| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LPIN1 | lipin 1 | 0.0570002 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0346853 |
| PLAT | plasminogen activator, tissue | 0.034412 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0285186 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0265136 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249585 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0235919 |
| PTK2 | protein tyrosine kinase 2 | 0.0229046 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0221807 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.021325 |
| OGA | O-GlcNAcase | 0.0202423 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.019253 |
| AOPEP | aminopeptidase O (putative) | 0.0186685 |
| FNDC3B | fibronectin type III domain containing 3B | 0.018661 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.018598 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0182097 |
| WDR43 | WD repeat domain 43 | 0.0175963 |
| GPC5 | glypican 5 | 0.0175266 |
| CENPF | centromere protein F, 350/400kDa | 0.0172063 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0160905 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.015371 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0153145 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0153123 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0152229 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0150285 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0149322 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0148065 |
| PCNX1 | pecanex 1 | 0.0146737 |
| DST | dystonin | 0.0145811 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0145439 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0144055 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0141397 |
| PUM2 | pumilio RNA-binding family member 2 | 0.014138 |
| CEP95 | centrosomal protein 95kDa | 0.0138898 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0138093 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0136431 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0135311 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.01329 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0131879 |
| KIF5B | kinesin family member 5B | 0.0131457 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0131447 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0130196 |
| SMAD3 | SMAD family member 3 | 0.0129079 |
| ENAH | enabled homolog (Drosophila) | 0.0127896 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0127607 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0127285 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0126984 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0125375 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0124517 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0124227 |
| SPAG9 | sperm associated antigen 9 | 0.0124152 |
| VEGFA | vascular endothelial growth factor A | 0.0123142 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0121333 |
| SERINC1 | serine incorporator 1 | 0.011986 |
| MEIS2 | Meis homeobox 2 | 0.011967 |
| DNMBP | dynamin binding protein | 0.0116641 |
| RANBP2 | RAN binding protein 2 | 0.0113018 |
| RBM25 | RNA binding motif protein 25 | 0.0112834 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0112531 |
| SLMAP | sarcolemma associated protein | 0.0112294 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0112212 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0111244 |
| CDK19 | cyclin-dependent kinase 19 | 0.011011 |
| ARRDC3 | arrestin domain containing 3 | 0.0109463 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0109342 |
| AHNAK | AHNAK nucleoprotein | 0.0109237 |
| FOXO3 | forkhead box O3 | 0.0108593 |
| HAS2 | hyaluronan synthase 2 | 0.0107659 |
| APP | amyloid beta (A4) precursor protein | 0.0107294 |
| TRIM37 | tripartite motif containing 37 | 0.0106593 |
| XPO1 | exportin 1 | 0.0105651 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0105602 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0105405 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0105037 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.0103731 |
| KLHL13 | kelch-like family member 13 | 0.0103608 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0103436 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0103413 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0103123 |
| SNX13 | sorting nexin 13 | 0.0102425 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0102368 |
| SUCO | SUN domain containing ossification factor | 0.0101599 |
| YME1L1 | YME1-like 1 ATPase | 0.010147 |
| YTHDC1 | YTH domain containing 1 | 0.0101294 |
| MYO6 | myosin VI | 0.0101288 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0100305 |
| CLTC | clathrin, heavy chain (Hc) | 0.00991116 |
| TOP1 | topoisomerase (DNA) I | 0.00986481 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.00984021 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.00976819 |
| YEATS2 | YEATS domain containing 2 | 0.00975893 |
| HMGB2 | high mobility group box 2 | 0.00968441 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.00967589 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00965542 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00959803 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.00952472 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.00946913 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00941163 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.00939102 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.00936582 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.141146 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109802 |
