Methyl aminolevulinate (hydrochloride)_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Methyl aminolevulinate (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FTH1 ferritin, heavy polypeptide 1 0.296406
IGFBP3 insulin-like growth factor binding protein 3 0.148267
ATP13A3 ATPase type 13A3 0.0954231
TRIO trio Rho guanine nucleotide exchange factor 0.0863845
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.082421
AKAP12 A kinase (PRKA) anchor protein 12 0.0816538
VEGFA vascular endothelial growth factor A 0.0679897
CALR calreticulin 0.0565723
BHLHE40 basic helix-loop-helix family, member e40 0.0523189
MYH9 myosin, heavy chain 9, non-muscle 0.0520826
B2M beta-2-microglobulin 0.0475119
FLNB filamin B, beta 0.0458369
CXCL8 chemokine (C-X-C motif) ligand 8 0.0435835
ARF4 ADP-ribosylation factor 4 0.0397898
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0390734
TMSB4X thymosin beta 4, X-linked 0.0353479
ADM adrenomedullin 0.0325944
ELL2 elongation factor, RNA polymerase II, 2 0.0307863
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0295644
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0291792
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0285876
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0285416
UBA6 ubiquitin-like modifier activating enzyme 6 0.0280183
FN1 fibronectin 1 0.0271815
HLA-C major histocompatibility complex, class I, C 0.0267404
NUP58 nucleoporin 58 0.0266711
PLIN2 perilipin 2 0.0257061
CORO1C coronin, actin binding protein, 1C 0.0256857
SOD2 superoxide dismutase 2, mitochondrial 0.0245316
DENND5A DENN/MADD domain containing 5A 0.0241618
RHOA ras homolog family member A 0.0240933
CCNL1 cyclin L1 0.0236847
RAD23B RAD23 homolog B (S. cerevisiae) 0.023447
USP3 ubiquitin specific peptidase 3 0.0231568
JUN jun proto-oncogene 0.0228459
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.0227103
ANKRD10 ankyrin repeat domain 10 0.0222271
MMP12 matrix metallopeptidase 12 0.0216714
ZNF841 zinc finger protein 841 0.0215611
TFG TRK-fused gene 0.0215184
BTG1 B-cell translocation gene 1, anti-proliferative 0.0212883
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.021013
ANXA2 annexin A2 0.0209166
OGA O-GlcNAcase 0.020865
BZW1 basic leucine zipper and W2 domains 1 0.0208163
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.0207296
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.020715
PODXL podocalyxin-like 0.020278
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0200234
ANXA5 annexin A5 0.019764
ZEB2 zinc finger E-box binding homeobox 2 0.0196943
COL7A1 collagen, type VII, alpha 1 0.0196289
TGFB2 transforming growth factor, beta 2 0.0195707
ADAM9 ADAM metallopeptidase domain 9 0.0192707
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0183805
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0183104
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.0182532
CEP250 centrosomal protein 250kDa 0.0181527
TRIM33 tripartite motif containing 33 0.0180307
COPA coatomer protein complex, subunit alpha 0.0179352
RPN1 ribophorin I 0.0176675
CRY1 cryptochrome circadian clock 1 0.01762
DRAM1 DNA-damage regulated autophagy modulator 1 0.0175607
RNF145 ring finger protein 145 0.0173362
RAB8B RAB8B, member RAS oncogene family 0.0169629
RSL1D1 ribosomal L1 domain containing 1 0.0168487
TSC22D2 TSC22 domain family, member 2 0.016847
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0168038
ARGLU1 arginine and glutamate rich 1 0.0166174
PDIA3 protein disulfide isomerase family A, member 3 0.0162002
MARCHF6 membrane associated ring-CH-type finger 6 0.0161738
COL5A1 collagen, type V, alpha 1 0.016155
SMAD3 SMAD family member 3 0.016124
CD47 CD47 molecule 0.0161098
CTNNBL1 catenin, beta like 1 0.0160755
CLDND1 claudin domain containing 1 0.0159502
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0158535
LOXL2 lysyl oxidase-like 2 0.0158473
INSIG2 insulin induced gene 2 0.0156153
CXCL3 chemokine (C-X-C motif) ligand 3 0.0155089
TEX10 testis expressed 10 0.0153859
BMPER BMP binding endothelial regulator 0.0153578
UBAP2L ubiquitin associated protein 2-like 0.015352
AHNAK AHNAK nucleoprotein 0.0153137
TMEM41B transmembrane protein 41B 0.0152651
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0150931
KDM6A lysine (K)-specific demethylase 6A 0.0148988
FAM162A family with sequence similarity 162, member A 0.0148188
MATR3 matrin 3 0.0147596
NCOA3 nuclear receptor coactivator 3 0.014678
HILPDA hypoxia inducible lipid droplet-associated 0.0146749
SLC12A8 solute carrier family 12, member 8 0.0145524
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0144455
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0144176
ANKRD36 ankyrin repeat domain 36 0.0143351
XPO6 exportin 6 0.0143058
SPRED2 sprouty-related, EVH1 domain containing 2 0.0142975
POU2F1 POU class 2 homeobox 1 0.0141584
CPAP centrosome assembly and centriole elongation protein 0.0141452
NPEPPS aminopeptidase puromycin sensitive 0.0141232

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.145121
