| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.157144 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.132992 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.113718 |
| COL5A1 | collagen, type V, alpha 1 | 0.105778 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.104809 |
| VEGFA | vascular endothelial growth factor A | 0.0810231 |
| HMGA2 | high mobility group AT-hook 2 | 0.0763298 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0722865 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0637512 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0523717 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0517909 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0509233 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0494686 |
| CDH13 | cadherin 13 | 0.0481457 |
| NAV1 | neuron navigator 1 | 0.0447358 |
| PTK2 | protein tyrosine kinase 2 | 0.0411711 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0403274 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0388749 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0388663 |
| PLEC | plectin | 0.0387348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0378453 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370162 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0366886 |
| FAM13A | family with sequence similarity 13, member A | 0.0366783 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0363562 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0359636 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0347153 |
| MYO10 | myosin X | 0.0346634 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0345209 |
| TNS1 | tensin 1 | 0.0344508 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0341612 |
| CD44 | CD44 molecule (Indian blood group) | 0.0335698 |
| VMP1 | vacuole membrane protein 1 | 0.0329315 |
| DTNA | dystrobrevin, alpha | 0.0329223 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0324886 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0322592 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0321552 |
| HPCAL1 | hippocalcin-like 1 | 0.0316849 |
| SMAD3 | SMAD family member 3 | 0.0312715 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0308601 |
| RAI14 | retinoic acid induced 14 | 0.0307479 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0306362 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0304993 |
| LAMB3 | laminin, beta 3 | 0.0304641 |
| LOXL2 | lysyl oxidase-like 2 | 0.0302913 |
| VCL | vinculin | 0.0300589 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0299483 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0295501 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0287389 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0281094 |
| CANX | calnexin | 0.0278113 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0277348 |
| CLMP | CXADR-like membrane protein | 0.0274056 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026973 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0264443 |
| HELZ | helicase with zinc finger | 0.0261378 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.025984 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0256803 |
| AHNAK | AHNAK nucleoprotein | 0.025552 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0252245 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0248487 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0247952 |
| SEPTIN9 | septin 9 | 0.0247951 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0242911 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0239991 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0239395 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0238081 |
| FLNA | filamin A, alpha | 0.0236928 |
| ATP13A3 | ATPase type 13A3 | 0.0236291 |
| SETD5 | SET domain containing 5 | 0.0235801 |
| ANXA2 | annexin A2 | 0.0234282 |
| RUNX1 | runt-related transcription factor 1 | 0.0234187 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0233076 |
| RASA3 | RAS p21 protein activator 3 | 0.0232405 |
| DST | dystonin | 0.0231003 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0228559 |
| APP | amyloid beta (A4) precursor protein | 0.0227934 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.022701 |
| COPA | coatomer protein complex, subunit alpha | 0.0226281 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0225733 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0220936 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0218135 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0217193 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0216756 |
| ACTN1 | actinin, alpha 1 | 0.0216601 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0216376 |
| NAV2 | neuron navigator 2 | 0.0213762 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0212852 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0212402 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0208476 |
| FMN1 | formin 1 | 0.0207013 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0206339 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0205772 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0205723 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0202244 |
| MLPH | melanophilin | 0.0201317 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0200324 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.019716 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.019386 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0193318 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.424548 |
| VIM | vimentin | -0.216886 |
| MT2A | metallothionein 2A | -0.118816 |
| TMSB10 | thymosin beta 10 | -0.109398 |
| PTMA | prothymosin, alpha | -0.0781292 |
| FTL | ferritin, light polypeptide | -0.054375 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0521824 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0457323 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0378757 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0373978 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.037294 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0365213 |
| MT1X | metallothionein 1X | -0.0364728 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0363239 |
| EGR1 | early growth response 1 | -0.0346253 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0340013 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0318179 |
| RPLP1 | ribosomal protein, large, P1 | -0.0315797 |
| RPS19 | ribosomal protein S19 | -0.0300015 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299327 |
| RPL35A | ribosomal protein L35a | -0.0298171 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0285277 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0279515 |
| CCND1 | cyclin D1 | -0.0278177 |
| S100A6 | S100 calcium binding protein A6 | -0.0276196 |
| CENPF | centromere protein F, 350/400kDa | -0.0269855 |
| LDHA | lactate dehydrogenase A | -0.0249102 |
| RPLP0 | ribosomal protein, large, P0 | -0.0244959 |
| SYAP1 | synapse associated protein 1 | -0.0244135 |
| RPL23 | ribosomal protein L23 | -0.0241526 |
| DUSP6 | dual specificity phosphatase 6 | -0.0237378 |
| RPS6 | ribosomal protein S6 | -0.0233697 |
| MAP1B | microtubule-associated protein 1B | -0.0226111 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0223431 |
| PFN1 | profilin 1 | -0.0222762 |
| S100A10 | S100 calcium binding protein A10 | -0.0221973 |
| GNAS | GNAS complex locus | -0.0221149 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0216688 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0204341 |
| RPLP2 | ribosomal protein, large, P2 | -0.0203996 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0199457 |
| NDRG1 | N-myc downstream regulated 1 | -0.0197362 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0194477 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0189833 |
| RPS8 | ribosomal protein S8 | -0.018884 |
| RPL19 | ribosomal protein L19 | -0.0181864 |
| TXNIP | thioredoxin interacting protein | -0.018114 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0180193 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0179495 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0178263 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0176226 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0176113 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0171273 |
| FOSL1 | FOS-like antigen 1 | -0.0170704 |
| RPS24 | ribosomal protein S24 | -0.0168426 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0163929 |
| RPL9 | ribosomal protein L9 | -0.0162558 |
| RPL34 | ribosomal protein L34 | -0.0160607 |
| RPL32 | ribosomal protein L32 | -0.0155147 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0152858 |
| RPS16 | ribosomal protein S16 | -0.014998 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0149548 |
| RPL31 | ribosomal protein L31 | -0.0147138 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.014438 |
| KIF18B | kinesin family member 18B | -0.014433 |
| CCNI | cyclin I | -0.0144308 |
| RPS21 | ribosomal protein S21 | -0.0143566 |
| RPS14 | ribosomal protein S14 | -0.0141108 |
| ACTG1 | actin gamma 1 | -0.0140786 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0139 |
| RPL12 | ribosomal protein L12 | -0.0138857 |
| S100A9 | S100 calcium binding protein A9 | -0.0136678 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0136311 |
| HMGA1 | high mobility group AT-hook 1 | -0.0135683 |
| RPS13 | ribosomal protein S13 | -0.0133786 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0130609 |
| RPL27A | ribosomal protein L27a | -0.0129403 |
| TXNRD1 | thioredoxin reductase 1 | -0.0128998 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0128389 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.012733 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0126528 |
| RPL8 | ribosomal protein L8 | -0.0124611 |
| CDCP1 | CUB domain containing protein 1 | -0.012148 |
| H3-3B | H3.3 histone B | -0.0121138 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0118765 |
| SGO2 | shugoshin 2 | -0.0117232 |
| RTN4 | reticulon 4 | -0.0117182 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0116842 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0116531 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0112939 |
| TPI1 | triosephosphate isomerase 1 | -0.0112929 |
| RPS11 | ribosomal protein S11 | -0.0112475 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0112002 |
| RPS27 | ribosomal protein S27 | -0.0111065 |
| RPL7 | ribosomal protein L7 | -0.0110168 |
| IER3 | immediate early response 3 | -0.0109117 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0108574 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0108505 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0106824 |
| PCBP2 | poly(rC) binding protein 2 | -0.0106186 |
