| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0889277 |
| STC1 | stanniocalcin 1 | 0.0545956 |
| CALD1 | caldesmon 1 | 0.0408052 |
| ASPH | aspartate beta-hydroxylase | 0.0368494 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0340957 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338106 |
| CANX | calnexin | 0.0323845 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0314663 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0301441 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0274113 |
| CD44 | CD44 molecule (Indian blood group) | 0.027075 |
| SMAD3 | SMAD family member 3 | 0.0266577 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0264866 |
| APP | amyloid beta (A4) precursor protein | 0.0251443 |
| VEGFA | vascular endothelial growth factor A | 0.0251085 |
| LOXL2 | lysyl oxidase-like 2 | 0.0245797 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0244634 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0231358 |
| AHNAK | AHNAK nucleoprotein | 0.0228631 |
| GOLGB1 | golgin B1 | 0.0219884 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0207314 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0206716 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.020418 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0202906 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0201169 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0197722 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0195063 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0187887 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0187719 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0186529 |
| PRELID2 | PRELI domain containing 2 | 0.0184186 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0182609 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0180959 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0180718 |
| ZNF638 | zinc finger protein 638 | 0.0180464 |
| ZNF841 | zinc finger protein 841 | 0.0179501 |
| SETD5 | SET domain containing 5 | 0.0178167 |
| NPC1 | Niemann-Pick disease, type C1 | 0.017749 |
| ANO6 | anoctamin 6 | 0.0177266 |
| VMP1 | vacuole membrane protein 1 | 0.0174696 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0174412 |
| RASA2 | RAS p21 protein activator 2 | 0.017294 |
| YEATS2 | YEATS domain containing 2 | 0.0172001 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0170722 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.016732 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0166717 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0164918 |
| PMM2 | phosphomannomutase 2 | 0.0163933 |
| HMGA2 | high mobility group AT-hook 2 | 0.0163456 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0163069 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0163024 |
| HDAC9 | histone deacetylase 9 | 0.015855 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0158267 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0158096 |
| COL5A1 | collagen, type V, alpha 1 | 0.015688 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0156032 |
| CLTC | clathrin, heavy chain (Hc) | 0.0155407 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0154966 |
| ZNF292 | zinc finger protein 292 | 0.0154202 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0153301 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0152453 |
| SMYD3 | SET and MYND domain containing 3 | 0.0151688 |
| OSMR | oncostatin M receptor | 0.0151319 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.014793 |
| WDR26 | WD repeat domain 26 | 0.0147432 |
| PHF3 | PHD finger protein 3 | 0.0141655 |
| SBF2 | SET binding factor 2 | 0.0141598 |
| CORO1C | coronin, actin binding protein, 1C | 0.0141429 |
| METTL15 | methyltransferase like 15 | 0.0140268 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0139987 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0139853 |
| RASA3 | RAS p21 protein activator 3 | 0.0138647 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0138402 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0137332 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0135903 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0135232 |
| SP3 | Sp3 transcription factor | 0.0135204 |
| VCL | vinculin | 0.0135186 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0134976 |
| MSN | moesin | 0.0134608 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0132896 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.013236 |
| HELZ | helicase with zinc finger | 0.0131933 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0131421 |
| MYOF | myoferlin | 0.0130732 |
| FRMD6 | FERM domain containing 6 | 0.0130311 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0129699 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0128514 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0128277 |
| ATP13A3 | ATPase type 13A3 | 0.0128014 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0126623 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0123985 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0123172 |
| CEP95 | centrosomal protein 95kDa | 0.0123121 |
| GOLGA2 | golgin A2 | 0.0122755 |
| PYGL | phosphorylase, glycogen, liver | 0.0121865 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0120797 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0119887 |
