| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0516549 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0439532 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0429779 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.036573 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0253011 |
| MCL1 | myeloid cell leukemia 1 | 0.0220023 |
| VMP1 | vacuole membrane protein 1 | 0.0210676 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0194954 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0192379 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0192002 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0186823 |
| COPA | coatomer protein complex, subunit alpha | 0.0183316 |
| STC1 | stanniocalcin 1 | 0.0178533 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0177616 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0174702 |
| RNF145 | ring finger protein 145 | 0.01734 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0171009 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0157958 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0148615 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.014786 |
| GOLGA4 | golgin A4 | 0.0147588 |
| MSN | moesin | 0.0146362 |
| VEGFA | vascular endothelial growth factor A | 0.013952 |
| FLNB | filamin B, beta | 0.0139148 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0134669 |
| FMNL2 | formin-like 2 | 0.0134647 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0133518 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0132725 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0131546 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.012719 |
| RPS18 | ribosomal protein S18 | 0.0126464 |
| NGLY1 | N-glycanase 1 | 0.0125403 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0125363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0122748 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0119555 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0119237 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.011722 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0115232 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0114463 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0112395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0112341 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0111543 |
| CTBP2 | C-terminal binding protein 2 | 0.011148 |
| FAM219A | family with sequence similarity 219, member A | 0.0110531 |
| NUP58 | nucleoporin 58 | 0.0109108 |
| FAM13B | family with sequence similarity 13, member B | 0.0108891 |
| AUTS2 | autism susceptibility candidate 2 | 0.0108285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0106773 |
| MT2A | metallothionein 2A | 0.0105464 |
| RPL3 | ribosomal protein L3 | 0.0104107 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0104044 |
| PGM3 | phosphoglucomutase 3 | 0.0103889 |
| RPL21 | ribosomal protein L21 | 0.0102751 |
| PTEN | phosphatase and tensin homolog | 0.0101961 |
| DNER | delta/notch-like EGF repeat containing | 0.0101497 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0100986 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00985309 |
| NBEAL1 | neurobeachin-like 1 | 0.00969343 |
| TMEM165 | transmembrane protein 165 | 0.00966964 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00963909 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.00949568 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.00946033 |
| MOSMO | modulator of smoothened | 0.00942145 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00934055 |
| HMGA2 | high mobility group AT-hook 2 | 0.00913827 |
| GLRX | glutaredoxin (thioltransferase) | 0.00893379 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00892965 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00890243 |
| MLKL | mixed lineage kinase domain-like | 0.00888007 |
| ATP13A3 | ATPase type 13A3 | 0.00885516 |
| BMP6 | bone morphogenetic protein 6 | 0.00885283 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00883353 |
| FNIP1 | folliculin interacting protein 1 | 0.00860098 |
| FAM120A | family with sequence similarity 120A | 0.00858898 |
| SRP54 | signal recognition particle 54kDa | 0.00858042 |
| YOD1 | YOD1 deubiquitinase | 0.00856517 |
| TNRC6C | trinucleotide repeat containing 6C | 0.00840371 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00833509 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00827205 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00816781 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00813268 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00812524 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00811744 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00787152 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00778753 |
| RCOR1 | REST corepressor 1 | 0.00774649 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00768183 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00766727 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.007659 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00758051 |
| DHFR | dihydrofolate reductase | 0.00756424 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.00754658 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.00752217 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.00750685 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00748569 |
| XYLT1 | xylosyltransferase I | 0.00744585 |
| UBAP1 | ubiquitin associated protein 1 | 0.00741753 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00737497 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00734418 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00730687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.31357 |
| ASPH | aspartate beta-hydroxylase | -0.137463 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132947 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.128097 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127723 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.127673 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.12299 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.116637 |
| EFNA5 | ephrin-A5 | -0.106482 |
| TXNRD1 | thioredoxin reductase 1 | -0.100459 |
| PDE10A | phosphodiesterase 10A | -0.0974969 |
| COL5A2 | collagen, type V, alpha 2 | -0.0971624 |
| FN1 | fibronectin 1 | -0.0915525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0848755 |
| SMYD3 | SET and MYND domain containing 3 | -0.0848167 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0837066 |
| NRCAM | neuronal cell adhesion molecule | -0.0752142 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0699724 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0696002 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0661527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0653706 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0605059 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0588028 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0538178 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0528517 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0512633 |
| TMSB10 | thymosin beta 10 | -0.0509886 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0503137 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0500968 |
| CDH13 | cadherin 13 | -0.049313 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0460355 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0425239 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0421031 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0418255 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0418082 |
| PGK1 | phosphoglycerate kinase 1 | -0.0417207 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0410369 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0402472 |
| GRAMD1B | GRAM domain containing 1B | -0.0392216 |
| TNPO1 | transportin 1 | -0.0392041 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0389574 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.03842 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0382574 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0379002 |
| GDA | guanine deaminase | -0.0369382 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0357231 |
| PTGR1 | prostaglandin reductase 1 | -0.035686 |
| RPS24 | ribosomal protein S24 | -0.03513 |
| PALLD | palladin, cytoskeletal associated protein | -0.0347286 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0338581 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0333446 |
| GNAS | GNAS complex locus | -0.0323116 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0323057 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0316969 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0315253 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0313496 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0313424 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0311968 |
| LDHA | lactate dehydrogenase A | -0.0300772 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0299003 |
| MYOF | myoferlin | -0.0294812 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0289472 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0287001 |
| ANXA1 | annexin A1 | -0.0286279 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0275341 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0274736 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0273831 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0271216 |
| DOCK4 | dedicator of cytokinesis 4 | -0.026972 |
| RBM39 | RNA binding motif protein 39 | -0.0267757 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0264203 |
| TBXT | T-box transcription factor T | -0.0262312 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0259957 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0257869 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0257258 |
| ENO1 | enolase 1, (alpha) | -0.0257198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0255769 |
| RGS2 | regulator of G-protein signaling 2 | -0.0254251 |
| CDK6 | cyclin-dependent kinase 6 | -0.0247682 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0243844 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239931 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0239029 |
| CADM2 | cell adhesion molecule 2 | -0.0235286 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.023479 |
| LSAMP | limbic system-associated membrane protein | -0.0234092 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0228635 |
| CENPF | centromere protein F, 350/400kDa | -0.0227185 |
| SRGN | serglycin | -0.0225377 |
| EZR | ezrin | -0.0222447 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0221407 |
| PRKD3 | protein kinase D3 | -0.0219458 |
| INHBA | inhibin, beta A | -0.0219456 |
| RPS4X | ribosomal protein S4, X-linked | -0.0217438 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0217419 |
| ANXA2 | annexin A2 | -0.0216324 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0214001 |
| RPLP0 | ribosomal protein, large, P0 | -0.0213323 |
| TUSC3 | tumor suppressor candidate 3 | -0.0212933 |
| MAP1B | microtubule-associated protein 1B | -0.0210374 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0209825 |
