -0.0397723 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0390857 |
| PCDH9 | protocadherin 9 | -0.0388279 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0377962 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377753 |
| CUX1 | cut-like homeobox 1 | -0.0369209 |
| ANXA1 | annexin A1 | -0.0361525 |
| VIM | vimentin | -0.0361294 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0354131 |
| YAP1 | Yes-associated protein 1 | -0.0347665 |
| PTMA | prothymosin, alpha | -0.0342202 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0340231 |
| ZNF804A | zinc finger protein 804A | -0.034007 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0339595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330938 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0330374 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0329663 |
| CANX | calnexin | -0.0328596 |
| EGR1 | early growth response 1 | -0.03261 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0323088 |
| HDAC9 | histone deacetylase 9 | -0.0321513 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320592 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0319917 |
| DST | dystonin | -0.0319611 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0317248 |
| DTNA | dystrobrevin, alpha | -0.0316821 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0315973 |
| LRRC23 | leucine rich repeat containing 23 | -0.0313315 |
| PGK1 | phosphoglycerate kinase 1 | -0.030863 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0308286 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304668 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0301919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0300984 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0294974 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0293468 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287443 |
| CALR | calreticulin | -0.0286943 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0286463 |
| TPI1 | triosephosphate isomerase 1 | -0.0285063 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0283447 |
| S100A10 | S100 calcium binding protein A10 | -0.0283198 |
| LDHA | lactate dehydrogenase A | -0.0276462 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0275991 |
| GNAS | GNAS complex locus | -0.027492 |
| SYT1 | synaptotagmin I | -0.026604 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0262796 |
| FSTL5 | follistatin-like 5 | -0.0256802 |
| JMJD1C | jumonji domain containing 1C | -0.0256225 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0254123 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254104 |
| CCND1 | cyclin D1 | -0.025298 |
| DENND5A | DENN/MADD domain containing 5A | -0.0250546 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0249335 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0248898 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0239454 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0238632 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0238267 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0235433 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0235074 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0233742 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0232586 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0229327 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0227761 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0227088 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0226732 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0226287 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0225531 |
| TUBA1B | tubulin, alpha 1b | -0.0224744 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0224452 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0223589 |
| TPM4 | tropomyosin 4 | -0.0217716 |
| NEBL | nebulette | -0.021653 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0214636 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0214341 |
| CMIP | c-Maf inducing protein | -0.0214313 |
| KSR2 | kinase suppressor of ras 2 | -0.0211935 |
