| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.114773 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0835057 |
| CD109 | CD109 molecule | 0.0771718 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0765525 |
| COPA | coatomer protein complex, subunit alpha | 0.0714883 |
| RNF145 | ring finger protein 145 | 0.0710311 |
| VEGFA | vascular endothelial growth factor A | 0.0695967 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0665815 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0598336 |
| SETD5 | SET domain containing 5 | 0.057928 |
| NUP58 | nucleoporin 58 | 0.0572736 |
| CABIN1 | calcineurin binding protein 1 | 0.0566048 |
| NDRG1 | N-myc downstream regulated 1 | 0.0554548 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0532614 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0517871 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0515808 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0452941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0430104 |
| TPR | translocated promoter region, nuclear basket protein | 0.0415621 |
| GOLGA4 | golgin A4 | 0.0410577 |
| VMP1 | vacuole membrane protein 1 | 0.0405817 |
| CALD1 | caldesmon 1 | 0.0385866 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0376369 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0368354 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0364352 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0349619 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0346638 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0339953 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0330963 |
| POTEF | POTE ankyrin domain family, member F | 0.0327973 |
| CALR | calreticulin | 0.0323252 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0321328 |
| YBX1 | Y box binding protein 1 | 0.0310221 |
| CCNL1 | cyclin L1 | 0.0305218 |
| GDF15 | growth differentiation factor 15 | 0.0297268 |
| NBAS | neuroblastoma amplified sequence | 0.0296651 |
| MRTFA | myocardin related transcription factor A | 0.0289322 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0289107 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0286661 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285201 |
| PHF21A | PHD finger protein 21A | 0.0281952 |
| PKM | pyruvate kinase, muscle | 0.028145 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0274628 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0267769 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0262056 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0261551 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0260342 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0257012 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0256873 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0255839 |
| FOSL1 | FOS-like antigen 1 | 0.02506 |
| CUL3 | cullin 3 | 0.0249044 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0248238 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0246175 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0242109 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0237544 |
| RHOA | ras homolog family member A | 0.023605 |
| PLIN2 | perilipin 2 | 0.0233099 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0231971 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0230844 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0230525 |
| EP300 | E1A binding protein p300 | 0.0229665 |
| PTMS | parathymosin | 0.0228105 |
| CDK19 | cyclin-dependent kinase 19 | 0.0226534 |
| LNPK | lunapark, ER junction formation factor | 0.0220284 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0218792 |
| PTK2 | protein tyrosine kinase 2 | 0.0218094 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0216007 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0215714 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0212528 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0210588 |
| CTTNBP2 | cortactin binding protein 2 | 0.0210143 |
| TMEM255B | transmembrane protein 255B | 0.0209654 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020957 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0208555 |
| FBXO7 | F-box protein 7 | 0.0207681 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0206899 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0205856 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0205342 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0204338 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0202828 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.020276 |
| PTMA | prothymosin, alpha | 0.0202258 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0202128 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0201498 |
| INSIG2 | insulin induced gene 2 | 0.0199518 |
| ZNF292 | zinc finger protein 292 | 0.0198437 |
| ZYX | zyxin | 0.0198108 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0196793 |
| RPL3 | ribosomal protein L3 | 0.019626 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0195528 |
| CDC73 | cell division cycle 73 | 0.0195108 |
| SET | SET nuclear proto-oncogene | 0.0194417 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0193925 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0193151 |
| SNX13 | sorting nexin 13 | 0.0193049 |
| HELZ | helicase with zinc finger | 0.0192943 |
| TOP1 | topoisomerase (DNA) I | 0.0188062 |
| WDR43 | WD repeat domain 43 | 0.0187215 |
| B2M | beta-2-microglobulin | 0.018499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.215121 |
| FN1 | fibronectin 1 | -0.182235 |
| GPC6 | glypican 6 | -0.15567 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147549 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.141982 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.135748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12414 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.121086 |
| TNNC1 | troponin C type 1 (slow) | -0.0902898 |
| VGF | VGF nerve growth factor inducible | -0.0834677 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0702595 |
| FMN1 | formin 1 | -0.0662367 |
| VIM | vimentin | -0.0595376 |
| FRMD4A | FERM domain containing 4A | -0.0588949 |
| HMCN1 | hemicentin 1 | -0.0558825 |
| MACROD2 | MACRO domain containing 2 | -0.0532414 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0522923 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0505859 |
| PDE10A | phosphodiesterase 10A | -0.0490634 |
| PCDH7 | protocadherin 7 | -0.0478596 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0458494 |
| IER3 | immediate early response 3 | -0.0439138 |
| OSMR | oncostatin M receptor | -0.0425448 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0420448 |
| PGK1 | phosphoglycerate kinase 1 | -0.0416783 |
| ACTG1 | actin gamma 1 | -0.0412409 |
| CDK14 | cyclin-dependent kinase 14 | -0.0396575 |
| NAV3 | neuron navigator 3 | -0.038874 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0386528 |
| TMSB10 | thymosin beta 10 | -0.0385939 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0385334 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0384623 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0382345 |
| A2M | alpha-2-macroglobulin | -0.0379676 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0376042 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0370109 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0359692 |
| FBXO32 | F-box protein 32 | -0.0358431 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0352376 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.034818 |
| SDC2 | syndecan 2 | -0.0344552 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0342336 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0335334 |
| NBEA | neurobeachin | -0.0329825 |
| FRMD5 | FERM domain containing 5 | -0.0327377 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0325924 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0320328 |
| NHSL1 | NHS-like 1 | -0.0314814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0314368 |
| EXOC4 | exocyst complex component 4 | -0.0312436 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0307419 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0304776 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299196 |
| FHIT | fragile histidine triad | -0.029236 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0282752 |
| AHNAK | AHNAK nucleoprotein | -0.0282228 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0281777 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.027636 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.027367 |
| NLGN1 | neuroligin 1 | -0.0268361 |
| NRCAM | neuronal cell adhesion molecule | -0.0267584 |
| PAX3 | paired box 3 | -0.026719 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0266914 |
| MT1X | metallothionein 1X | -0.0266261 |
| SMYD3 | SET and MYND domain containing 3 | -0.0265561 |
| EHBP1 | EH domain binding protein 1 | -0.0263406 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0262287 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0255936 |
| NPR2 | natriuretic peptide receptor 2 | -0.0254252 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0251525 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0250786 |
| DOCK4 | dedicator of cytokinesis 4 | -0.02497 |
| HMGA2 | high mobility group AT-hook 2 | -0.0248588 |
| ATF6 | activating transcription factor 6 | -0.0247736 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0242569 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0242186 |
| RPLP1 | ribosomal protein, large, P1 | -0.0240072 |
| RUNX1 | runt-related transcription factor 1 | -0.0239015 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.023541 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0232777 |
| HLA-E | major histocompatibility complex, class I, E | -0.0232289 |
| GNAS | GNAS complex locus | -0.023187 |
| MITF | microphthalmia-associated transcription factor | -0.0231161 |
| ETV6 | ets variant 6 | -0.0230206 |
| AFAP1 | actin filament associated protein 1 | -0.0229704 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229525 |
| CDH19 | cadherin 19, type 2 | -0.0228521 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0226003 |
| HBP1 | HMG-box transcription factor 1 | -0.0223412 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0221723 |
| ATXN1 | ataxin 1 | -0.0221611 |
| PTCHD4 | patched domain containing 4 | -0.0219785 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0219139 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0211997 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0207546 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0207486 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0207003 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0206924 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0206909 |
| COL1A2 | collagen, type I, alpha 2 | -0.0205272 |