| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0926081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0880584 |
| INTS6 | integrator complex subunit 6 | 0.0770731 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.074262 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0725142 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0723648 |
| DSPP | dentin sialophosphoprotein | 0.0719519 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0707678 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0657905 |
| MYO1E | myosin IE | 0.0651599 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0600097 |
| EZR | ezrin | 0.0581725 |
| PDLIM5 | PDZ and LIM domain 5 | 0.057959 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0522641 |
| RPL3 | ribosomal protein L3 | 0.0489593 |
| FBXO11 | F-box protein 11 | 0.0489178 |
| FRMD5 | FERM domain containing 5 | 0.04632 |
| CTBP2 | C-terminal binding protein 2 | 0.046015 |
| VEGFA | vascular endothelial growth factor A | 0.0456925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0438535 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0434518 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.043248 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0429602 |
| RCOR1 | REST corepressor 1 | 0.0427728 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0422541 |
| POTEF | POTE ankyrin domain family, member F | 0.0403827 |
| MYO5B | myosin VB | 0.0402205 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0393245 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0388287 |
| RPS18 | ribosomal protein S18 | 0.0381176 |
| OXSR1 | oxidative stress responsive 1 | 0.036202 |
| ANXA2 | annexin A2 | 0.035719 |
| VMP1 | vacuole membrane protein 1 | 0.0355797 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0342723 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0340954 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0321387 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.031927 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0315694 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0313983 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0313431 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0308766 |
| BRD2 | bromodomain containing 2 | 0.0308724 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.030682 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0306698 |
| DIAPH1 | diaphanous-related formin 1 | 0.0303141 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0302101 |
| UBAP2 | ubiquitin associated protein 2 | 0.0296365 |
| CALB1 | calbindin 1, 28kDa | 0.029047 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0287007 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0282411 |
| RHOA | ras homolog family member A | 0.0279795 |
| MCU | mitochondrial calcium uniporter | 0.0275495 |
| USP53 | ubiquitin specific peptidase 53 | 0.0275172 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0272406 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0271657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0262692 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.026255 |
| NABP1 | nucleic acid binding protein 1 | 0.0262114 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0257326 |
| NRDC | nardilysin convertase | 0.0254615 |
| KRT18 | keratin 18, type I | 0.0254584 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0254465 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0253405 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0252297 |
| LRRC23 | leucine rich repeat containing 23 | 0.0249767 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0249056 |
| TJP1 | tight junction protein 1 | 0.0248934 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0247636 |
| ADIPOR2 | adiponectin receptor 2 | 0.0246084 |
| CLIC5 | chloride intracellular channel 5 | 0.0244893 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0243253 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0242376 |
| SVIL | supervillin | 0.0239111 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0236936 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0234193 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233644 |
| SP100 | SP100 nuclear antigen | 0.0230182 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0227814 |
| PGM3 | phosphoglucomutase 3 | 0.0226602 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0220375 |
| ARF4 | ADP-ribosylation factor 4 | 0.0220136 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219545 |
| NPSR1 | neuropeptide S receptor 1 | 0.0218182 |
| ANKRD13C | ankyrin repeat domain 13C | 0.0217134 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0216763 |
| ZNF83 | zinc finger protein 83 | 0.0215785 |
| RPL21 | ribosomal protein L21 | 0.0214701 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.021189 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.021069 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209649 |
| SEPTIN9 | septin 9 | 0.0208586 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0208086 |
| FNIP1 | folliculin interacting protein 1 | 0.0207143 |
| FOXO3 | forkhead box O3 | 0.0202944 |
| FLNB | filamin B, beta | 0.0201642 |
| KIAA1671 | KIAA1671 | 0.0198794 |
