| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.141203 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0459963 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0426381 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0355101 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0307584 |
| TSC22D2 | TSC22 domain family, member 2 | 0.029356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0286256 |
| SPAG9 | sperm associated antigen 9 | 0.0282815 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0282486 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0269997 |
| FAM13A | family with sequence similarity 13, member A | 0.0253 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0234461 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.021949 |
| ZNF292 | zinc finger protein 292 | 0.020157 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0195018 |
| NDRG1 | N-myc downstream regulated 1 | 0.0194271 |
| VEGFA | vascular endothelial growth factor A | 0.0188958 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0175245 |
| NUP58 | nucleoporin 58 | 0.0158495 |
| CSTB | cystatin B (stefin B) | 0.0156568 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0155339 |
| MXD1 | MAX dimerization protein 1 | 0.0152942 |
| ADM | adrenomedullin | 0.0150366 |
| LMTK2 | lemur tyrosine kinase 2 | 0.014994 |
| NPTN | neuroplastin | 0.013826 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0138034 |
| QKI | QKI, KH domain containing, RNA binding | 0.0137728 |
| USP3 | ubiquitin specific peptidase 3 | 0.0135855 |
| SEC24A | SEC24 family member A | 0.0133177 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0131669 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0129446 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0129211 |
| RNF145 | ring finger protein 145 | 0.0127955 |
| CCNL1 | cyclin L1 | 0.0125822 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0125391 |
| RPS2 | ribosomal protein S2 | 0.0124491 |
| ANXA5 | annexin A5 | 0.0118131 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0116305 |
| CRY1 | cryptochrome circadian clock 1 | 0.0114447 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0113596 |
| RPS6 | ribosomal protein S6 | 0.0113201 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0113168 |
| DUSP12 | dual specificity phosphatase 12 | 0.0112967 |
| AFTPH | aftiphilin | 0.0109674 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0106924 |
| ANXA1 | annexin A1 | 0.0105544 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0104647 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0104298 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0103967 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0103532 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0102269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0101445 |
| RCOR1 | REST corepressor 1 | 0.010132 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0100336 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.00988616 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00962503 |
| TPD52 | tumor protein D52 | 0.00950025 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.00940182 |
| ARRDC3 | arrestin domain containing 3 | 0.008896 |
| RPS7 | ribosomal protein S7 | 0.00875025 |
| MED26 | mediator complex subunit 26 | 0.00874917 |
| SULF2 | sulfatase 2 | 0.0086787 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0086601 |
| ZFP36 | ZFP36 ring finger protein | 0.00862287 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0083467 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.00826477 |
| MEF2A | myocyte enhancer factor 2A | 0.00822989 |
| ARF4 | ADP-ribosylation factor 4 | 0.00816379 |
| RYBP | RING1 and YY1 binding protein | 0.0081182 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00809726 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00803314 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00777764 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00770744 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00758763 |
| MACO1 | macoilin 1 | 0.00757958 |
| FAM13B | family with sequence similarity 13, member B | 0.00754824 |
| CASC3 | cancer susceptibility candidate 3 | 0.00751082 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00733679 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00730518 |
| RNF38 | ring finger protein 38 | 0.00729822 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.00720697 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00720131 |
| HPCAL1 | hippocalcin-like 1 | 0.0070041 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00696956 |
| OXSR1 | oxidative stress responsive 1 | 0.00688877 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00687131 |
| ANKRD37 | ankyrin repeat domain 37 | 0.00682993 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.00679427 |
| DMXL1 | Dmx-like 1 | 0.00679263 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00674824 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00672137 |
| HDAC3 | histone deacetylase 3 | 0.00670837 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00668971 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00668479 |
| PRKCI | protein kinase C, iota | 0.0066351 |
| CRYBG2 | crystallin beta-gamma domain containing 2 | 0.00663452 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00662431 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.0066239 |
