| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.103714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.068416 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.062193 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0568815 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0555766 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0554137 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.052304 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0463421 |
| RPL3 | ribosomal protein L3 | 0.0459187 |
| RASA2 | RAS p21 protein activator 2 | 0.0433356 |
| NAV3 | neuron navigator 3 | 0.041455 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0370515 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0370181 |
| WDR43 | WD repeat domain 43 | 0.0370003 |
| NUP58 | nucleoporin 58 | 0.0354193 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0342831 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0342182 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0340603 |
| SRPK2 | SRSF protein kinase 2 | 0.0333924 |
| SET | SET nuclear proto-oncogene | 0.0330653 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0321755 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0319939 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0318737 |
| RPS18 | ribosomal protein S18 | 0.0317799 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0314974 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0308601 |
| RTN4 | reticulon 4 | 0.0303221 |
| MCL1 | myeloid cell leukemia 1 | 0.0287795 |
| ATP13A3 | ATPase type 13A3 | 0.0281176 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.027818 |
| ANXA5 | annexin A5 | 0.0275686 |
| VMP1 | vacuole membrane protein 1 | 0.0274977 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0272104 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0263733 |
| FOXJ3 | forkhead box J3 | 0.0262902 |
| RPS2 | ribosomal protein S2 | 0.0262511 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.026161 |
| SPAG9 | sperm associated antigen 9 | 0.026051 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0259883 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0254449 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0252305 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0250185 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0247356 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0245575 |
| RNF145 | ring finger protein 145 | 0.0244827 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0242971 |
| PNN | pinin, desmosome associated protein | 0.0241066 |
| DGKI | diacylglycerol kinase, iota | 0.0238758 |
| SNX9 | sorting nexin 9 | 0.0238642 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0232496 |
| RBM33 | RNA binding motif protein 33 | 0.0230781 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230312 |
| TPM3 | tropomyosin 3 | 0.0228694 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0228484 |
| GOLGA4 | golgin A4 | 0.0228067 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.022348 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0221468 |
| TPR | translocated promoter region, nuclear basket protein | 0.0220074 |
| RBM5 | RNA binding motif protein 5 | 0.0216783 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0211143 |
| USP34 | ubiquitin specific peptidase 34 | 0.0211127 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0210856 |
| BBX | bobby sox homolog (Drosophila) | 0.0210457 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0209321 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0206069 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0205198 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0201252 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0200316 |
| PHF3 | PHD finger protein 3 | 0.0196192 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0194669 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0190727 |
| DIAPH1 | diaphanous-related formin 1 | 0.0190593 |
| COPA | coatomer protein complex, subunit alpha | 0.0190343 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0190224 |
| WDR26 | WD repeat domain 26 | 0.0189062 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0188945 |
| NCKAP1 | NCK-associated protein 1 | 0.0187263 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0186937 |
| TRAM1 | translocation associated membrane protein 1 | 0.0186935 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0186136 |
| SBF2 | SET binding factor 2 | 0.0185432 |
| CAPRIN2 | caprin family member 2 | 0.0184631 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0184108 |
| PCBP2 | poly(rC) binding protein 2 | 0.0184003 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.018396 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0183648 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0183042 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0179006 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0178854 |
| STC1 | stanniocalcin 1 | 0.017852 |
| SLMAP | sarcolemma associated protein | 0.01783 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0178071 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0174417 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0174142 |
| HDGF | hepatoma-derived growth factor | 0.0173408 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0173259 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0173183 |
