| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.188168 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.180104 |
| VEGFA | vascular endothelial growth factor A | 0.126561 |
| GRB10 | growth factor receptor-bound protein 10 | 0.100553 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0832059 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.070731 |
| ATP13A3 | ATPase type 13A3 | 0.0679919 |
| VMP1 | vacuole membrane protein 1 | 0.064657 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0640838 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.063078 |
| NGLY1 | N-glycanase 1 | 0.0618211 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0576461 |
| RNF145 | ring finger protein 145 | 0.0572518 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0548136 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.053311 |
| COPA | coatomer protein complex, subunit alpha | 0.0522761 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0515313 |
| FAM20C | family with sequence similarity 20, member C | 0.0512013 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0506682 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0501151 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0497604 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0496204 |
| SIK3 | SIK family kinase 3 | 0.0491676 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0484565 |
| SETD5 | SET domain containing 5 | 0.0479939 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0476138 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0475299 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0470913 |
| MEF2A | myocyte enhancer factor 2A | 0.0463447 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0457105 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0455845 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0445363 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0438871 |
| TMSB10 | thymosin beta 10 | 0.0434735 |
| VIM | vimentin | 0.0433056 |
| ANXA2 | annexin A2 | 0.0425308 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0399494 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0392427 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0389869 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0382484 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0380347 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0375996 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0360136 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0358316 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0356619 |
| CALR | calreticulin | 0.0353783 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0353571 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0353045 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0349224 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0348925 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0339246 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0332188 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0331642 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0327091 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0326935 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0319704 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0319271 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0317485 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0315804 |
| AAK1 | AP2 associated kinase 1 | 0.0315463 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0314586 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312818 |
| OXSR1 | oxidative stress responsive 1 | 0.0311204 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0310651 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.030883 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0308537 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0305566 |
| USP3 | ubiquitin specific peptidase 3 | 0.0300964 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0300733 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0300345 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0299699 |
| GLCCI1 | glucocorticoid induced 1 | 0.0297241 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0296957 |
| ABI1 | abl-interactor 1 | 0.0293933 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0292752 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.029139 |
| RUNX2 | runt-related transcription factor 2 | 0.0288229 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0287097 |
| YTHDC1 | YTH domain containing 1 | 0.0287025 |
| MATR3 | matrin 3 | 0.0284986 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0282355 |
| YME1L1 | YME1-like 1 ATPase | 0.0276434 |
| AOPEP | aminopeptidase O (putative) | 0.0272407 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0272104 |
| POU2F1 | POU class 2 homeobox 1 | 0.0271966 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0270185 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0269215 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0268458 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0264026 |
| SMAD4 | SMAD family member 4 | 0.0259494 |
| MLPH | melanophilin | 0.0259219 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0256543 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0253899 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0250576 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0248648 |
| ADD3 | adducin 3 (gamma) | 0.024742 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0246828 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0246699 |
| OGA | O-GlcNAcase | 0.0245513 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0244876 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195735 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.135 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134062 |
| EFNA5 | ephrin-A5 | -0.123886 |
| SMAD3 | SMAD family member 3 | -0.0959371 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0941703 |
| NDRG1 | N-myc downstream regulated 1 | -0.0891498 |
| MT2A | metallothionein 2A | -0.0871421 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0785116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0776672 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0775901 |
| ASPH | aspartate beta-hydroxylase | -0.075636 |
| NRG1 | neuregulin 1 | -0.0748112 |
| RPS2 | ribosomal protein S2 | -0.0713345 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0713261 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0706726 |
| USP34 | ubiquitin specific peptidase 34 | -0.0656422 |
| CDCP1 | CUB domain containing protein 1 | -0.0656326 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0639772 |
| RAD51B | RAD51 paralog B | -0.0632136 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0631109 |
| CD44 | CD44 molecule (Indian blood group) | -0.0578442 |
| ATXN1 | ataxin 1 | -0.0571864 |
| DPYD | dihydropyrimidine dehydrogenase | -0.054724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0544494 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0536001 |
| CDH13 | cadherin 13 | -0.0533433 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0512024 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0489191 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0482251 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0473401 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0462628 |
| TXNRD1 | thioredoxin reductase 1 | -0.0458391 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0445361 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0442984 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0437291 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0436572 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0434577 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0433297 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0430362 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0391932 |
| YBX3 | Y box binding protein 3 | -0.0384371 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0380841 |
| GPC6 | glypican 6 | -0.038003 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0377715 |
| ECE1 | endothelin converting enzyme 1 | -0.037327 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0371052 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0363548 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0362859 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0354531 |
| IFI44L | interferon-induced protein 44-like | -0.0351497 |
| SLFN5 | schlafen family member 5 | -0.0346024 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339894 |
| MCL1 | myeloid cell leukemia 1 | -0.033637 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0334972 |
| MTSS1 | metastasis suppressor 1 | -0.0331485 |
| DST | dystonin | -0.0330788 |
| PKM | pyruvate kinase, muscle | -0.0325132 |
| MYO10 | myosin X | -0.0324929 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.032461 |
| RPS12 | ribosomal protein S12 | -0.0322011 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0318847 |
| CDK6 | cyclin-dependent kinase 6 | -0.0318772 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0317097 |
| IL6ST | interleukin 6 signal transducer | -0.0313542 |
| ETV6 | ets variant 6 | -0.03094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0303874 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0303859 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0303669 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.030324 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303131 |
| IFI44 | interferon-induced protein 44 | -0.0301174 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0300119 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0296102 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295687 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0295655 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0295469 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0294869 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0292231 |
| RIGI | RNA sensor RIG-I | -0.0291398 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0288694 |
| SYT1 | synaptotagmin I | -0.0287585 |
| RPS8 | ribosomal protein S8 | -0.0284958 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0282544 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0280816 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0280078 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0280009 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0279302 |
| KIAA1328 | KIAA1328 | -0.0277531 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0275585 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0275494 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.027545 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0275357 |
| ZNF638 | zinc finger protein 638 | -0.0271394 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0270253 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0269731 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0269392 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0268025 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0267915 |
| RPL32 | ribosomal protein L32 | -0.0264683 |