HLA-B major histocompatibility complex, class I, B -0.141947
NALF1 NALCN channel auxiliary factor 1 -0.101529
ASPH aspartate beta-hydroxylase -0.10077
FTL ferritin, light polypeptide -0.0911844
MT2A metallothionein 2A -0.0849903
TXNRD1 thioredoxin reductase 1 -0.0790964
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.077886
ZNF432 zinc finger protein 432 -0.0658746
NDRG1 N-myc downstream regulated 1 -0.0635011
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0577556
RPS6 ribosomal protein S6 -0.0555312
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0545098
EXT1 exostosin glycosyltransferase 1 -0.0534172
FNDC3B fibronectin type III domain containing 3B -0.0523828
DIAPH3 diaphanous-related formin 3 -0.0496144
IL6ST interleukin 6 signal transducer -0.0494934
SQSTM1 sequestosome 1 -0.0493831
ACTG1 actin gamma 1 -0.049265
HEG1 heart development protein with EGF-like domains 1 -0.0491425
MT1X metallothionein 1X -0.0475244
ZBTB20 zinc finger and BTB domain containing 20 -0.0464297
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0463502
LDHA lactate dehydrogenase A -0.0453988
TPT1 tumor protein, translationally-controlled 1 -0.0438973
PKM pyruvate kinase, muscle -0.0424529
DPYD dihydropyrimidine dehydrogenase -0.0405682
SMC4 structural maintenance of chromosomes 4 -0.0400212
CCND1 cyclin D1 -0.038375
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0381875
RPS8 ribosomal protein S8 -0.0376349
CENPF centromere protein F, 350/400kDa -0.0363545
GOLGB1 golgin B1 -0.0360399
KTN1 kinectin 1 (kinesin receptor) -0.0352542
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0349823
NIPBL Nipped-B homolog (Drosophila) -0.0349175
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0345474
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0344018
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0342799
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0341087
C6ORF62 chromosome 6 open reading frame 62 -0.0332535
RHOBTB3 Rho-related BTB domain containing 3 -0.0328218
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0327902
RPLP2 ribosomal protein, large, P2 -0.0326521
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0325529
MAP1B microtubule-associated protein 1B -0.0322145
SMYD3 SET and MYND domain containing 3 -0.0316937
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0310792
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0303665
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0295614
ANKRD12 ankyrin repeat domain 12 -0.0290587
FOXP1 forkhead box P1 -0.0289389
PLSCR1 phospholipid scramblase 1 -0.0288526
CLTC clathrin, heavy chain (Hc) -0.0283535
STAT1 signal transducer and activator of transcription 1, 91kDa -0.028305
DST dystonin -0.028252
AFAP1 actin filament associated protein 1 -0.0281841
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0281157
PTPRG protein tyrosine phosphatase, receptor type, G -0.0280188
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0279925
TENM3 teneurin transmembrane protein 3 -0.0279512
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0278547
SAMD12 sterile alpha motif domain containing 12 -0.0277988
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.0277832
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0276433
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0275291
BBX bobby sox homolog (Drosophila) -0.0275238
WWOX WW domain containing oxidoreductase -0.0274668
RPS2 ribosomal protein S2 -0.0270639
DEK DEK proto-oncogene -0.0268383
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0268108
RPL27A ribosomal protein L27a -0.0263716
RPLP1 ribosomal protein, large, P1 -0.0261807
PFN1 profilin 1 -0.0260727
OSMR oncostatin M receptor -0.0256892
HMGB1 high mobility group box 1 -0.025665
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0252266
STAU1 staufen double-stranded RNA binding protein 1 -0.0251746
ERBIN erbb2 interacting protein -0.0250515
ZNFX1 zinc finger, NFX1-type containing 1 -0.0248773
POTEF POTE ankyrin domain family, member F -0.0244429
VIM vimentin -0.0243771
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0243448
H1-4 H1.4 linker histone, cluster member -0.0241914
HMGA1 high mobility group AT-hook 1 -0.0241153
HLA-E major histocompatibility complex, class I, E -0.023971
TUBA1B tubulin, alpha 1b -0.0238395
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0238062
RPL12 ribosomal protein L12 -0.0237474
PDE4D phosphodiesterase 4D, cAMP-specific -0.0234906
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0234707
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0234156
DLG1 discs, large homolog 1 (Drosophila) -0.0232544
RPL30 ribosomal protein L30 -0.0231654
E2F3 E2F transcription factor 3 -0.0229081
SET SET nuclear proto-oncogene -0.0226087
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0225468
TMSB10 thymosin beta 10 -0.0224996
ADNP activity-dependent neuroprotector homeobox -0.0224549
TAS2R14 taste receptor, type 2, member 14 -0.0224253