| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.397316 |
| VEGFA | vascular endothelial growth factor A | 0.146007 |
| KRT18 | keratin 18, type I | 0.0993586 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0914975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0690794 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0635168 |
| SMAD3 | SMAD family member 3 | 0.0575437 |
| PTMA | prothymosin, alpha | 0.0544343 |
| KRT8 | keratin 8, type II | 0.0484894 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0483309 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0442586 |
| FRY | furry homolog (Drosophila) | 0.0434376 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0425722 |
| B2M | beta-2-microglobulin | 0.0424722 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0403982 |
| ENO1 | enolase 1, (alpha) | 0.0398472 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0397965 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0383766 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0381261 |
| CALR | calreticulin | 0.0375823 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0373509 |
| MYO18A | myosin XVIIIA | 0.0365153 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0364018 |
| LDHA | lactate dehydrogenase A | 0.0357207 |
| FTL | ferritin, light polypeptide | 0.0345014 |
| CTBP2 | C-terminal binding protein 2 | 0.0337615 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0333869 |
| FAM13A | family with sequence similarity 13, member A | 0.0329146 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0328131 |
| TMEM65 | transmembrane protein 65 | 0.0324806 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.032391 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0322037 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0321718 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0318304 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0318177 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0313454 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0290275 |
| TJP2 | tight junction protein 2 | 0.0281168 |
| ANXA2 | annexin A2 | 0.0278462 |
| JUN | jun proto-oncogene | 0.0275311 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.027443 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0269969 |
| LAMA4 | laminin, alpha 4 | 0.026886 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0267271 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0265143 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0263663 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0259914 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0245988 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0242122 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0240715 |
| KRT20 | keratin 20, type I | 0.0239286 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0235906 |
| TPI1 | triosephosphate isomerase 1 | 0.0232778 |
| WDR45B | WD repeat domain 45B | 0.0232619 |
| LMO7 | LIM domain 7 | 0.0231797 |
| TOP1 | topoisomerase (DNA) I | 0.0231327 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0227598 |
| CA12 | carbonic anhydrase XII | 0.0227252 |
| TNS1 | tensin 1 | 0.0227152 |
| TMSB10 | thymosin beta 10 | 0.0226485 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0225558 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0223925 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0220583 |
| MLPH | melanophilin | 0.0219366 |
| HKDC1 | hexokinase domain containing 1 | 0.0219311 |
| YBX1 | Y box binding protein 1 | 0.0217608 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0216489 |
| GOLGA2 | golgin A2 | 0.0215247 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0214767 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0213621 |
| RHOA | ras homolog family member A | 0.0212177 |
| CCNY | cyclin Y | 0.0210471 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0205071 |
| ARF4 | ADP-ribosylation factor 4 | 0.0201423 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0199786 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0196914 |
| RPS3 | ribosomal protein S3 | 0.0195581 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0191533 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0191304 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0190893 |
| RNF145 | ring finger protein 145 | 0.01908 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0189326 |
| KRT19 | keratin 19, type I | 0.0188924 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188513 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0185631 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0185539 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0183824 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 0.0182862 |
| PDE10A | phosphodiesterase 10A | 0.0182626 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0181496 |
| IRF1 | interferon regulatory factor 1 | 0.0179437 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0178996 |
| RRBP1 | ribosome binding protein 1 | 0.0178454 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0177854 |
| PRSS22 | protease, serine, 22 | 0.0177012 |
| PLEC | plectin | 0.017682 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0176623 |
| SULF2 | sulfatase 2 | 0.0176591 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0175615 |
| SQSTM1 | sequestosome 1 | 0.0174328 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD12 | sterile alpha motif domain containing 12 | -0.100181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0934173 |
| RPS2 | ribosomal protein S2 | -0.084691 |
| TXNRD1 | thioredoxin reductase 1 | -0.0795332 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.073257 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0724583 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0714957 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0700121 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0627764 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0590464 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0574858 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0560655 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.051829 |
| PDZD8 | PDZ domain containing 8 | -0.0513632 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0476872 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0473754 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0457907 |
| PTK2 | protein tyrosine kinase 2 | -0.045553 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.04399 |
| NF1 | neurofibromin 1 | -0.0431638 |
| METTL15 | methyltransferase like 15 | -0.0430765 |
| RBM39 | RNA binding motif protein 39 | -0.0421064 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0420178 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410838 |
| JMJD1C | jumonji domain containing 1C | -0.0397048 |
| FAM135A | family with sequence similarity 135, member A | -0.0392893 |
| SMYD3 | SET and MYND domain containing 3 | -0.0389795 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0382442 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0378616 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0377609 |
| CLTC | clathrin, heavy chain (Hc) | -0.0377511 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0376832 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0367234 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0366708 |
| STK24 | serine/threonine kinase 24 | -0.0360106 |
| RPS12 | ribosomal protein S12 | -0.0356901 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.035358 |
| RPS24 | ribosomal protein S24 | -0.0344135 |
| USP34 | ubiquitin specific peptidase 34 | -0.0341926 |
| ZNF207 | zinc finger protein 207 | -0.034128 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0336091 |
| RPS8 | ribosomal protein S8 | -0.0335764 |
| IL6ST | interleukin 6 signal transducer | -0.0334685 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0330827 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0327768 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0325877 |
| RPL7 | ribosomal protein L7 | -0.0322334 |
| WWC1 | WW and C2 domain containing 1 | -0.0318544 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031295 |
| PKP4 | plakophilin 4 | -0.0312464 |
| RPLP1 | ribosomal protein, large, P1 | -0.0308032 |
| EZR | ezrin | -0.0307188 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0304764 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0299605 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0294873 |
| VCL | vinculin | -0.0291816 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0289585 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0287255 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0283928 |
| RPL27A | ribosomal protein L27a | -0.0281242 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0279165 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0278142 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0277341 |
| TJP1 | tight junction protein 1 | -0.0275504 |
| LATS2 | large tumor suppressor kinase 2 | -0.0272953 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0272792 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0271784 |
| BPTF | bromodomain PHD finger transcription factor | -0.0268761 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.026691 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -0.0266651 |
| RPL21 | ribosomal protein L21 | -0.0264911 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0264676 |
| PLAUR | plasminogen activator, urokinase receptor | -0.026428 |
| ZFR | zinc finger RNA binding protein | -0.0259749 |
| MTAP | methylthioadenosine phosphorylase | -0.0257409 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0257239 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.025707 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0256387 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.025365 |
| RPL19 | ribosomal protein L19 | -0.0252627 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0251861 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0251469 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0250073 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0249694 |
| RPL23 | ribosomal protein L23 | -0.0249149 |
| IPO7 | importin 7 | -0.0244608 |
| TMEM123 | transmembrane protein 123 | -0.0244095 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0244081 |
| NBEAL1 | neurobeachin-like 1 | -0.0243549 |
| STK4 | serine/threonine kinase 4 | -0.0241385 |
| RPL4 | ribosomal protein L4 | -0.0241326 |
| SRPK2 | SRSF protein kinase 2 | -0.023956 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0239057 |
| XPO1 | exportin 1 | -0.0239028 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0239001 |
| ZNF609 | zinc finger protein 609 | -0.0238841 |
| SEPTIN7 | septin 7 | -0.0236917 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.023635 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0236143 |
| GOLT1B | golgi transport 1B | -0.0236059 |
