| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0804998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0637904 |
| VEGFA | vascular endothelial growth factor A | 0.0592051 |
| GOLGA4 | golgin A4 | 0.0514282 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0510553 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0501695 |
| RPS6 | ribosomal protein S6 | 0.0496806 |
| RAD51B | RAD51 paralog B | 0.0492428 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0460733 |
| SETD5 | SET domain containing 5 | 0.0445532 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0439879 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0399086 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0384571 |
| CALD1 | caldesmon 1 | 0.0374578 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0373141 |
| NOTCH2 | notch 2 | 0.0358637 |
| RPS3 | ribosomal protein S3 | 0.0344026 |
| MATR3 | matrin 3 | 0.0342531 |
| PRELID2 | PRELI domain containing 2 | 0.0341093 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.033542 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333345 |
| TPM3 | tropomyosin 3 | 0.0333306 |
| CEP250 | centrosomal protein 250kDa | 0.0331986 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0327626 |
| MSI2 | musashi RNA-binding protein 2 | 0.0320083 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0316126 |
| TOB2 | transducer of ERBB2, 2 | 0.0313988 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.031374 |
| MT2A | metallothionein 2A | 0.0308748 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0306596 |
| MSN | moesin | 0.0304017 |
| NGLY1 | N-glycanase 1 | 0.0292432 |
| TRIM33 | tripartite motif containing 33 | 0.0287451 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.028264 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0280124 |
| B2M | beta-2-microglobulin | 0.0268065 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0267948 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0263283 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0262216 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0262094 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0256243 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0256225 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0254566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0254126 |
| CDH13 | cadherin 13 | 0.0249165 |
| CTTN | cortactin | 0.0244448 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0242206 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.023608 |
| DIAPH1 | diaphanous-related formin 1 | 0.0234693 |
| TRIM44 | tripartite motif containing 44 | 0.023418 |
| SET | SET nuclear proto-oncogene | 0.0232131 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0227989 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.022739 |
| WWOX | WW domain containing oxidoreductase | 0.0227093 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0226301 |
| RBM25 | RNA binding motif protein 25 | 0.0226017 |
| RNF145 | ring finger protein 145 | 0.0220118 |
| CABIN1 | calcineurin binding protein 1 | 0.022003 |
| ZC3H7B | zinc finger CCCH-type containing 7B | 0.0211113 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0210578 |
| TENM3 | teneurin transmembrane protein 3 | 0.0209843 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0208969 |
| TNS1 | tensin 1 | 0.0205191 |
| EFNA5 | ephrin-A5 | 0.0202288 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0201449 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0198781 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.019686 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.019342 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0190417 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0190318 |
| RPL35A | ribosomal protein L35a | 0.0188025 |
| NKTR | natural killer cell triggering receptor | 0.0187293 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0185324 |
| VMP1 | vacuole membrane protein 1 | 0.0185077 |
| HDAC4 | histone deacetylase 4 | 0.0184812 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0184203 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.018382 |
| RPS17 | ribosomal protein S17 | 0.0180798 |
| DSTN | destrin (actin depolymerizing factor) | 0.0180436 |
| CDK19 | cyclin-dependent kinase 19 | 0.0179709 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0178822 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0178582 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0178031 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0177526 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.017676 |
| FAM219A | family with sequence similarity 219, member A | 0.0175244 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0174341 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0172826 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0172193 |
| POTEF | POTE ankyrin domain family, member F | 0.0170099 |
| FAM13A | family with sequence similarity 13, member A | 0.016945 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0168991 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0167772 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0166972 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0166396 |
| HPCAL1 | hippocalcin-like 1 | 0.0166065 |
| YEATS2 | YEATS domain containing 2 | 0.0165635 |
| RHOA | ras homolog family member A | 0.0165618 |
| COPA | coatomer protein complex, subunit alpha | 0.0165065 |
| AUTS2 | autism susceptibility candidate 2 | 0.0165051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0999567 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.093654 |
| FMN1 | formin 1 | -0.0799931 |
| NRG3 | neuregulin 3 | -0.0784252 |
| PGK1 | phosphoglycerate kinase 1 | -0.0755725 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0683635 |
| RUNX1 | runt-related transcription factor 1 | -0.0642725 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0637955 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0546748 |
| CCND1 | cyclin D1 | -0.0541041 |
| FRMD5 | FERM domain containing 5 | -0.0536978 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0513064 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0483804 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0467307 |
| MAP4 | microtubule-associated protein 4 | -0.0449501 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0437311 |
| NDRG1 | N-myc downstream regulated 1 | -0.0432628 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0423897 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0411012 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.040911 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0393325 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.038576 |
| TNNC1 | troponin C type 1 (slow) | -0.0377399 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0370269 |
| SQSTM1 | sequestosome 1 | -0.0365568 |
| SPAG9 | sperm associated antigen 9 | -0.0363856 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0361576 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.035467 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0348993 |
| TXNRD1 | thioredoxin reductase 1 | -0.034871 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0341899 |
| TMSB10 | thymosin beta 10 | -0.0341521 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0330979 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0328913 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0322823 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0308783 |
| RASAL2 | RAS protein activator like 2 | -0.0308668 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.030729 |
| LDHA | lactate dehydrogenase A | -0.0302801 |
| TFRC | transferrin receptor | -0.0295493 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.029019 |
| TKT | transketolase | -0.028631 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0282303 |
| HDAC9 | histone deacetylase 9 | -0.0280755 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0279381 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.027414 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0263881 |
| RYBP | RING1 and YY1 binding protein | -0.0262964 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0262843 |
| RPL38 | ribosomal protein L38 | -0.0260823 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0259654 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0257839 |
| RPL4 | ribosomal protein L4 | -0.0257323 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0255997 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0255677 |
| FILIP1 | filamin A interacting protein 1 | -0.0255091 |
| RPS24 | ribosomal protein S24 | -0.0249132 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0246974 |
| TULP4 | tubby like protein 4 | -0.0246234 |
| AHNAK | AHNAK nucleoprotein | -0.0245704 |
| NAV2 | neuron navigator 2 | -0.0245366 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.024177 |
| DIAPH2 | diaphanous-related formin 2 | -0.0233729 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0229999 |
| ACTG1 | actin gamma 1 | -0.0226925 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0226679 |
| CLTC | clathrin, heavy chain (Hc) | -0.0224391 |
| COG5 | component of oligomeric golgi complex 5 | -0.0223275 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0222795 |
| RHEB | Ras homolog enriched in brain | -0.0220263 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0219349 |
| RPL34 | ribosomal protein L34 | -0.0219013 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0218655 |
| CDK6 | cyclin-dependent kinase 6 | -0.0215774 |
| ACTN4 | actinin, alpha 4 | -0.0213219 |
| TNPO1 | transportin 1 | -0.0212955 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0211877 |
| EMP1 | epithelial membrane protein 1 | -0.0210733 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0210497 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0209783 |
| ZNF207 | zinc finger protein 207 | -0.0209312 |
| PLCB4 | phospholipase C, beta 4 | -0.0208986 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0208047 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0206375 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.020489 |
| OXSR1 | oxidative stress responsive 1 | -0.0204538 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0203289 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.020259 |
| FOXO3 | forkhead box O3 | -0.0200931 |
| PCNX1 | pecanex 1 | -0.0200817 |
| FRMD6 | FERM domain containing 6 | -0.0196221 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0194618 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0193822 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0193523 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0193098 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0191437 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0189555 |
| RPS4X | ribosomal protein S4, X-linked | -0.018949 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0187739 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0187654 |