| FOXJ3 | forkhead box J3 | 0.0118791 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0118586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.124709 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0778485 |
| TMSB10 | thymosin beta 10 | -0.0750163 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0713573 |
| VIM | vimentin | -0.0656501 |
| FTL | ferritin, light polypeptide | -0.0540558 |
| FN1 | fibronectin 1 | -0.0441709 |
| NDRG1 | N-myc downstream regulated 1 | -0.0432924 |
| EGR1 | early growth response 1 | -0.0394059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0384518 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.035977 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0287718 |
| GDF15 | growth differentiation factor 15 | -0.0272406 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.026511 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0264994 |
| SQSTM1 | sequestosome 1 | -0.0257091 |
| HLA-B | major histocompatibility complex, class I, B | -0.0248705 |
| PKM | pyruvate kinase, muscle | -0.0245963 |
| MAP1B | microtubule-associated protein 1B | -0.0245292 |
| LOX | lysyl oxidase | -0.0243133 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239145 |
| POTEF | POTE ankyrin domain family, member F | -0.0230684 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0230279 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0225952 |
| RPS8 | ribosomal protein S8 | -0.0216796 |
| GNAS | GNAS complex locus | -0.0214586 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0212238 |
| JUN | jun proto-oncogene | -0.020394 |
| RPS6 | ribosomal protein S6 | -0.0203679 |
| TPM4 | tropomyosin 4 | -0.0194402 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0186926 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0182965 |
| PTMA | prothymosin, alpha | -0.0182936 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0182404 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0182257 |
| LDHA | lactate dehydrogenase A | -0.017611 |
| PFN1 | profilin 1 | -0.0175597 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0171001 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0170015 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0166843 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0165384 |
| RPLP1 | ribosomal protein, large, P1 | -0.0163969 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0160602 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0160322 |
| NLGN1 | neuroligin 1 | -0.0154214 |
| IGF2 | insulin-like growth factor 2 | -0.0150616 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0149438 |
| S100A6 | S100 calcium binding protein A6 | -0.0141907 |
| RPL23 | ribosomal protein L23 | -0.0141651 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0141019 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0140076 |
| LMNA | lamin A/C | -0.013914 |
| HMGA1 | high mobility group AT-hook 1 | -0.0138761 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0136235 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0136135 |
| MT1X | metallothionein 1X | -0.0133514 |
| ADM | adrenomedullin | -0.0131008 |
| TPI1 | triosephosphate isomerase 1 | -0.0130608 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0129899 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0129007 |
| CENPF | centromere protein F, 350/400kDa | -0.0128048 |
| BSG | basigin (Ok blood group) | -0.0126928 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0126465 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0126383 |
| HLA-A | major histocompatibility complex, class I, A | -0.0124986 |
| RPL35A | ribosomal protein L35a | -0.0123579 |
| ACTG1 | actin gamma 1 | -0.0123087 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0122287 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0121764 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0121283 |
| PCBP2 | poly(rC) binding protein 2 | -0.0119845 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0115602 |
| TUBA1B | tubulin, alpha 1b | -0.0114552 |
| FOSL1 | FOS-like antigen 1 | -0.0114232 |
| RPL27A | ribosomal protein L27a | -0.0113797 |
| RPS16 | ribosomal protein S16 | -0.0113566 |
| RPL9 | ribosomal protein L9 | -0.0113218 |
| RPL34 | ribosomal protein L34 | -0.011307 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.011134 |
| RPS13 | ribosomal protein S13 | -0.0111238 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0109502 |
| RPS24 | ribosomal protein S24 | -0.01094 |
| RPS25 | ribosomal protein S25 | -0.0109132 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0108974 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0108771 |
| RPL28 | ribosomal protein L28 | -0.0108219 |
| TAGLN2 | transgelin 2 | -0.0107117 |
| RPS20 | ribosomal protein S20 | -0.010682 |
| CBX3 | chromobox homolog 3 | -0.010665 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.010581 |
| MYADM | myeloid-associated differentiation marker | -0.0104615 |
| RPS23 | ribosomal protein S23 | -0.0104249 |
| SEC61G | Sec61 gamma subunit | -0.0103966 |
| MT2A | metallothionein 2A | -0.0103488 |
| CTSD | cathepsin D | -0.0103091 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0102151 |
| TUBA1C | tubulin, alpha 1c | -0.0101399 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0101042 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0100055 |
| RPS19 | ribosomal protein S19 | -0.00997938 |