| INO80 | INO80 complex subunit | 0.0198254 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0197822 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0197599 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0197529 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.158471 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.151905 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.139689 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114391 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.109321 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.105119 |
| TXNRD1 | thioredoxin reductase 1 | -0.0901997 |
| RPLP0 | ribosomal protein, large, P0 | -0.0874057 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0676029 |
| TMSB10 | thymosin beta 10 | -0.0671221 |
| RPS8 | ribosomal protein S8 | -0.0601322 |
| RPS24 | ribosomal protein S24 | -0.0596786 |
| RPL13A | ribosomal protein L13a | -0.0593247 |
| RPL34 | ribosomal protein L34 | -0.0589304 |
| PLAC8 | placenta-specific 8 | -0.0587352 |
| RPL4 | ribosomal protein L4 | -0.0578735 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0574199 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0560332 |
| RPL35A | ribosomal protein L35a | -0.0556122 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0506638 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0494518 |
| RPL27A | ribosomal protein L27a | -0.0452931 |
| PCDHB16 | protocadherin beta 16 | -0.0443469 |
| RPS21 | ribosomal protein S21 | -0.0442069 |
| RPLP2 | ribosomal protein, large, P2 | -0.0441757 |
| PKP2 | plakophilin 2 | -0.0439348 |
| PRSS3 | protease, serine, 3 | -0.0438751 |
| PRELID2 | PRELI domain containing 2 | -0.0436295 |
| RPS19 | ribosomal protein S19 | -0.0434425 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0429675 |
| RPL23 | ribosomal protein L23 | -0.0427976 |
| SHROOM3 | shroom family member 3 | -0.0424746 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0424413 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0408113 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0403609 |
| ACTG1 | actin gamma 1 | -0.0403361 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | -0.040301 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.038936 |
| RPL12 | ribosomal protein L12 | -0.0383199 |
| FOXO1 | forkhead box O1 | -0.0381722 |
| TSPAN8 | tetraspanin 8 | -0.0377156 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0373424 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0373416 |
| FOXP1 | forkhead box P1 | -0.0367086 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0363184 |
| RPL9 | ribosomal protein L9 | -0.036037 |
| RPS27A | ribosomal protein S27a | -0.035407 |
| NDRG1 | N-myc downstream regulated 1 | -0.0346202 |
| AGR2 | anterior gradient 2 | -0.0341412 |
| IER3 | immediate early response 3 | -0.0340201 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0337883 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0337009 |
| ABHD17C | abhydrolase domain containing 17C | -0.0332673 |
| ZNF292 | zinc finger protein 292 | -0.0327083 |
| RPL30 | ribosomal protein L30 | -0.0326491 |
| PTMA | prothymosin, alpha | -0.0325409 |
| CXADR | coxsackie virus and adenovirus receptor | -0.032522 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0324796 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0318269 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312049 |
| RPS16 | ribosomal protein S16 | -0.0309323 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0304595 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0302094 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0300648 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0299023 |
| PGK1 | phosphoglycerate kinase 1 | -0.0298699 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0297471 |
| RPL38 | ribosomal protein L38 | -0.0296988 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0295344 |
| RPS29 | ribosomal protein S29 | -0.0294498 |
| RNF213 | ring finger protein 213 | -0.029118 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0290466 |
| ETV6 | ets variant 6 | -0.0289027 |
| RRBP1 | ribosome binding protein 1 | -0.0287931 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0287295 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0280858 |
| RPS20 | ribosomal protein S20 | -0.0278244 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0275226 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0274742 |
| CLINT1 | clathrin interactor 1 | -0.0274263 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0272976 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0272676 |
| RPL32 | ribosomal protein L32 | -0.0272075 |
| TRIM56 | tripartite motif containing 56 | -0.026688 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0266148 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0265295 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0264955 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0262632 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0262302 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0261106 |
| TMEM45B | transmembrane protein 45B | -0.0260912 |
| VDAC1 | voltage-dependent anion channel 1 | -0.025447 |
| YBX3 | Y box binding protein 3 | -0.0251727 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0250974 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0249346 |
| CCPG1 | cell cycle progression 1 | -0.0246867 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0244448 |
| HMGB1 | high mobility group box 1 | -0.0243715 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0243145 |
| GDF15 | growth differentiation factor 15 | -0.0241287 |