| VIM | vimentin | -0.0647494 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0588887 |
| VCL | vinculin | -0.0578479 |
| LSAMP | limbic system-associated membrane protein | -0.0496226 |
| NDRG1 | N-myc downstream regulated 1 | -0.0444725 |
| ACTG1 | actin gamma 1 | -0.0418441 |
| TMSB10 | thymosin beta 10 | -0.041692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0407992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0349442 |
| RPS6 | ribosomal protein S6 | -0.034574 |
| RPL23 | ribosomal protein L23 | -0.0344393 |
| PTMA | prothymosin, alpha | -0.0307446 |
| FTL | ferritin, light polypeptide | -0.0306538 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294867 |
| RPL35A | ribosomal protein L35a | -0.0292622 |
| EGR1 | early growth response 1 | -0.0292111 |
| RPL19 | ribosomal protein L19 | -0.0282038 |
| RPL37A | ribosomal protein L37a | -0.0279697 |
| FMN1 | formin 1 | -0.0261472 |
| TPM4 | tropomyosin 4 | -0.0250714 |
| RPS14 | ribosomal protein S14 | -0.024918 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0247021 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.02461 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0238283 |
| RPS8 | ribosomal protein S8 | -0.0237412 |
| TLE4 | transducin-like enhancer of split 4 | -0.0234926 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0225739 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0217381 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0213093 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0212546 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0209559 |
| BPTF | bromodomain PHD finger transcription factor | -0.0209449 |
| RPL31 | ribosomal protein L31 | -0.020906 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0206706 |
| RPL9 | ribosomal protein L9 | -0.0206418 |
| MCL1 | myeloid cell leukemia 1 | -0.0206018 |
| RPS19 | ribosomal protein S19 | -0.0202723 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0200163 |
| RPL34 | ribosomal protein L34 | -0.0198255 |
| RPS16 | ribosomal protein S16 | -0.0197448 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0196591 |
| COL1A1 | collagen, type I, alpha 1 | -0.0194295 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191666 |
| EXT1 | exostosin glycosyltransferase 1 | -0.019131 |
| RPS23 | ribosomal protein S23 | -0.0187071 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0186365 |
| RPS29 | ribosomal protein S29 | -0.0181136 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0181083 |
| PCBP2 | poly(rC) binding protein 2 | -0.0179564 |
| CRH | corticotropin releasing hormone | -0.0178188 |
| DTNA | dystrobrevin, alpha | -0.0178081 |
| NREP | neuronal regeneration related protein | -0.0175177 |
| GNAS | GNAS complex locus | -0.017467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0173875 |
| RPL12 | ribosomal protein L12 | -0.0169147 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0166687 |
| RPL36 | ribosomal protein L36 | -0.0164501 |
| MORF4L2 | mortality factor 4 like 2 | -0.0162851 |
| MYO1E | myosin IE | -0.0159591 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0159303 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0159067 |
| FERMT2 | fermitin family member 2 | -0.0158087 |
| FHIT | fragile histidine triad | -0.0157278 |
| GOLGB1 | golgin B1 | -0.0156066 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0155329 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0154782 |
| FBXO11 | F-box protein 11 | -0.015447 |
| ZNF609 | zinc finger protein 609 | -0.0150986 |
| MSI2 | musashi RNA-binding protein 2 | -0.0149119 |
| FN1 | fibronectin 1 | -0.0148701 |
| RPS21 | ribosomal protein S21 | -0.0148685 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0147532 |
| SYT1 | synaptotagmin I | -0.0146276 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0146188 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0145986 |
| RPS12 | ribosomal protein S12 | -0.0145498 |
| SP100 | SP100 nuclear antigen | -0.0144741 |
| CADM2 | cell adhesion molecule 2 | -0.0141945 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0139647 |
| LIMA1 | LIM domain and actin binding 1 | -0.0139167 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0139015 |
| POTEF | POTE ankyrin domain family, member F | -0.0138218 |
| SQSTM1 | sequestosome 1 | -0.0138113 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0137103 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0136234 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0135308 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0134902 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.013444 |
| RPS13 | ribosomal protein S13 | -0.013407 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0133222 |
| S100A9 | S100 calcium binding protein A9 | -0.0132772 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0132111 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.013063 |
| RACK1 | receptor for activated C kinase 1 | -0.0130628 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0130232 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0129913 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.012981 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0128269 |
