| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.144066 |
| INHBA | inhibin, beta A | 0.116343 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.111338 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.106544 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0918906 |
| RTN4 | reticulon 4 | 0.0775329 |
| EGFR | epidermal growth factor receptor | 0.0716244 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0705647 |
| COL6A3 | collagen, type VI, alpha 3 | 0.070471 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0667486 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0658817 |
| FN1 | fibronectin 1 | 0.0648141 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0595548 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.056609 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0560922 |
| CLTC | clathrin, heavy chain (Hc) | 0.0559662 |
| TXNIP | thioredoxin interacting protein | 0.0549857 |
| CD44 | CD44 molecule (Indian blood group) | 0.054955 |
| STC1 | stanniocalcin 1 | 0.053442 |
| S100A9 | S100 calcium binding protein A9 | 0.0514614 |
| DSCAM | Down syndrome cell adhesion molecule | 0.051418 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0514125 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0513598 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0513536 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0495228 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0489304 |
| HMGA2 | high mobility group AT-hook 2 | 0.0485938 |
| RBM25 | RNA binding motif protein 25 | 0.0479321 |
| RUNX1 | runt-related transcription factor 1 | 0.0473347 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0467961 |
| FMNL2 | formin-like 2 | 0.0467226 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0459444 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0459033 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.045343 |
| DST | dystonin | 0.0452984 |
| FAM13A | family with sequence similarity 13, member A | 0.0451024 |
| PEG10 | paternally expressed 10 | 0.0447581 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0441411 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0436997 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0436686 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0434856 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0422891 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0422753 |
| ANXA1 | annexin A1 | 0.0422535 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0421268 |
| LDHA | lactate dehydrogenase A | 0.0410608 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0406571 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0400087 |
| SUCO | SUN domain containing ossification factor | 0.0399954 |
| RPS6 | ribosomal protein S6 | 0.0398627 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0396878 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0395768 |
| TPR | translocated promoter region, nuclear basket protein | 0.0393443 |
| B2M | beta-2-microglobulin | 0.0389262 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0388593 |
| COL1A2 | collagen, type I, alpha 2 | 0.0383688 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.038252 |
| AHI1 | Abelson helper integration site 1 | 0.0379252 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0378786 |
| RANBP2 | RAN binding protein 2 | 0.0376454 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0375884 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0375098 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0375062 |
| AHR | aryl hydrocarbon receptor | 0.0372782 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0370116 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0369702 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0368901 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0364175 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0363792 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0363548 |
| PKM | pyruvate kinase, muscle | 0.0362727 |
| MCL1 | myeloid cell leukemia 1 | 0.035824 |
| OXR1 | oxidation resistance 1 | 0.0357509 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0353936 |
| NUMB | numb homolog (Drosophila) | 0.0353773 |
| PHF3 | PHD finger protein 3 | 0.0352282 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0348984 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0346873 |
| VIM | vimentin | 0.0346042 |
| MYO9A | myosin IXA | 0.0340844 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0339807 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0338504 |
| TMEM165 | transmembrane protein 165 | 0.033845 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0336868 |
| PDS5B | PDS5 cohesin associated factor B | 0.0334364 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0331733 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0331056 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0326343 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0324975 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0323018 |
| VMP1 | vacuole membrane protein 1 | 0.0322469 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0320475 |
| RPS8 | ribosomal protein S8 | 0.0319276 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0316534 |
| TES | testin LIM domain protein | 0.0311298 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0308184 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0307507 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0304209 |
| ANXA2 | annexin A2 | 0.0302217 |
| GSE1 | Gse1 coiled-coil protein | 0.030054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.158746 |
| IGF2 | insulin-like growth factor 2 | -0.123157 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.114058 |
| MUC16 | mucin 16, cell surface associated | -0.101614 |
| MT2A | metallothionein 2A | -0.0905878 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0904402 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0812411 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0764429 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.07578 |
| MYOF | myoferlin | -0.0733394 |
| LAMC2 | laminin, gamma 2 | -0.0704096 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0696343 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0690241 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0688501 |
| KYNU | kynureninase | -0.0677545 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0651971 |
| FLNB | filamin B, beta | -0.0650238 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0635385 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0617414 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0614402 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0586145 |
| SMAD3 | SMAD family member 3 | -0.0573503 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.057057 |
| ANKRD36C | ankyrin repeat domain 36C | -0.056861 |
| RBM47 | RNA binding motif protein 47 | -0.0540773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0540548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0535742 |
| LMO7 | LIM domain 7 | -0.0532864 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0529392 |
| EFNA5 | ephrin-A5 | -0.0521862 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0520283 |
| SVIL | supervillin | -0.0506241 |
| ATOSA | atos homolog A | -0.0504876 |
| SQSTM1 | sequestosome 1 | -0.0491029 |
| RNF213 | ring finger protein 213 | -0.0488652 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0474768 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0461003 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.04536 |
| ABHD17C | abhydrolase domain containing 17C | -0.0450047 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0445644 |
| FOSL2 | FOS-like antigen 2 | -0.0444771 |
| LOXL2 | lysyl oxidase-like 2 | -0.0442475 |
| EZR | ezrin | -0.0437329 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.043329 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0433212 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0432016 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0422993 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0421621 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0421337 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | -0.041985 |
| KIF13B | kinesin family member 13B | -0.0411738 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0408936 |
| ERBIN | erbb2 interacting protein | -0.0406368 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0402868 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0402675 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0399189 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0398745 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.039622 |
| EXOC6B | exocyst complex component 6B | -0.0394417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0387365 |
| FTL | ferritin, light polypeptide | -0.0379753 |
| ZNF207 | zinc finger protein 207 | -0.0375846 |
| CCND1 | cyclin D1 | -0.0375403 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0374301 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0372958 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0371708 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0371332 |
| RPS16 | ribosomal protein S16 | -0.0369295 |
| ZNF638 | zinc finger protein 638 | -0.0365246 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.036069 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0352906 |
| MEF2A | myocyte enhancer factor 2A | -0.0350873 |
| INTS6 | integrator complex subunit 6 | -0.034864 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0344898 |
| ATP13A3 | ATPase type 13A3 | -0.0342458 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0341641 |
| LMNA | lamin A/C | -0.0336793 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0333914 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0326785 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0326603 |
| C1D | C1D nuclear receptor corepressor | -0.0325341 |
| SNX9 | sorting nexin 9 | -0.0324218 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0316192 |
| STK4 | serine/threonine kinase 4 | -0.0315588 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0312325 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0309965 |
| KLHL24 | kelch-like family member 24 | -0.0309007 |
| TJP1 | tight junction protein 1 | -0.030895 |
| PML | promyelocytic leukemia | -0.0306722 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0306661 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0305994 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0305128 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0304684 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.030371 |
| DENND1A | DENN/MADD domain containing 1A | -0.0300585 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0297016 |
| CDK17 | cyclin-dependent kinase 17 | -0.0296783 |
| MYO1E | myosin IE | -0.0295326 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0294672 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0293499 |