| RPS26 | ribosomal protein S26 | 0.00661822 |
| HELZ | helicase with zinc finger | 0.00661545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.275949 |
| TMSB10 | thymosin beta 10 | -0.188862 |
| VIM | vimentin | -0.135025 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.132324 |
| AHNAK | AHNAK nucleoprotein | -0.125647 |
| FLNB | filamin B, beta | -0.117941 |
| ASPH | aspartate beta-hydroxylase | -0.112786 |
| EGFR | epidermal growth factor receptor | -0.105131 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0920294 |
| TXNRD1 | thioredoxin reductase 1 | -0.0873584 |
| LAMB3 | laminin, beta 3 | -0.0797427 |
| EFNA5 | ephrin-A5 | -0.0765327 |
| RPS27A | ribosomal protein S27a | -0.0761627 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0740354 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.063796 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0608169 |
| SMAD3 | SMAD family member 3 | -0.0584227 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0571807 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0570026 |
| SDC4 | syndecan 4 | -0.0564031 |
| PCBP2 | poly(rC) binding protein 2 | -0.0558427 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0556571 |
| MCL1 | myeloid cell leukemia 1 | -0.0507589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502926 |
| LMO7 | LIM domain 7 | -0.0502079 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0493557 |
| EMP1 | epithelial membrane protein 1 | -0.0489864 |
| LDHA | lactate dehydrogenase A | -0.0482001 |
| ACTG1 | actin gamma 1 | -0.0465659 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0464877 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0459074 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0453034 |
| KRT8 | keratin 8, type II | -0.0450863 |
| ANTXR2 | anthrax toxin receptor 2 | -0.044841 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0427658 |
| PERP | PERP, TP53 apoptosis effector | -0.0426252 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0426227 |
| HMGA2 | high mobility group AT-hook 2 | -0.0423664 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0411817 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0402162 |
| MUC17 | mucin 17, cell surface associated | -0.0398549 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0396379 |
| RPL23 | ribosomal protein L23 | -0.039206 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0386902 |
| TRRAP | transformation/transcription domain-associated protein | -0.0385165 |
| S100A6 | S100 calcium binding protein A6 | -0.0384647 |
| SLC38A2 | solute carrier family 38, member 2 | -0.038064 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.038019 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0377585 |
| NPSR1 | neuropeptide S receptor 1 | -0.0365817 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.036567 |
| ACTN4 | actinin, alpha 4 | -0.0365095 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0361402 |
| ENO1 | enolase 1, (alpha) | -0.0360899 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0354013 |
| TPM4 | tropomyosin 4 | -0.0353854 |
| EHBP1 | EH domain binding protein 1 | -0.0350039 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0345353 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0342948 |
| EZR | ezrin | -0.0334814 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0334579 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.033324 |
| VCAN | versican | -0.0331827 |
| ITGA6 | integrin, alpha 6 | -0.0331257 |
| RPS3 | ribosomal protein S3 | -0.0330615 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0328745 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0328615 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0327638 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0321229 |
| LAMA4 | laminin, alpha 4 | -0.0319824 |
| PGK1 | phosphoglycerate kinase 1 | -0.0318331 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0318109 |
| CAB39 | calcium binding protein 39 | -0.0314437 |
| PRELID2 | PRELI domain containing 2 | -0.0313078 |
| PKM | pyruvate kinase, muscle | -0.0311904 |
| DSG2 | desmoglein 2 | -0.0306795 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0306092 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.030523 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0304797 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0302465 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302224 |
| USP34 | ubiquitin specific peptidase 34 | -0.0300497 |
| KLF6 | Kruppel-like factor 6 | -0.0298459 |
| TPM3 | tropomyosin 3 | -0.0293975 |
| SQSTM1 | sequestosome 1 | -0.0293921 |
| PARD3 | par-3 family cell polarity regulator | -0.0292084 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0291994 |
| HMGA1 | high mobility group AT-hook 1 | -0.0290775 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0290358 |
| TAOK3 | TAO kinase 3 | -0.0289471 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0287688 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0282376 |
| HDLBP | high density lipoprotein binding protein | -0.0281639 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0280313 |
| CDCP1 | CUB domain containing protein 1 | -0.027985 |
| FOXO1 | forkhead box O1 | -0.027899 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0278502 |
| OSMR | oncostatin M receptor | -0.0276478 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0273591 |
| MYOF | myoferlin | -0.0272308 |
