| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.0691993 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0661186 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0539609 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0303514 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0301632 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0296763 |
| OSMR | oncostatin M receptor | 0.0291127 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287951 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0266228 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0249214 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241775 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0239336 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.023529 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0233732 |
| NTN4 | netrin 4 | 0.0227584 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0220942 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.02183 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0217147 |
| CCNL1 | cyclin L1 | 0.0216466 |
| KIAA1217 | KIAA1217 | 0.0214352 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0208003 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0203743 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0200877 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0195199 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0183435 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0181547 |
| GSE1 | Gse1 coiled-coil protein | 0.0179219 |
| MYO1B | myosin IB | 0.0177869 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0170377 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0165905 |
| CAB39 | calcium binding protein 39 | 0.0165275 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.016526 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0163534 |
| MLPH | melanophilin | 0.0161822 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0161488 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0158054 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.0157955 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0153005 |
| TENM2 | teneurin transmembrane protein 2 | 0.0152591 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0151009 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0150249 |
| NPC1 | Niemann-Pick disease, type C1 | 0.015023 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0148651 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0148601 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0148093 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0147089 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0143225 |
| DUSP16 | dual specificity phosphatase 16 | 0.0142563 |
| KAZN | kazrin, periplakin interacting protein | 0.014218 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0137177 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0136844 |
| SETX | senataxin | 0.0133321 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | 0.0131692 |
| S100A8 | S100 calcium binding protein A8 | 0.0131035 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0130771 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0128849 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0127326 |
| TPM1 | tropomyosin 1 (alpha) | 0.0126539 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0123184 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0122428 |
| NRCAM | neuronal cell adhesion molecule | 0.0120377 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0117018 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.011569 |
| AREG | amphiregulin | 0.0114074 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0111419 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0107944 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0107467 |
| WWOX | WW domain containing oxidoreductase | 0.010719 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0106767 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.010543 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0104432 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0103963 |
| GLCCI1 | glucocorticoid induced 1 | 0.0103952 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0102771 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0102597 |
| VCL | vinculin | 0.0101441 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0101319 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0101306 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00969616 |
| TMSB4X | thymosin beta 4, X-linked | 0.00969514 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00959802 |
| ANKRD36C | ankyrin repeat domain 36C | 0.00959695 |
| CFB | complement factor B | 0.00953517 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00947565 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.00942018 |
| STK17A | serine/threonine kinase 17a | 0.00940004 |
| FNDC3A | fibronectin type III domain containing 3A | 0.00922221 |
| BCL2L1 | BCL2-like 1 | 0.00908236 |
| UBAP1 | ubiquitin associated protein 1 | 0.00881613 |
| MED13L | mediator complex subunit 13-like | 0.00878705 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.00868764 |
| ANKRD30A | ankyrin repeat domain 30A | 0.00866794 |
| S100A7 | S100 calcium binding protein A7 | 0.00862186 |
| COPA | coatomer protein complex, subunit alpha | 0.00850666 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00845122 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00829041 |
| RPS18 | ribosomal protein S18 | 0.00828469 |
| INSR | insulin receptor | 0.00822508 |
| BICDL1 | BICD family like cargo adaptor 1 | 0.00820394 |
| LOXL2 | lysyl oxidase-like 2 | 0.00814555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.181233 |
| RPL19 | ribosomal protein L19 | -0.134868 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0728443 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0641609 |
| NDRG1 | N-myc downstream regulated 1 | -0.0517607 |
| ACTG1 | actin gamma 1 | -0.0491747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0434608 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.041773 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0410371 |
| TMEM123 | transmembrane protein 123 | -0.0367333 |
| INTS6 | integrator complex subunit 6 | -0.0347434 |
| ENO1 | enolase 1, (alpha) | -0.0338249 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0321074 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0313741 |
| DTNA | dystrobrevin, alpha | -0.0297427 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0290583 |
| PTMA | prothymosin, alpha | -0.0283031 |
| LASP1 | LIM and SH3 protein 1 | -0.0278578 |
| NCOA3 | nuclear receptor coactivator 3 | -0.027452 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0269308 |
| ASPH | aspartate beta-hydroxylase | -0.0264442 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0261158 |
| RPL35A | ribosomal protein L35a | -0.0258292 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0257139 |
| CDK12 | cyclin-dependent kinase 12 | -0.025331 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0248405 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0242718 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0242467 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0242126 |
| SBF2 | SET binding factor 2 | -0.0240695 |
| DENND1A | DENN/MADD domain containing 1A | -0.0239806 |
| LDHA | lactate dehydrogenase A | -0.0239483 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0232169 |
| SP100 | SP100 nuclear antigen | -0.0229334 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0222648 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0220876 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0219295 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0217394 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0214681 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0213258 |
| RPS8 | ribosomal protein S8 | -0.0213113 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0212162 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0205515 |
| RPL37A | ribosomal protein L37a | -0.020495 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0203216 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0202176 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0201315 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0199444 |
| TMSB10 | thymosin beta 10 | -0.0199374 |
| RPS3 | ribosomal protein S3 | -0.0198147 |
| RTN3 | reticulon 3 | -0.0198073 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0197198 |
| PGK1 | phosphoglycerate kinase 1 | -0.0196933 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0193647 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0192161 |
| ZNF292 | zinc finger protein 292 | -0.0190159 |
| RPL12 | ribosomal protein L12 | -0.0190018 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0186523 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.018521 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0182608 |
| MBD4 | methyl-CpG binding domain protein 4 | -0.0181454 |
| RAD51B | RAD51 paralog B | -0.0181094 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0179744 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0179012 |
| LOC112694756 | uncharaterized LOC112694756 | -0.017795 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0177551 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0177263 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0177188 |
| TUBA1B | tubulin, alpha 1b | -0.0175684 |
| BBX | bobby sox homolog (Drosophila) | -0.0170822 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.017034 |
| PARD3 | par-3 family cell polarity regulator | -0.0168827 |
| PKM | pyruvate kinase, muscle | -0.0166859 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.01662 |
| RPS24 | ribosomal protein S24 | -0.016587 |
| PRR11 | proline rich 11 | -0.0165179 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0162962 |
| PLSCR2 | phospholipid scramblase 2 | -0.016261 |
| ANLN | anillin, actin binding protein | -0.0162294 |
| FAM13A | family with sequence similarity 13, member A | -0.0161526 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0161333 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0160801 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.016001 |
| PRELID2 | PRELI domain containing 2 | -0.0159915 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0158722 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0158113 |
| DEK | DEK proto-oncogene | -0.0157099 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0154055 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0153397 |
| CLTC | clathrin, heavy chain (Hc) | -0.0152718 |
| GNAS | GNAS complex locus | -0.01521 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.0151823 |
| LMNA | lamin A/C | -0.0151229 |
| SLFN5 | schlafen family member 5 | -0.0150122 |
| CCNY | cyclin Y | -0.0148497 |
| CCND1 | cyclin D1 | -0.01472 |
| RPL34 | ribosomal protein L34 | -0.0147174 |
| RPS6 | ribosomal protein S6 | -0.0146127 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.014586 |
| DSTN | destrin (actin depolymerizing factor) | -0.0144303 |
