| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.17676 |
| VEGFA | vascular endothelial growth factor A | 0.150129 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.125704 |
| B2M | beta-2-microglobulin | 0.113682 |
| MSN | moesin | 0.0815682 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0752599 |
| STC1 | stanniocalcin 1 | 0.075021 |
| POTEF | POTE ankyrin domain family, member F | 0.0595122 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553788 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0550748 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0541146 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0530381 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0502953 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0490409 |
| ATP13A3 | ATPase type 13A3 | 0.0480351 |
| DOCK5 | dedicator of cytokinesis 5 | 0.045235 |
| CALR | calreticulin | 0.0434765 |
| PGK1 | phosphoglycerate kinase 1 | 0.0423919 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0416413 |
| COPA | coatomer protein complex, subunit alpha | 0.0410388 |
| PTK2 | protein tyrosine kinase 2 | 0.040451 |
| RNF145 | ring finger protein 145 | 0.0403651 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.040157 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0400461 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0399973 |
| THBS1 | thrombospondin 1 | 0.0390972 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0378568 |
| ZNF148 | zinc finger protein 148 | 0.0378363 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0371039 |
| SETD5 | SET domain containing 5 | 0.037044 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0362677 |
| ZNF292 | zinc finger protein 292 | 0.0361628 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0352711 |
| MKI67 | marker of proliferation Ki-67 | 0.0350009 |
| ECT2 | epithelial cell transforming 2 | 0.0349762 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0345514 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0345151 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0344756 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0338279 |
| WDR43 | WD repeat domain 43 | 0.0335862 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0329171 |
| NBAS | neuroblastoma amplified sequence | 0.0326313 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0325951 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0324924 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0324566 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0324484 |
| CD44 | CD44 molecule (Indian blood group) | 0.0323454 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0315165 |
| CENPF | centromere protein F, 350/400kDa | 0.0314148 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0313185 |
| INSIG2 | insulin induced gene 2 | 0.0312257 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0308416 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0307502 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0305216 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0304228 |
| CDK19 | cyclin-dependent kinase 19 | 0.0297997 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0296113 |
| NCKAP1 | NCK-associated protein 1 | 0.0295097 |
| NUP58 | nucleoporin 58 | 0.0291444 |
| GOLGA4 | golgin A4 | 0.0290679 |
| FOXJ3 | forkhead box J3 | 0.0290117 |
| ZNF207 | zinc finger protein 207 | 0.0285061 |
| TGM2 | transglutaminase 2 | 0.0284783 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284558 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0283159 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.028202 |
| RHOA | ras homolog family member A | 0.0280202 |
| PCM1 | pericentriolar material 1 | 0.0278774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0278694 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0277379 |
| KIF5B | kinesin family member 5B | 0.0275992 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0275921 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.027357 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0272632 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0270315 |
| CORO1C | coronin, actin binding protein, 1C | 0.0270217 |
| SBF2 | SET binding factor 2 | 0.0266812 |
| MATR3 | matrin 3 | 0.0266083 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0266071 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0263825 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260773 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0260359 |
| YEATS2 | YEATS domain containing 2 | 0.025973 |
| TMF1 | TATA element modulatory factor 1 | 0.0257589 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.025604 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.02528 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0247566 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0247294 |
| FLNB | filamin B, beta | 0.0245091 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0244113 |
| TPM3 | tropomyosin 3 | 0.0243939 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.024322 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0240277 |
| CRLS1 | cardiolipin synthase 1 | 0.0240159 |
| XPO1 | exportin 1 | 0.0238953 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0238527 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0237462 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0237239 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0234658 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0231568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.160067 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13726 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.104697 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0923283 |
| FTL | ferritin, light polypeptide | -0.0837073 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0829877 |
| NDRG1 | N-myc downstream regulated 1 | -0.0662724 |
| CDH13 | cadherin 13 | -0.0630047 |
| FHIT | fragile histidine triad | -0.0602374 |
| COL1A1 | collagen, type I, alpha 1 | -0.0573246 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0571008 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.052259 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0522231 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0519065 |
| EGR1 | early growth response 1 | -0.0512156 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0507642 |
| SP100 | SP100 nuclear antigen | -0.0506695 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0494793 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0454592 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450185 |
| TMSB10 | thymosin beta 10 | -0.0449477 |
| TMEM178B | transmembrane protein 178B | -0.0446488 |
| FBXO32 | F-box protein 32 | -0.0441852 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0428765 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0418185 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0411459 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.040029 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0394643 |
| GNAS | GNAS complex locus | -0.0375493 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0363869 |
| COL1A2 | collagen, type I, alpha 2 | -0.0352286 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349473 |
| PTMA | prothymosin, alpha | -0.0344658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0338439 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.033041 |
| CADM1 | cell adhesion molecule 1 | -0.0329247 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0328124 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0327491 |
| SQSTM1 | sequestosome 1 | -0.0327332 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0325764 |
| JUN | jun proto-oncogene | -0.0322059 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0321593 |
| NREP | neuronal regeneration related protein | -0.0319761 |
| XAF1 | XIAP associated factor 1 | -0.0316318 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0310725 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0308595 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0308308 |
| RPS8 | ribosomal protein S8 | -0.0305478 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0297773 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0295927 |
| NAV1 | neuron navigator 1 | -0.0295048 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0291171 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0290156 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0287516 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0285374 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0283245 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0280976 |
| IER3 | immediate early response 3 | -0.0280196 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0279612 |
| ANXA2 | annexin A2 | -0.0276052 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0275865 |
| NABP1 | nucleic acid binding protein 1 | -0.027303 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0271897 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0270309 |
| INTS6 | integrator complex subunit 6 | -0.0267534 |
| RND3 | Rho family GTPase 3 | -0.0265811 |
| RPL23 | ribosomal protein L23 | -0.0263153 |
| TNNC1 | troponin C type 1 (slow) | -0.0260938 |
| RIGI | RNA sensor RIG-I | -0.0257598 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255859 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0253699 |
| RRBP1 | ribosome binding protein 1 | -0.0252891 |
| TMEM263 | transmembrane protein 263 | -0.0246465 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0245745 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0243771 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0242499 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0238924 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.02378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0237347 |
| RPS24 | ribosomal protein S24 | -0.0235926 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0234476 |
| SDCBP | syndecan binding protein (syntenin) | -0.0234343 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0233811 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0232017 |
| HM13 | histocompatibility (minor) 13 | -0.0226227 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0224469 |
| GLIS3 | GLIS family zinc finger 3 | -0.0223302 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0222595 |
| CAVIN1 | caveolae associated protein 1 | -0.0222492 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0221995 |
| HLA-C | major histocompatibility complex, class I, C | -0.0221204 |
| RPL35A | ribosomal protein L35a | -0.021944 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0218876 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0215937 |
| TJP1 | tight junction protein 1 | -0.0213905 |
| RPL32 | ribosomal protein L32 | -0.0212149 |
| FRMD4A | FERM domain containing 4A | -0.0211925 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0211381 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0209681 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0209136 |
