| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.439448 |
| VEGFA | vascular endothelial growth factor A | 0.249049 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.168204 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0940642 |
| CADM1 | cell adhesion molecule 1 | 0.0744105 |
| ATP13A3 | ATPase type 13A3 | 0.0735226 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0720614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0693041 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0657243 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0626308 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0535058 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0529112 |
| LOXL2 | lysyl oxidase-like 2 | 0.050586 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0461549 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0442808 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0375909 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0369466 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0356864 |
| CALR | calreticulin | 0.0342932 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.033475 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0334551 |
| GOLGA4 | golgin A4 | 0.0323838 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0314507 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0313346 |
| COPA | coatomer protein complex, subunit alpha | 0.0306741 |
| COL5A1 | collagen, type V, alpha 1 | 0.0302322 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0294472 |
| FN1 | fibronectin 1 | 0.0282845 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0279875 |
| VMP1 | vacuole membrane protein 1 | 0.0276237 |
| HIP1 | huntingtin interacting protein 1 | 0.0271822 |
| SETD5 | SET domain containing 5 | 0.026661 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0264174 |
| CCNY | cyclin Y | 0.026237 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0262129 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0260521 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025353 |
| RHOA | ras homolog family member A | 0.0241185 |
| TFG | TRK-fused gene | 0.0239787 |
| ARF4 | ADP-ribosylation factor 4 | 0.0239568 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0237026 |
| RASA2 | RAS p21 protein activator 2 | 0.0235256 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0233082 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0232925 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0229486 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0227132 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0223016 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0222436 |
| PLEC | plectin | 0.0220325 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0215053 |
| MATR3 | matrin 3 | 0.0214821 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0209165 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0208252 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0207268 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0206816 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0203368 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0202754 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0202249 |
| CANX | calnexin | 0.0201141 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0199038 |
| HELZ | helicase with zinc finger | 0.0198468 |
| MRTFA | myocardin related transcription factor A | 0.0196044 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0193602 |
| PGM3 | phosphoglucomutase 3 | 0.0192333 |
| CD109 | CD109 molecule | 0.0192 |
| CLINT1 | clathrin interactor 1 | 0.0191462 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0189955 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.018994 |
| RNF145 | ring finger protein 145 | 0.0186312 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0182699 |
| FOXJ3 | forkhead box J3 | 0.0182123 |
| TNS1 | tensin 1 | 0.0181392 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.018027 |
| PDE8A | phosphodiesterase 8A | 0.0180139 |
| ANXA5 | annexin A5 | 0.0178135 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0177112 |
| TMEM165 | transmembrane protein 165 | 0.0176659 |
| CCNL1 | cyclin L1 | 0.0176588 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0175945 |
| RPN1 | ribophorin I | 0.0175798 |
| CLIC4 | chloride intracellular channel 4 | 0.0175404 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0174852 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0172507 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0171961 |
| CABIN1 | calcineurin binding protein 1 | 0.0170731 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0170354 |
| SUCO | SUN domain containing ossification factor | 0.0169752 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0169412 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0168301 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0167788 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.016611 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0163796 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0163772 |
| USP3 | ubiquitin specific peptidase 3 | 0.0162771 |
| ARRDC3 | arrestin domain containing 3 | 0.0162378 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.016217 |
| TMEM41B | transmembrane protein 41B | 0.0161695 |
| OGA | O-GlcNAcase | 0.0160647 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0159906 |
| VIRMA | vir like m6A methyltransferase associated | 0.015979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266003 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.196975 |
| MT2A | metallothionein 2A | -0.167554 |
| VIM | vimentin | -0.1381 |
| COL1A2 | collagen, type I, alpha 2 | -0.120663 |
| COL1A1 | collagen, type I, alpha 1 | -0.118759 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.11323 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.102965 |
| TMSB10 | thymosin beta 10 | -0.0823687 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0744533 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.069521 |
| ASPH | aspartate beta-hydroxylase | -0.0689733 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0651199 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.057998 |
| MT1X | metallothionein 1X | -0.057479 |
| ACTG1 | actin gamma 1 | -0.056207 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0560361 |
| RPS8 | ribosomal protein S8 | -0.0539427 |
| IL6ST | interleukin 6 signal transducer | -0.0523168 |
| IER3 | immediate early response 3 | -0.050139 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0499208 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0495358 |
| STC1 | stanniocalcin 1 | -0.0488094 |
| HMGA2 | high mobility group AT-hook 2 | -0.0484576 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0482348 |
| FTL | ferritin, light polypeptide | -0.0479085 |
| TPM4 | tropomyosin 4 | -0.0474603 |
| LOX | lysyl oxidase | -0.0439591 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0415458 |
| LDHA | lactate dehydrogenase A | -0.0414071 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0410586 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0398287 |
| RPS2 | ribosomal protein S2 | -0.0390316 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0389686 |
| POSTN | periostin, osteoblast specific factor | -0.0368883 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0366496 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0364208 |
| HLA-B | major histocompatibility complex, class I, B | -0.0357623 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0351332 |
| S100A9 | S100 calcium binding protein A9 | -0.0343816 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0337964 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337878 |
| INHBA | inhibin, beta A | -0.0334741 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0334571 |
| RPL30 | ribosomal protein L30 | -0.033318 |
| NDRG1 | N-myc downstream regulated 1 | -0.0330938 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0329291 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0327449 |
| CD44 | CD44 molecule (Indian blood group) | -0.0323426 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0319189 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0318155 |
| GLIS3 | GLIS family zinc finger 3 | -0.0310216 |
| RPL19 | ribosomal protein L19 | -0.0309244 |
| PTMA | prothymosin, alpha | -0.0306734 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0305036 |
| S100A6 | S100 calcium binding protein A6 | -0.0300426 |
| NRP1 | neuropilin 1 | -0.0299211 |
| RPL8 | ribosomal protein L8 | -0.0292705 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0292477 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0292412 |
| COL3A1 | collagen, type III, alpha 1 | -0.029199 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0286968 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0286451 |
| S100A10 | S100 calcium binding protein A10 | -0.0284039 |
| RPS6 | ribosomal protein S6 | -0.0278304 |
| RPL32 | ribosomal protein L32 | -0.0277789 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02774 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0273345 |
| PKM | pyruvate kinase, muscle | -0.0263096 |
| VCAN | versican | -0.0259208 |
| RPLP2 | ribosomal protein, large, P2 | -0.0258682 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0258113 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0255666 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0254478 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0253142 |
| HAS2 | hyaluronan synthase 2 | -0.0243541 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0241795 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0239518 |
| PGK1 | phosphoglycerate kinase 1 | -0.0239438 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0238944 |
| RPL7 | ribosomal protein L7 | -0.0236181 |
| RPS13 | ribosomal protein S13 | -0.023611 |
| ECE1 | endothelin converting enzyme 1 | -0.0234508 |
| RPL23 | ribosomal protein L23 | -0.0233639 |
| PFN1 | profilin 1 | -0.0230628 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.023035 |
| RPS19 | ribosomal protein S19 | -0.0227322 |
| MX2 | MX dynamin-like GTPase 2 | -0.0226553 |
| RPL28 | ribosomal protein L28 | -0.0223207 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0222736 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0218457 |
| TAPBP | TAP binding protein (tapasin) | -0.0218433 |
| RPL34 | ribosomal protein L34 | -0.021685 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0216205 |
| UBC | ubiquitin C | -0.0215673 |
| RPL36 | ribosomal protein L36 | -0.0214319 |
| DST | dystonin | -0.0213969 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0213849 |
| RPL9 | ribosomal protein L9 | -0.0212458 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0211979 |
