| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LRRC49 | leucine rich repeat containing 49 | 0.184335 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.126233 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.113649 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.102624 |
| FN1 | fibronectin 1 | 0.101869 |
| MYOF | myoferlin | 0.0886271 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0881479 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0869047 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.085891 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0799113 |
| DST | dystonin | 0.0787779 |
| SBF2 | SET binding factor 2 | 0.0781466 |
| GPC6 | glypican 6 | 0.0696544 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0693068 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0677564 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0674251 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0673703 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0659112 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0649338 |
| CLTC | clathrin, heavy chain (Hc) | 0.0645532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0639409 |
| COG6 | component of oligomeric golgi complex 6 | 0.0628499 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0626317 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0625921 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0610223 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0607645 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0602877 |
| PRELID2 | PRELI domain containing 2 | 0.0600169 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0593657 |
| DENND4C | DENN/MADD domain containing 4C | 0.0589832 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0584296 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0584114 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0582169 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0575755 |
| RBM39 | RNA binding motif protein 39 | 0.0575629 |
| SETD5 | SET domain containing 5 | 0.0564376 |
| SNX25 | sorting nexin 25 | 0.0560572 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0555205 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0545343 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0521782 |
| MKI67 | marker of proliferation Ki-67 | 0.0510688 |
| EGFR | epidermal growth factor receptor | 0.0504056 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0503381 |
| USP34 | ubiquitin specific peptidase 34 | 0.0499595 |
| USP15 | ubiquitin specific peptidase 15 | 0.0486805 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0481325 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0472717 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0466919 |
| GPHN | gephyrin | 0.0465256 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0455035 |
| HDLBP | high density lipoprotein binding protein | 0.0451506 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0445674 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0444121 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0435107 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0426529 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0424679 |
| RIGI | RNA sensor RIG-I | 0.0422953 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0417628 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0415422 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0414538 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0408867 |
| ATXN1 | ataxin 1 | 0.0408779 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.040874 |
| FMNL2 | formin-like 2 | 0.040861 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0404583 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0397117 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0372687 |
| COG5 | component of oligomeric golgi complex 5 | 0.0370757 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.036339 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0359655 |
| KIF5B | kinesin family member 5B | 0.0356972 |
| ZNF638 | zinc finger protein 638 | 0.0355599 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0354464 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0352019 |
| USP3 | ubiquitin specific peptidase 3 | 0.0347514 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0339399 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0332361 |
| YAP1 | Yes-associated protein 1 | 0.032688 |
| B2M | beta-2-microglobulin | 0.0318419 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0318092 |
| FAM13A | family with sequence similarity 13, member A | 0.0317998 |
| UBC | ubiquitin C | 0.0314377 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0307314 |
| FNIP1 | folliculin interacting protein 1 | 0.0307183 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0295946 |
| SRPK2 | SRSF protein kinase 2 | 0.0290189 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0280982 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0278906 |
| MED13 | mediator complex subunit 13 | 0.0278674 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0276874 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0274573 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.026029 |
| OGA | O-GlcNAcase | 0.0260129 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0259862 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251324 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0251206 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.025051 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0248445 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0248097 |
| RNF145 | ring finger protein 145 | 0.0244679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20867 |
| VIM | vimentin | -0.143621 |
| ASPH | aspartate beta-hydroxylase | -0.141227 |
| RPLP2 | ribosomal protein, large, P2 | -0.108681 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0971336 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0963699 |
| TMSB10 | thymosin beta 10 | -0.0883079 |
| RPS16 | ribosomal protein S16 | -0.0846799 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0790686 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0778918 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0767699 |
| ITGA6 | integrin, alpha 6 | -0.0765808 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0741591 |
| SNX9 | sorting nexin 9 | -0.0701056 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0670584 |
| MT2A | metallothionein 2A | -0.0649408 |
| RPLP1 | ribosomal protein, large, P1 | -0.0645652 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0641532 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0636844 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0631582 |
| RPS8 | ribosomal protein S8 | -0.0629294 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0626001 |
| RPS27A | ribosomal protein S27a | -0.0614627 |
| LAMA4 | laminin, alpha 4 | -0.0614507 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0601305 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0586343 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0559168 |
| RPL19 | ribosomal protein L19 | -0.0551158 |
| RPL23 | ribosomal protein L23 | -0.0549644 |
| PARD3 | par-3 family cell polarity regulator | -0.0520957 |
| ACTG1 | actin gamma 1 | -0.0515543 |
| LAMB3 | laminin, beta 3 | -0.0503974 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0502848 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0494733 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0486507 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.047662 |
| RPL12 | ribosomal protein L12 | -0.0476096 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0473155 |
| LDHA | lactate dehydrogenase A | -0.0458448 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0433888 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0432419 |
| JMJD1C | jumonji domain containing 1C | -0.0421053 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0419861 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0417947 |
| FTL | ferritin, light polypeptide | -0.041232 |
| MED13L | mediator complex subunit 13-like | -0.0410767 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0403767 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0400499 |
| GNAS | GNAS complex locus | -0.0397458 |
| RPS19 | ribosomal protein S19 | -0.0395131 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0393195 |
| RACK1 | receptor for activated C kinase 1 | -0.039127 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0390584 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0381817 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0381571 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0371542 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0368281 |
| JUN | jun proto-oncogene | -0.036626 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0364421 |
| RPLP0 | ribosomal protein, large, P0 | -0.0363683 |
| EGR1 | early growth response 1 | -0.0363229 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0361148 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0357802 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0353516 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0352882 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0349011 |
| PRKCA | protein kinase C, alpha | -0.0347674 |
| RPL37 | ribosomal protein L37 | -0.0343114 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0340217 |
| EZR | ezrin | -0.0339167 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0333935 |
| RPS24 | ribosomal protein S24 | -0.033333 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0328147 |
| SP100 | SP100 nuclear antigen | -0.0321008 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0320816 |
| BBX | bobby sox homolog (Drosophila) | -0.0319368 |
| ZNF207 | zinc finger protein 207 | -0.0316216 |
| MAP4 | microtubule-associated protein 4 | -0.0308704 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0307882 |
| RPL26 | ribosomal protein L26 | -0.0304702 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0304692 |
| RPL27A | ribosomal protein L27a | -0.0303225 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0294814 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0294564 |
| IGF2 | insulin-like growth factor 2 | -0.0291039 |
| SPATA13 | spermatogenesis associated 13 | -0.0290474 |
| TNPO1 | transportin 1 | -0.0279741 |
| RPL11 | ribosomal protein L11 | -0.027939 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0278639 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0275687 |
| RPL35A | ribosomal protein L35a | -0.0274583 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0273566 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0272364 |
| PTMA | prothymosin, alpha | -0.0267194 |
| MCL1 | myeloid cell leukemia 1 | -0.0266457 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0260148 |
| WASF2 | WAS protein family, member 2 | -0.0258734 |
| BPTF | bromodomain PHD finger transcription factor | -0.0257338 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0254125 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0249891 |