| CORO1C | coronin, actin binding protein, 1C | 0.017272 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0171855 |
| RCOR1 | REST corepressor 1 | 0.0170197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.143268 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.140426 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123353 |
| ACTG1 | actin gamma 1 | -0.10064 |
| HMGA2 | high mobility group AT-hook 2 | -0.090156 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.089717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0843996 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0843553 |
| FRMD6 | FERM domain containing 6 | -0.080153 |
| RPL12 | ribosomal protein L12 | -0.0746927 |
| TMSB10 | thymosin beta 10 | -0.0743516 |
| RPLP1 | ribosomal protein, large, P1 | -0.0689645 |
| TTR | transthyretin | -0.063145 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0607379 |
| RPL8 | ribosomal protein L8 | -0.057402 |
| RPS8 | ribosomal protein S8 | -0.0546329 |
| ZNF438 | zinc finger protein 438 | -0.0541839 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0510342 |
| RPL30 | ribosomal protein L30 | -0.0510059 |
| AHNAK | AHNAK nucleoprotein | -0.0491146 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.048835 |
| SP100 | SP100 nuclear antigen | -0.0487939 |
| NABP1 | nucleic acid binding protein 1 | -0.0485335 |
| PGK1 | phosphoglycerate kinase 1 | -0.0484112 |
| RPL32 | ribosomal protein L32 | -0.0473845 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.047093 |
| RPL35A | ribosomal protein L35a | -0.0454938 |
| RPL23 | ribosomal protein L23 | -0.0454686 |
| RPS19 | ribosomal protein S19 | -0.045408 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0451825 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0447903 |
| RPLP0 | ribosomal protein, large, P0 | -0.0408562 |
| MTDH | metadherin | -0.0403931 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0384389 |
| RPL19 | ribosomal protein L19 | -0.0380423 |
| JUN | jun proto-oncogene | -0.0379188 |
| RPS29 | ribosomal protein S29 | -0.0379134 |
| MTAP | methylthioadenosine phosphorylase | -0.0375928 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0370859 |
| RPS25 | ribosomal protein S25 | -0.0370317 |
| SPIDR | scaffolding protein involved in DNA repair | -0.036268 |
| RPL36 | ribosomal protein L36 | -0.035839 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0347818 |
| RPL9 | ribosomal protein L9 | -0.0345384 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0340774 |
| TCF12 | transcription factor 12 | -0.0338704 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0338263 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0333135 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0329025 |
| RPL31 | ribosomal protein L31 | -0.0326585 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0325909 |
| RPS21 | ribosomal protein S21 | -0.0320714 |
| RPS4X | ribosomal protein S4, X-linked | -0.0313048 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0313006 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0308584 |
| RPS24 | ribosomal protein S24 | -0.0306471 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0298742 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0295056 |
| RPL34 | ribosomal protein L34 | -0.0288986 |
| ENO1 | enolase 1, (alpha) | -0.0287674 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0287523 |
| CALU | calumenin | -0.0286613 |
| RPS5 | ribosomal protein S5 | -0.0285722 |
| S100A2 | S100 calcium binding protein A2 | -0.0284388 |
| ERBIN | erbb2 interacting protein | -0.0280966 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0280385 |
| TPM4 | tropomyosin 4 | -0.027859 |
| GNAS | GNAS complex locus | -0.0278524 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0272398 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0270857 |
| HLA-C | major histocompatibility complex, class I, C | -0.0269023 |
| FUS | FUS RNA binding protein | -0.0265408 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0260026 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.025812 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0257876 |
| RPS20 | ribosomal protein S20 | -0.0257482 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0255183 |
| NFIA | nuclear factor I/A | -0.0254968 |
| RPL13A | ribosomal protein L13a | -0.0250918 |
| DEK | DEK proto-oncogene | -0.0246288 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244769 |
| AHI1 | Abelson helper integration site 1 | -0.0243698 |
| RPS27A | ribosomal protein S27a | -0.0242817 |
| PKP4 | plakophilin 4 | -0.0241938 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0241934 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.02407 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0239886 |
| GPHN | gephyrin | -0.0239694 |
| RPL18 | ribosomal protein L18 | -0.0239631 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0238858 |
| FTL | ferritin, light polypeptide | -0.0237032 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0236997 |
| LDHA | lactate dehydrogenase A | -0.0235548 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0235014 |
| MT1X | metallothionein 1X | -0.0234807 |
| SQLE | squalene epoxidase | -0.02338 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0233234 |
| RIGI | RNA sensor RIG-I | -0.0231843 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0230505 |
| RPL28 | ribosomal protein L28 | -0.022844 |
