| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.307727 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.134915 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0841271 |
| COPA | coatomer protein complex, subunit alpha | 0.081691 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0573443 |
| VMP1 | vacuole membrane protein 1 | 0.0560378 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0526955 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.052345 |
| CCNL1 | cyclin L1 | 0.0489329 |
| KRT18 | keratin 18, type I | 0.0487324 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.045952 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.045282 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0406746 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0405636 |
| SETD5 | SET domain containing 5 | 0.0402078 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0399534 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0396498 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0396383 |
| CEP250 | centrosomal protein 250kDa | 0.0387614 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0383887 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0382291 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0379195 |
| SMAD3 | SMAD family member 3 | 0.0372722 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0371047 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0367918 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0360437 |
| TPM3 | tropomyosin 3 | 0.0358955 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0351299 |
| PNN | pinin, desmosome associated protein | 0.0351097 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0350861 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0343227 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0336942 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.033246 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0328902 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0327605 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0325528 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0325305 |
| GON4L | gon-4-like (C. elegans) | 0.0323148 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0320889 |
| PTMS | parathymosin | 0.0320168 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031831 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0315956 |
| CDC27 | cell division cycle 27 | 0.031245 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0309277 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0308889 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0308707 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0305384 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.03007 |
| ANXA5 | annexin A5 | 0.0298659 |
| KIAA1328 | KIAA1328 | 0.0295974 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0294323 |
| TPM2 | tropomyosin 2 (beta) | 0.0294177 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0290486 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.028824 |
| ARF4 | ADP-ribosylation factor 4 | 0.0284909 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0280088 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.027687 |
| TXNRD1 | thioredoxin reductase 1 | 0.0275397 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0274541 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0273711 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0270931 |
| SPAG5 | sperm associated antigen 5 | 0.0269616 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0269181 |
| CASC3 | cancer susceptibility candidate 3 | 0.0266862 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0265784 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.026352 |
| PLS3 | plastin 3 | 0.0263057 |
| WASF2 | WAS protein family, member 2 | 0.0260131 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0259636 |
| COG5 | component of oligomeric golgi complex 5 | 0.0259035 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0253845 |
| RBMX | RNA binding motif protein, X-linked | 0.0253627 |
| ATL2 | atlastin GTPase 2 | 0.0253325 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.024961 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0249381 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0248701 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0248189 |
| PTEN | phosphatase and tensin homolog | 0.0246083 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.024568 |
| ATXN2 | ataxin 2 | 0.0244679 |
| FDPS | farnesyl diphosphate synthase | 0.0241975 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239961 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0237627 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0236886 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0236247 |
| GLG1 | golgi glycoprotein 1 | 0.0235779 |
| RNF145 | ring finger protein 145 | 0.0233776 |
| NUP58 | nucleoporin 58 | 0.0232854 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0232789 |
| PGK1 | phosphoglycerate kinase 1 | 0.0231805 |
| RHOA | ras homolog family member A | 0.0230181 |
| ZYX | zyxin | 0.0229721 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0229155 |
| CLIC4 | chloride intracellular channel 4 | 0.0228869 |
| MSI2 | musashi RNA-binding protein 2 | 0.0226629 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0224764 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0224261 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0223451 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.0223396 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0223344 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.213718 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181488 |
| YBX3 | Y box binding protein 3 | -0.100598 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0985502 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0719969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0695208 |
| RPL38 | ribosomal protein L38 | -0.0692208 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0673612 |
| TMSB10 | thymosin beta 10 | -0.058357 |
| ACTG1 | actin gamma 1 | -0.0573951 |
| RPS2 | ribosomal protein S2 | -0.0573354 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0569647 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0568942 |
| RPS8 | ribosomal protein S8 | -0.0561245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0554007 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0538094 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0530135 |
| RPL37 | ribosomal protein L37 | -0.0513909 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0495179 |
| CCND2 | cyclin D2 | -0.048642 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.048447 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0480417 |
| RPL12 | ribosomal protein L12 | -0.047567 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0469003 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0446174 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0440561 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0432302 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0429085 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0426546 |
| RBM39 | RNA binding motif protein 39 | -0.0417867 |
| RPL19 | ribosomal protein L19 | -0.0412754 |
| RPLP0 | ribosomal protein, large, P0 | -0.0412203 |
| NABP1 | nucleic acid binding protein 1 | -0.0400268 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0397412 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0377954 |
| RPS29 | ribosomal protein S29 | -0.0377851 |
| RPS21 | ribosomal protein S21 | -0.0365345 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0364783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0352223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0351615 |
| GPHN | gephyrin | -0.0350635 |
| SEPTIN7 | septin 7 | -0.0349292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348385 |
| MCL1 | myeloid cell leukemia 1 | -0.0343823 |
| GNAS | GNAS complex locus | -0.0342998 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0337026 |
| RPL9 | ribosomal protein L9 | -0.033372 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.032096 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0320466 |
| RPS12 | ribosomal protein S12 | -0.0319955 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0319848 |
| RPS24 | ribosomal protein S24 | -0.0317925 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0316066 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0313124 |
| RPS15 | ribosomal protein S15 | -0.031075 |
| RPL5 | ribosomal protein L5 | -0.0310357 |
| TUBA1B | tubulin, alpha 1b | -0.030744 |
| RECQL | RecQ helicase-like | -0.0305109 |
| CLTC | clathrin, heavy chain (Hc) | -0.0304861 |
| RPL32 | ribosomal protein L32 | -0.030167 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0300289 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0296955 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295612 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0289161 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0284283 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0281734 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0278977 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.0275768 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0274331 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0268173 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.026688 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0264437 |
| STK4 | serine/threonine kinase 4 | -0.0261829 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0261784 |
| TWF1 | twinfilin actin binding protein 1 | -0.0261607 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0259514 |
| RPS19 | ribosomal protein S19 | -0.0256913 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0254668 |
| RPL6 | ribosomal protein L6 | -0.0254379 |
| CCDC91 | coiled-coil domain containing 91 | -0.0253634 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0251918 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0250742 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0249285 |
| RPL23 | ribosomal protein L23 | -0.0248987 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0248171 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0246563 |
| GOLT1B | golgi transport 1B | -0.0244756 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0243475 |
| PCDH7 | protocadherin 7 | -0.0242048 |
| PKM | pyruvate kinase, muscle | -0.0241088 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0240661 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0240082 |
| RPS27 | ribosomal protein S27 | -0.0239748 |
| JAK1 | Janus kinase 1 | -0.0239007 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.0237836 |
| IL6ST | interleukin 6 signal transducer | -0.0237339 |
| RPS6 | ribosomal protein S6 | -0.0237042 |
| BSG | basigin (Ok blood group) | -0.0235711 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0235508 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0234798 |
